Mortality throughout the world due to cutaneous melanoma has been increasing over the past two decades, accounting for 3% of deaths caused by cancer. Because survival rates increase substantially when diagnosed at an early stage, successful treatment of melanoma depends on early detection. We have been working to develop optical spectroscopy for the noninvasive detection of skin cancer. We have investigated the use of Raman, diffuse reflectance and fluorescence spectroscopy for the noninvasive detection of skin cancer.
Zhang Y, Moy AJ, Feng X, Nguyen HTM, Reichenberg JS, Markey MK, Tunnell JW. Physiological model using diffuse reflectance spectroscopy for non‐melanoma skin cancer diagnosis. J Biophotonics (e201900154), 2019
Lim L, Nichols B, Migden M, Rajaram N, , Reichenberg J, Tunnell JW. Noninvasive diagnosis of melanoma and nonmelanoma using muilti-modal spectroscopy. J Biomed Opt 19(11):117003, 2014
Sharma M, Marple E, Reichenberg J, Tunnell JW. Design and characterization of a novel multimodal fiber-optic probe and spectroscopy system for skin cancer applications. Rev Sci Instr 85, 083101, 2014
Hennessey R, Lim L, Markey M, Tunnell JW. Monte Carlo lookup table-based inverse model for extracting optical properties from tissue simulating phantoms using diffuse reflectance spectroscopy. J Biomed Opt 18(3): 037003, 2013