Our plate readers are applicable for various application such as, but not limited to, Drug discovery, Enzyme kinetics, Cell proliferation, Cytotoxicity, Drug absorption and metabolism, Biologics drug discovery and development, Nucleic acid quantification, Protein quantification, Biomarker quantification, ELISAs, Genetics analysis.
Please refer plate reader chart for quick comparison and selection. TTP Plate reader comparison chart v1
Synergy Neo2 Plate reader(Biotek) Both filter-& monochromator based plate reader specific for assay development or low throughput screen, integrated plate stacker holding 20 plates and dispenser.
Synergy H4 Plate reader (Biotek) Both filter-& monochromator based plate reader specific for assay development or low throughput screen, integrated plate stacker holding 20 plates.
Cytation 5 cell imaging multi-mode reader(Biotek) Specific for dual cell imaging and multi-mode microplate reading on fluorescence, bright field, color bright field and phase contrast microscopy equipped with CO2/O2control and incubation (rt—60⁰C). Learn more about Cytation’s capability.
EnVision Plate Reader (Perkin Elmer) Specific for general assay development & high throughput screen equipped with an automated injection system for time-sensitive measurement and an integrated plate stacker holding 50 plates.
Flexstation-3-multi-mode-microplate-readers (Molecular Device)A benchtop system integrates multi-mode microplate optics with precision, programmable liquid handling for perfectly timed. Specific for fast kinetics assay development equipped with an temperature control up to 45⁰C).
Other Detection systems
IncuCyte® Live Cell Analysis System(Essen Bioscience) A compact dual fluorescent and HD-phase contrast imaging microscope housed in a standard incubator for real time quantitative live-cell imaging and analysis. Equipped with different microscope objectives (4x, 10x, 20x), read up to 6 microtiter plates, and acquired >2000 images per hour. Applications for cell health & viability (apoptosis, proliferation, cytotoxicity, tumor spheroids), live cell assays (angiogenesis, cell migration and invasion, immune cell clustering and proliferation), cell monitoring and workflow (cell culture QC, dilution cloning, reporter genes, stem cell monitoring and reprogramming, transfection efficiency)
J-815 CD spectrometer(Jasco) Specific for optically active chemicals and secondary structure analysis of biological molecules equipped with an auto-sampling (2 x 96 well plates), temp control (6—110⁰C) for thermal melting, wavelength range of 163-900 nm, & 6 cell simultaneous analysis. Specific applications are protein conformational studies, quantitative analysis of pharmaceuticals, formulation studies, protein folding studies, DNA/RNA interactions. Learn more about CD technology.
Comprehensive tools for data analysis can be found at http://dichroweb.cryst.bbk.ac.uk/html/home.shtml.
Cary 4000 UV-Vis(Agilent) High performance UV-Vis spectrometer, specific for Tm analysis of biological molecules equipped with an 6×6 pelitier cell holder, temp control (-10—100⁰C), wavelength range of 175-900 nm. Measure beyond 8.0 absorbance.
Biacore S200 (Cytiva) Most sensitive SPR instrument offering increased productivity in LMW/fragment drug discovery. 384 single-concentration fragment binding data can be acquired in less than 16 h. Equipped with 4 channels and capable of measurement of affinity, kinetics, concentration, and specificity of biological interactions between a ligand and an analyte in a real time format. Learn more about SPR technology.
QuantStudio 7 Pro RT-PCR (ThermoFisher) Real-time PCR system equipped with interchangeable 96-well, 384-well, and Taqman Array card blocks. Multiplexing up to 6 targets, 10 order of dynamic range, 1.5x resolution, compatible with diverse dyes, temperature ranges between 4-99.9°C, 21 filter or color combination, 6 independent temperature zones (96-well blocks). Specific for protein thermal shift (DSF), single-nucleotide polymorphism (SNP) genotyping, gene expression, high resolution melting, etc. Learn more about DSF technology.
Echo® 550 Liquid Handler (Bechman) Main screening liquid handler used for reagent or library transfer for assay, library reformatting, serial dilution, or cherry pick.
Janus Automated Workstation(Perkin Elmer) Main screening liquid handler used for reagent or library transfer for assay, library reformatting, serial dilution, or cherry pick.
Microflo Select (BioTek) Specific for rapid bulk liquid dispensing(1 uL ~1 mL) equipped with an integrated plate stacker up to 30 plates.
Multiflo Fx multi-mode Dispenser (BioTek) Specific for rapid bulk liquid dispensing(1 uL ~1 mL) equipped with an integrated plate stacker up to 30 plates and parallel dispensing technology.
EL405lx Plate washer (BioTek) Versatile application from basic ELISA to sensitive cell or bead washing with rapid wash of 96– or 384 microwell plates.
Computing cluster: 500-core Dell Linux cluster with Gigabit network and a 16 TB disk storage, 12 GTX1070 GPUs, Lonestar 5 (available from TACC, 30048 compute cores, 5 PB disk storage, 40 GPUs)
High-end Dell graphics workstation
Software: Datawarrior, Chemaxon, Daylight Reaction Toolkit, ROCS and EON (OpenEye), GOLD (CCDC), AMBER, GROAMCS, TINKER, OpenMM, Pymol, VMD, Chimera
Forma 3110 CO2 Incubator (37⁰C/5% CO2)
Leica DMi1 microscope (4x, 10x, 20x).
Biosafety hood, centrifuge, & water bath.
PlateLoc Plate Sealers.
Centrifuge 5810R (-4°C~40°C, ~14,000 rpm)
Bar Code Printer.
Trained and approved users can reserve instruments in advance and usage fees will be billed based on reservation records. Go to “Reservation“.
For the training or inquiries for instrument access, please contact Core Director, Eun Jeong Cho.