Work in Dr. Ghosh’s lab focuses on biologically-inspired, rational design of biomolecules (i.e. peptides and proteins) and nanoscale materials for therapeutics in cancer and mucosal-associated diseases. One area of emphasis is the use of combinatorial libraries to identify peptides that achieve transport through biological barriers, including the blood-brain barrier, mucus, and in solid tumors. From this information, design criteria can be developed towards the design of drug carriers that achieve improved, therapeutic delivery. Another long-term goal of the lab is to exploit the biology of diseases to develop biological nanoparticles that achieve successful delivery of therapeutic agents.
For more information, visit the Ghosh Lab Site.