Publications

JOURNAL ARTICLES

  1. Fonken, L.K., Frank, M.G., D’Angelo, H.M., Heinze, J.D., Watkins, L.R., Lowry, C.A., & Maier, S.F. (2018). Mycobacterium vaccae immunization protects aged rats from surgery-elicited neuroinflammation and cognitive dysfunction. Neurobiology of Aging: In press.
  2. Frank, M.G., Fonken, L.K., Watkins, L.R., Maier, S.F., & Lowry, C.A. (2018). Could probiotics be used to mitigate neuroinflammation? ACS Chemical Neuroscience: In press.
  3. Fonken, L.K., Frank, M.G., Gaudet, A.D., & Maier, S.F. (2018). Stress and aging act through common mechanisms to elicit neuroinflammatory priming. Brain, Behavior, and Immunity: In press.
  4. Frank, M.G., Fonken, L.K., Dolzani, S.D., Annis, J.L., Siebler, P.H., Heinze, J.D., Schmidt, D., Watkins, L.R., Maier, S.F., & Lowry, C.A. (2018). M. vaccae treatment induces an anti-inflammatory milieu in the CNS: attenuation of stress-induced microglial priming, alarmins, and anxiety-like behavior. Brain, Behavior, and Immunity: In press.
  5. Gaudet, A.D. & Fonken, L.K. (2018). Glial cells shape pathology and repair after spinal cord injury. Neurotherapeutics: In press.
  6. Sun, Q., Zhang, G., Chen, R., Wang, H., Jiang, A., Li, Z., Li, R., Kong, K., Fonken, L.K., Rajagopalan, S., Sun, Q., & Lui, C. (2018). Central IKK2 inhibition ameliorates air pollution mediated hepatic glucose and lipid metabolism dysfunction in mice with type II diabetes. Toxicological Sciences: 164 (1): 240-249.
  7. Fonken, L.K., Frank, M.G., Gaudet, A.D., D’Angelo, H.M., Daut, R.D. Hampson, E.C., Ayala, M.T., Watkins, L.R., & Maier, S.F. (2018). Neuroinflammatory priming to stress is differentially regulated in male and female rats. Brain, Behavior, and Immunity 70: 257-267.
  8. Frank, M.G., Fonken, L.K., Annis, J., Watkins, L.R., & Maier, S.F. (2018). Stress disinhibits microglia via down-regulation of CD200: a mechanism of neuroinflammatory priming. Brain, Behavior, and Immunity 69: 62-73.
  9. Gaudet, A.D., Fonken, L.K., Watkins, L.R., Nelson, R.J., & Popovich, P.G. (2018). microRNAs: Roles in regulating neuroinflammation. The Neuroscientist 24 (3): 221-245.
  10. Fonken, L.K., Kitt, M.M., Gaudet, A.D., Barrientos, R.M., Watkins, L.R., & Maier, S.M. (2016). Diminished circadian rhythms in microglia may contribute to age-associated neuroinflammatory priming. Neurobiology of Aging 47: 102-112.
  11. Fonken, L.K., Frank, M.G., Kitt, M.M., D’Angelo, H.M., Norden, D.M., Weber, M.D., Barrientos, R.M., Godbout J.P., Watkins, L.R., & Maier, S.F. (2016). The alarmin HMGB1 mediates age-induced neuroinflammatory priming. The Journal of Neuroscience 36 (30): 7946-7956.
  12. Gaudet, A.D.*, Fonken, L.K.*, Gushchina, L.V., Aubrecht, T.G., Maurya, S.K., Periasamy, M., Nelson, R.J., & Popovich, P.G. (2016). MicroRNA-155 deletion prevents diet-induced obesity in female mice. Scientific Reports 6: 22862. *equal contributors
  13. Fonken, L.K., Weber, M.D., Daut, R.A., Kitt, M.M., Frank, M.G., Watkins, L.R., & Maier, S.F. (2016). Stress induced neuroinflammatory priming is time of day specific. Psychoneuroendocrinology 66: 82-90.
