Representative Publications

Recent and Representative Publications

  1. Jope, R.S., Morrisett, R.A., Snead, O.C. Characterization of lithium potentiation of pilocarpine-induced status epilepticus in rats. Experimental Neurology. 91:471-480, 1986.
  2. Morrisett, R.A., Chow, C., Nadler, J.V., McNamara, J.O. Biochemical evidence for enhanced sensitivity to N-methyl-D-aspartate in the hippocampal formation of kindled rats. Brain Research 496:25-28, 1989.
  3. Morrisett, R.A., Martin, D., Savage, D., Wilson, W.A., Swartzwelder, H.S. Prenatal ethanol exposure decreases sensitivity of adult rat hippocampus to N-methyl-Daspartate. Alcohol 6:415-420, 1989.
  4. Morrisett, R.A., Rezvani, A.H., Overstreet, D., Janowsky, D.S., Wilson, W.A., Swartzwelder, H.S. MK-801 potently inhibits alcohol withdrawal seizures in rats. European J Pharmacology 176:103-105, 1990.
  5. Morrisett, R.A., Mott, D.O., Lewis, D.V., Swartzwelder, H.S., Wilson, W.A. GABABmediated inhibition of the NMDA component of synaptic transmission in area CA1 of rat hippocampus. J Neuroscience 11:203-209, 1991.
  6. Morrisett, R.A., Martin, D., Oetting, T.A., Wilson, W.A., Swartzwelder, H.S. Ethanol and Mg++ inhibit N-methyl-D-aspartate mediated synaptic potentials in an interactive manner. Neuropharmacology 30:1173-1178, 1991.
  7. Hosford, D., Clark, S., Cao Z., Wilson, W.A., Lin, F-H., Morrisett, R.A., Huin, A. Activation of GABAB receptors in lethargic mice with absence seizures. Science 257:398-401, 1992.
  8. Morrisett, R.A., Swartzwelder, H.S. Attenuation of hippocampal long-term potentiation by ethanol: A patch clamp analysis of glutamatergic and GABAergic mechanisms. J Neuroscience 13:2264-2272, 1993.
  9. Buller, A.L., Clark, H.C., Schneider, B.J., Morrisett, R.A., Monaghan, D.T. Anatomical and pharmacological properties of NMDA receptor subtypes: Native pharmacology predicted by subunit composition. J Neuroscience 14:5471-5484, 1994.
  10. Thomas, M.P., Webster, W.W., Norgren, R.B., Monaghan, D.T., Morrisett, R.A. Survival and functional demonstration of interregional pathways in fore/midbrain slice explant cultures, Neuroscience 85:615-626, 1998.
  11. Thomas, M.P., Davis, M.I., Monaghan, D.T., Morrisett, R.A. Organotypic brain slice cultures for functional analysis of alcohol-related disorders: Novel versus conventional preparations. Alcoholism: Clinical Experimental Research 22:51-59, 1998.
  12. Thomas, M.P., Monaghan, D.T., Morrisett, R.A. Evidence for a causative role of NMDA receptors in an in vitro model of alcohol withdrawal hyperexcitability. J Pharmacology Experimental Therapeutics 287:87-97, 1998.
  13. Lewohl, J.M., Wilson, W.R., Mayfield, R.D., Brozowski, S.J., Morrisett, R.A. and Harris, R.A. G-protein-coupled inwardly rectifying potassium channels: Targets of ethanol action. Nature Neuroscience 2:1084-1090, 1999.
  14. Thomas, M.P. and Morrisett, R.A. Dynamics of NMDAR-mediated neurotoxicity during chronic ethanol exposure and withdrawal. Neuropharmacology 39:218-226, 2000.
  15. Hendricson, A.W., Miao, C.L.A., Lippmann, M.J., Morrisett, R.A. Ifenprodil and ethanol enhance NMDA receptor-dependent long-term depression. J Pharmacology Experimental Therapeutics 301:938-944, 2002. PMID: 12023522
  16. Maldve, R.E., Zhang, T.A., Ferrani-Kile, K., Schreiber, S.S., Lippmann, M.J., Snyder, G.L., Fienberg, A.A., Leslie, S.W., Gonzales, R.A., Morrisett, R.A. DARPP-32 and regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens. Nature Neuroscience 5:641-648, 2002.
  17. Hendricson, A.W., Thomas, M.P., Lippmann, M.P., Morrisett, R.A. Suppression of Ltype voltage-gated calcium channel dependent synaptic plasticity by ethanol: Analysis of miniature synaptic currents and dendritic calcium transients. J Pharmacology Experimental Therapeutics 307:550-558, 2003. PMID: 12970285
  18. Hendricson, A.H., Sibbald J.R., Morrisett, R.A. Ethanol alters the frequency, amplitude, and decay kinetics of Sr2+ -supported, asynchronous NMDAR mEPSCs in rat hippocampal slices. J Neurophysiology 91:2568-2577, 2004. PMID: 14749312
  19. Zhang T.A., Hendricson, A.W., Morrisett, R.A. Dual synaptic sites of D1-dopaminergic regulation of ethanol sensitivity of NMDA receptors in nucleus accumbens. Synapse 58:30-44, 2005.
  20. Hendricson, A.W., Maldve, R.E., Salinas, A.G., Theile, J.W., Zhang, T.A., Diaz, L.M., Morrisett, R.A. Aberrant synaptic activation of NMDA receptors underlies ethanol withdrawal hyperexcitability, J Pharmacology Experimental Therapeutics, 321:60-72, 2007.
  21. Theile, J.W., Morikawa, H., Gonzales, R.A., Morrisett, R.A. Ethanol enhances GABAergic transmission onto dopamine neurons in the ventral tegmental area of the rat. Alcoholism:Clinical Experimental Research, 32:1040-48, 2008.
  22. Theile, J.W., Morikawa H., Gonzales R.A.., Morrisett, R.A. Role of 5-HT2c receptors in Ca2+ -dependent ethanol potentiation of GABA release onto ventral tegmental area dopamine neurons. J Pharmacology Experimental Therapeutics., 329:625-33, 2009.
  23. Jeanes Z.M., Buske T.R., Morrisett R.A. In vivo chronic intermittent ethanol exposure reverses the polarity of synaptic plasticity in the Nucleus Accumbens shell. J Pharmacology Experimental Therapeutics., 336:155-64, 2011.
  24. Theile J.W., Morikawa, H., Gonzales, R.A. Morrisett, R.A. GABAergic transmission modulates ethanol excitation of ventral tegmental area dopamine neurons. Neuroscience, 172:94-103, 2011.
  25. Salinas, A.G., Nguyen, C.T., Ahmadi-Tehrani, D., Morrisett, R.A. Reduced ethanol consumption and preference in cocaine- and amphetamine-regulated transcript (CART) knockout mice. Addiction Biology, 19: 175-84, 2014.
  26. Jeanes ZM, Buske TR, Morrisett RA. Cell type-specific synaptic encoding of ethanol exposure in the nucleus accumbens shell. Neuroscience, epub ahead of print.
  27. Renteria, R, Jeanes ZM, Morrisett RA. , Ethanol attenuation of long term depression in the nucleus accumbens can be overcome by activation of TRPV1 receptors. Alcoholism: Clinical and Experimental Therapeutics, revision submitted.

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