My projects focus on the role of uncoupling proteins and mitochondrial metabolism in the regulation of muscle physiology and pathology.
Heat shock proteins (HSPs) are involved in the cellular response to noxious stimuli such as toxicity, oxidative stress, hyperthermia and inflammation. A recently characterized mitochondrial HSP named cvHSP is expressed most highly in the heart, skeletal muscle, and adipose tissues. My project focuses on exploring the physiological role of HSP with specific emphasis on protein-protein interactions with mitochondrial proteins and its effects on mitochondrial metabolism.
B.S. Biology, Rice University, Houston, TX
Institute for Cell and Molecular Biology