Identification of “Lead candidate” is another critical step in drug discovery pipeline. For this challenging phase. TTP scientists work closely with investigator as well as core facilities on campus and GCC member institutes to achieve efficient Lead Characterization.
- Support target engagement using various in biophysical techniques (DSF, CD, SPR, BRET, NMR*, MS*)
- Support mechanism of action (MAO) studies
- Provide advice and/or service regarding the formulation* and evaluation of in vivo compound bioavailability* (pharmacokinetics studies) to facilitate in vivo efficacy studies
* Supports in integration with shared facilities.