39. Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion. Ouzon-Shbeita H, Vilas CK, Lee S. Biochem J. 2020, in press.

38. Bypass of the major alkylative DNA lesion by human DNA polymerase η. Koag MC, Jung H, Kou Y, Lee S. Molecules 2019, 24, 3928 

37. Promutagenicity of 8-chloroguanine, a major inflammation-induced halogenated DNA lesion. Kou Y, Koag MC, Lee S. Molecules 2019, 24, 3507

36. Photo-induced DNA interstrand cross-links formed by a coumarin-modified nucleoside. Rozelle AL, Kumar RN, Lee S. Nucleosides Nucleotides Nucleic Acids. 2019;38(3):236-247.

35. Mutagenic replication of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine by human DNA polymerases. Koag MC, Jung H, Lee S. J Am Chem Soc. 2019, 141(11):4584-4596.

34. Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase η. Ouzon-Shubeita H, Baker M, Koag MC, Lee S. Biochem J. 2019 476(4):747-758. doi: 10.1042/BCJ20180848.

33. Structural and kinetic studies of the effect of guanine N7 alkylation and metal cofactors on DNA replication. Kou Y, Koag MC, Lee S. Biochemistry. 2018, 57, 5105-5116.

32. Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β. Koag, MC; Lee, S. Biochem J. 2018 Feb 9;475(3):571-585. (recommende for F1000Prime).31. Synthesis and bioactivity of bis-steroidal pyrazine 23-deoxy-25-epi ritterostatin GN1N. Kumar, RN.; Lee, S.* Steroids 2017, 126, 74-78.

 30. Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate. Cheun Y, Koag MC, Naguib YW, Ouzon-Shubeita H, Cui Z, Pakotiprapha D, Lee S. Chem Biol Drug Des. 2017  doi: 10.1111/cbdd.13062.

29. Synthesis of 23-deoxy-25-epi north unit of cephalostatin 1 via reductive and oxidative modifications of hecogenin acetate. Kumar, N.; Lee, S.*  Steroids 2017, 118, 68-75

28. cis-Diammine[3-(3-chloro-7-methoxy-9,10-dihydroacridin-9-ylideneamino)propan-1-aminej2 N,N0]platinum(II) dinitrate. Cheun, Y.; Lee, S*. IUCrData (2016). 1, x160481.


27. N7 methylation alters hydrogen-bonding patterns of guanine in duplex DNA. Kou, Y.; Koag, M.; Lee, S.* J. Am. Chem. Soc. 2015, 137, 14067.

26. Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesions by human DNA polymerase β. Koag, M.; Lai, L.; Lee, S.* J. Biol. Chem. 2014, 289, 31341.    

25. The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase β. Koag, M.; Nam, K.*; Lee, S.* Nucleic Acids Res. 2014, 42, 11233.      

24. Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine. Koag, M.; Kou, Y.; Ouzon, H.; Lee, S.Nucleic Acids Res. 2014, 42, 8755-8766.      


23. Streamlining bottom-up protein identification based on selective UVPD of chromophore-tagged histidine- and tyrosine-containing peptides. Aponte, J.; Vasicek, L.; Waminathan, J.; Xu, H.; Koag, M.; Lee, S.; Brodbelt, J. S.*Anal. Chem. 2014, 86, 6237-6244.     

22. Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase β.Koag, M.; Lee, S.* J. Am. Chem. Soc. 2014, 136, 5709-5721. (Recommended for F1000Prime)  

21. Structural basis for the promutagenicity of 8-bromoguanine. Koag, M.; Min, K.§; Lee, S. *J. Biol. Chem. 2014, 289, 6289-6298.


20. Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4. Koag, M.; Cheun, Y.; Kou, Y.; Ouzon-Shubeita, H.; Min, K.§; Monzingo, A. F.; Lee, S.* Steroids, 2013, 79, 938-944.

19. Unexpected opening of steroidal E-ring during hypoiodite-mediated oxidation. Kou, Y.; Lee, S.*. Tetrahedron Lett. 2013, 54, 4106-4109. 


