The research programs of CMCT Faculty have the unifying theme: to define host responses to environmental toxicants and to dissect the influence of genetic background, developmental age and diet on these responses.
It should be noted that some training faculty may fit into more than one of the 4 defined areas which facilitates collaborative interactions and interdisciplinary research and training.
C. Marcelo Aldaz, M.D., Professor, UT MD Anderson Cancer Center, Science Park-Research Division; Breast cancer, hormonal carcinogenesis; Mammary tumor models.
David Crews, Ph.D., Professor of Integrative Biology; The influence of biological and chemical factors during early vertebrate development that lead to alterations in behavior and sexual function.
Richard H. Finnell, Ph.D., Professor, Department of Nutritional Sciences and Director of Genomic Research at the Dell Children’s Medical Center; Study of the interaction between specific genes and nutritional factors as they influence normal embryonic development; revealing the relationships between the folic acid metabolic pathway and risk genes associated with birth defects.
Laura K. Fonken, Ph.D., Assistant Professor of Pharmacology and Toxicology; Study of interactions between the endocrine, nervous, and immune systems. Current projects focus on endogenous (e.g. circadian rhythms) and exogenous (e.g. infection and injury) factors that influence neuroimmune function across the lifespan.
Andrea C. Gore, Ph.D., Professor of Pharmacology and Toxicology; Neural mechanisms of reproductive development and puberty, Effects of environmental and hormonal factors that perturb reproductive function, Neural mechanisms for reproductive senescence.
John H. Richburg, Ph.D., Professor of Pharmacology and Toxicology; Mechanisms Regulating Apoptosis/Male Reproductive Toxicology. Peripubertal sensitivity to testicular toxicants.
Peter Thomas, Ph.D., Professor of Zoology and Marine Science; Reproductive endocrine toxicology, mechanisms of endocrine disruption by xenobiotic chemicals, environmental toxicology of aquatic organisms.
Carla Van Den Berg, PharmD., Associate Professor of Pharmacology and Toxicology; Role of growth factor-mediated treatment resistance in breast cancer.
Ying Xu, Ph.D., Assistant Professor of Civil, Architectural, & Environmental Engineering; Fate and transport of semi-volatile endocrine disrupting compounds (e.g. phthalates, PBDEs, and organophosphates), human exposure to endocrine disrupting compounds, environmental modeling, indoor environment quality and healthy building.