  14. Fonken, L.K.*, Gaudet, A.D.*, Gaier, K.R.*, Nelson, R.J., & Popovich, P.G. (2016). MicroRNA-155 deletion reduces anxiety- and depressive-like behaviors in mice. Psychoneuroendocrinology 63: 362-369. *equal contributors
  15. Frank, M.G., Weber, M.D., Fonken, L.K., Hershman, S.A., Watkins, L.R., & Maier, S.F. (2016). The redox state of the alarmin HMGB1 is a pivotal factor in neuroinflammatory and microglial priming: a role for the NLRP3 inflammasome. Brain, Behavior, and Immunity 55: 215-224.
  16. Bedrosian, T.A., Fonken, L.K., & Nelson, R.J. (2016). Endocrine effects of circadian disruption. Annual Review of Physiology 78 (1).
  17. Fonken, L.K. & Nelson, R.J. (2016). Effects of light exposure at night during development. Current Opinion in Behavioral Sciences 7: 33-39.
  18. Fonken, L.K., Frank, M.G., Kitt, M.M., Barrientos, R.M., Watkins, L.R., & Maier, S.F. (2015). Microglia inflammatory responses are controlled by an intrinsic circadian clock. Brain, Behavior, and Immunity 45: 171-179.
  19. Fonken, L.K. & Nelson, R.J. (2014). The effects of light at night on circadian clocks and metabolism. Endocrine Reviews 35 (4): 648-670.
  20. Fonken, L.K., Meléndez-Fernández, O.H., Weil, Z.M., & Nelson, R.J. (2014). Exercise attenuates the effects of dim light at night on metabolism. Physiology and Behavior 124: 33-36.
  21. Lui C.*, Fonken, L.K.*, Wang, A., Maiseyeu, A., Bai, Y., Wang, T., Maurya, S., Ko, Y., Periasamy, M., Dvonch, T., Morishita, M., Brook, R.D., Harkema, J., Ying, Z., Mukherjee, B., Sun, Q., Nelson, R.J., & Rajagopalan, S. (2014) Central IKK inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Particle and Fibre Toxicology 11(1): 53. *equal contributors
  22. Fonken, L.K., Aubrecht, T.G., Melendez-Fernandez, O.H., Weil, Z.M., & Nelson, R.J. (2013). Dim light at night disrupts molecular circadian rhythms and increases body weight. Journal of Biological Rhythms 28(4): 262-71
  23. Fonken, L.K. & Nelson, R.J. (2013). Dim light at night increases depressive-like responses in male C3H/HeNHsd mice. Behavioural Brain Research. 243: 74-78.
  24. Fonken, L.K., Weil, Z.M., & Nelson, R.J. (2013). Dark nights reverse metabolic disruption caused by dim light at night. Obesity 21 (6): 1159-64.
  25. Bedrosian, T.A., Herring, K.L., Walton, J.C., Fonken, L.K., Weil, Z.M., & Nelson, R.J. (2013). Evidence for feedback control of pineal melatonin secretion. Neuroscience Letters 542: 123-5.
  26. Fonken, L.K., Lieberman, R.A., Weil, Z.M., & Nelson, R.J. (2013). Dim light at night exaggerates weight gain and inflammation associated with a high fat diet in male mice. Endocrinology 154 (10): 3817-25.
  27. Fonken, L.K. & Nelson, R.J. (2013). Mice exposed to dim light at night exaggerate inflammatory responses to lipopolysaccharide. Brain, Behavior, and Immunity 34: 159-63.
  28. Fonken, L.K., Haim, A., & Nelson, R.J. (2012). Dim light at night increases immune function in grass rats, a diurnal rodent. Chronobiology International. 29 (1): 26-34.