18. Synthesis of C17-OH-north unit of ritterazine G via “Red-Ox” modifications of hecogenin acetate. Cheun, Y.; Kou, Y.; Stevenson, B.; Kim, H.; Koag, M.; Lee, S.* Steroids, 2013, 78, 639-643.

17. Synthesis of 14′,15′-dehydro-ritterazine Y via reductive and oxidative functionalizations of hecogenin acetate. Kou, Y.; Cheun, Y.; Koag, M.; Lee, S.* Steroids, 2013, 78, 304-311.   

16. Application of hypoiodite-mediated aminyl radical cyclization to synthesis of solasodine acetate. Kou, Y.; Cheun, Y.; Koag, M.; Shin, A§.; Lee, S.* Steroids, 2012, 77, 1069-1074.   

15. Transetherification-mediated E-ring opening and stereoselective “Red-Ox” modification of furostan.Cheun, Y.; Koag, M.; Kou, Y.; Warnken, Z.;  Lee, S.* Steroids 2012, 77, 276-281.   

14. Discovery of hypoiodite-mediated aminyl radical cyclization lacking a nitrogen radical-stabilizing group: Application to synthesis of an oxazaspiroketal-containing cephalostatin analog.Koag, M.; Lee, S.* Org. Lett., 2011, 13, 4766–4769.  

13. Structure of Escherichia coli 3-methyladenine DNA glycosylase AlkA bound to  undamaged DNA. Bowman, B. R.; Lee, S.; Wang, S.; Verdine, G. L.*  J. Biol. Chem. 2010, 285, 35783-791.   

12. Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Lee, S.; Verdine, G. L.* Proc. Natl. Acad. Sci. USA 2009, 106, 18497.  

11. Chemistry of trisdecacyclic pyrazine antineoplastics: The cephalostatins and ritterazines. Lee, S.; LaCour, T. G.; Fuchs, P. L.* Chem. Rev. 2009, 109, 2275.       

10. Synthesis of C14,15-dihydro-25-epi north unit of cephalostatin 1 via redox modifications of hecogenin acetate. Lee, S.*; Jamieson, D.; Fuchs, P. L.* Org. Lett. 2009, 11, 5.

9. Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. Lee, S.; Bowman, R. B.; Ueno, Y.; Verdine, G. L.* J. Am. Chem. Soc. 2008, 130, 11570.   8. Trapping and structural elucidation of a very advanced intermediate in the lesion-extrusion pathway of hOGG1 (highlighted in Nat. Chem. Biol. 2008, 4, 395)                   Lee, S.; Radom, C. T. Verdine, G. L.* J. Am. Chem. Soc. 2008, 130, 7784. 

 7. Structure of the Escherichia coli DNA glycosylase AlkA bound to the ends of duplex DNA: A system for the facile structure determination of lesion-containing DNA.Bowman, B. R§.; Lee, S. §; Verdine, G. L.* Structure 2008, 16, 1166.   

6. A Concise synthesis of 4′-F nucleic acids. Lee, S.; Utammapinat, C.; Verdine, G. L.* Org. Lett. 2007, 9, 5007.                                                         

5. In situ nitrosonium ion generation. Oximinylation of enol ethers from steroidal spiroketals. Introduction of C23-OH in cephalostatin intermediates. Lee, S.; Fuchs, P. L.* Can. J. Chem. 2006, 84, 1442.


4. An efficient C-H oxidation protocol for the α-hydroxylation of cyclic steroidal ethers. Highly efficient, regio- and stereoselective oxyfunctionalization of steroids by Cr[VI]. Lee, S.; Fuchs, P. L.* Org. Lett. 2004, 6, 1437.   

3. Chemospecific chromium[VI] catalyzed oxidation of C-H bonds at -40 oC. Lee, S.; Fuchs, P. L.* J. Am. Chem. Soc. 2002, 124, 13978.

2. The first total synthesis of ritterazine M. Lee, S.; Fuchs, P. L.* Org. Lett. 2002, 4, 317..                               

1. Redox functionalization of steroid spiroketals. Structure correction of ritterazine M. Lee, S.; LaCour, T. G.; Lantrip, D. A.; Fuchs, P. L.* Org. Lett. 2002, 4, 313. 



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