The Proteomics Facility provides services, self-service equipment, and collaborative research for the detection, characterization, and quantification of proteins and other biomolecules. The facility labs are located in MBB 1.420 (College of Natural Sciences) and PHR 5.220 (College of Pharmacy). We are participating in the UT System Proteomics Core Facility Network.
Contact us by phone at 512-471-2895 or email to firstname.lastname@example.org
We are located at 2500 Speedway in MBB 1.420 and operating hours are M-F 9 am – 5 pm.
We have an online sample submission form if you would like to submit a sample to the Proteomics Facility. Please email the Proteomics Facility staff before submission for a consultation on what type of analysis is best for your experiment.
Please visit the Proteomics Facility Wiki for protocols and FAQs.
News and Announcements:
- Check out our Intavis DigestPro robot for robotic digest and desalting. Save time, pipettor’s thumb and get high reproducibility by taking advantage of automation.
- Specialized proteomics services are available via the UT System Proteomics Network. These include CyTOF, Reversed Phase Protein Arrays, top-down proteomics and UVPD fragmentation, glycoform analysis, and HDX exchange.
Core Services and Collaborative Projects:
- Protein/peptide molecular weight determination
- Protein identification by LC-MS/MS and database search for individual gel bands and complex mixtures including cell lysates
- Quantitative proteomics with spectral counting, peak area, or stable isotope labeling by TMT or iTRAQ
- Protein modification analysis for phosphorylation, methylation, acetylation, ubiquitinylation, glycosylation, inhibitor binding, and chemical adduct site determination
- Targeted proteomics for quantitation of selected proteins
- High resolution intact and top down protein analysis
- Top-down and UVPD analysis of intact proteins for cleavage characterization, ligand binding, and modification analysis through Jennifer Brodbelt‘s participation in UT System Proteomics Core Facility Network
Self-service instrumentation available:
When using core services, remember to cite the Proteomics Facility in your publications, and funding source CPRIT RP110782 when work was billed at subsidized CPRIT rate, and send the citation to Maria Person. Continued support for the facility depends on documented outcomes.
If you are interested in collaborating on a protein modification or quantitation project, contact Maria Person.
For top-down and UVPD, contact Jennifer Brodbelt.