From Discovery to Recovery: Defining therapeutic targets for brain and spinal cord injuries
From Discovery to Recovery
Defining Therapeutic Targets for Brain and Spinal Cord Injuries
Left Panel: Immunolocalization of PCP4 (a marker of Purkinje cells in the cerebellum) at 1 day after traumatic injury at postnatal day 21. Courtesy of Kaila Parker.
Middle Panel: Localization of blood vessels (green) in the injured spinal cord at 3 weeks after spinal cord injury. F480+macrophages (white arrows) are localized at the lesioned site (Trivedi et al, Experimental Neurology, 2016).
Right panel:In vivo 2-photon imaging of the developing brain after a mild closed head injury. Blood vessels (green), vascular tracer indicative of leakage (red), meningeal vessels (yellow, indicative of co-labeling with the vascular tracer). Courtesy of Michael Donovan.