  29. Bedrosian, T.A., Fonken, L.K., Demas, G.E., & Nelson, R.J. (2012). Photoperiod-dependent effects of neuronal nitric oxide synthase inhibition on aggression in Phodopus sungorus. Hormones and Behavior. 61 (2): 176-80.
  30. Fonken, L.K., Bedrosian, T.A., Michaels, H., Weil, Z.M., & Nelson, R.J. (2012). Short photoperiods attenuate central responses to an inflammogen. Brain, Behavior, and Immunity. 26 (4): 617-22.
  31. Fonken, L.K., Kitsmiller, E., Smale, L., & Nelson, R.J. (2012). Dim nighttime light impairs cognition and provokes depressive-like responses in a diurnal rodent. Journal of Biological Rhythms. 27 (4): 319-27.
  32. Fonken, L.K., Xu, X., Weil, Z.M., Chen, G., Sun, Q., Rajagopalan, S., & Nelson, R.J. (2011). Air pollution impairs cognition, provokes depressive-like behaviors, and alters hippocampal cytokine expression and morphology. Molecular Psychiatry. 16 (10): 987-995.
  33. Fonken, L.K., Xu, X., Weil, Z.M., Chen, G., Sun, Q., Rajagopalan, S., & Nelson, R.J. (2011). Inhalation of fine particulates alters hippocampal neuronal morphology. Molecular Psychiatry. 16 (10): 973.
  34. Fonken, L.K., Morris, J.S., & Nelson, R.J. (2011). Early life experiences affect adult delayed-type hypersensitivity in short- and long-photoperiods. Chronobiology International, 28 (2): 101-108.
  35. Bedrosian, T.A., Fonken, L.K., Walton, J.C., & Nelson, R.J. (2011). Chronic exposure to dim light at night suppresses immune responses in Siberian hamsters. Biology Letters, 7 (3): 468-471.
  36. Bedrosian, T.A., Fonken, L.K., Walton, J.C., Haim, A., & Nelson, R.J. (2011). Dim light at night provokes depression-like behaviors and reduces CA1 dendritic spine density in female hamsters. Psychoneuroendocrinology, 36 (7): 1062-9.
  37. Fenn, A.M.*, Fonken, L.K.*, & Nelson, R.J. (2011). Sustained melatonin treatment blocks body mass, pelage, reproductive and fever responses to short day lengths in female Siberian hamsters. Journal of Pineal Research, 51 (2): 180-186. *equal contributors
  38. Workman, J.L., Fonken, L.K., Gusfa, J., Kassouf, K., & Nelson, R.J. (2011). Post-weaning environmental enrichment reduces negative affective responses and interacts with behavioral testing to alter nNOS expression. Pharmacology, Biochemistry and Behavior, 100 (1): 25-32.
  39. Fonken, L.K. & Nelson, R.J. (2011). Illuminating the deleterious effects of light at night. F1000 Med Report, 3: 18.
  40. Fonken, L.K., Workman, J.L., Walton, J.C., Weil, Z.M., Morris, J.S., Haim, A., & Nelson, R.J. (2010). Light at night increases body mass by shifting the time of food intake. Proceedings of the National Academy of Sciences, 107 (43): 18664-18669. * featured in F1000 and popular press
  41. Workman, J.L., DeWitt, S.J., Fonken, L.K., & Nelson, R.J. (2010). Environmental enrichment enhances delayed-type hypersensitivity in both short- and long-day Siberian hamsters. Physiology and Behavior, 99 (5): 638-643.
  42. Thomas, N.R., Fonken, L.K., LeBlanc, M., & Cornwell, C.A. (2010). Maternal separation alters social odor preference development in infant mice (Mus musculus). Journal of Comparative Psychology, 124 (3): 295-301.
  43. Fonken, L.K., Finy, M.S., Walton, J.C., Weil, Z.M., Workman, J.L., Ross, J., & Nelson, R.J. (2009). Influence of light at night on murine anxiety- and depressive-like responses. Behavioural Brain Research. 205 (2): 349-354.