Instruments

Detection: Our plate readers are applicable for varius application such as, but not limited to, Drug discovery, Enzyme kinetics, Cell proliferation, Cytotoxicity, Drug absorption and metabolism, Biologics drug discovery and development, Nucleic acid quantification, Protein quantification, Biomarker quantification, ELISAs, Genetics analysis.

Synergy Neo2 Plate reader(Biotek) Both filter-& monochromator based plate reader specific for assay development or low throughput screen, integrated plate stacker holding 20 plates and dispenser.
Synergy H4 Plate reader (Biotek) Both filter-& monochromator based plate reader specific for assay development or low throughput screen, integrated plate stacker holding 20 plates.
Cytation  5 cell imaging multi-mode reader (Biotek) Specific for dual cell imaging and multi-mode microplate reading on fluorescence, brightfield, color brightfield and phase contrast microscopy equipped with CO2/O2control and incubation (rt—60⁰C). Learn more about Cytation’s capability.
EnVision Plate Reader (Perkin Elmer) Specific for general assay development & high throughput screen equipped with an automated injection system for time-sensitive measurement and an integrated plate stacker holding 50 plates.
FlexStation 3 Multi-Mode Microplate Reader (Molecular Device) A benchtop system integrates multi-mode microplate optics with precision, programmable liquid handling for perfectly timed. Specific for fast kinetics assay development equipped with an temperature control up to 45⁰C).
IncuCyte® Live Cell Analysis System(Essen Bioscience) A compact dual fluorescent and HD-phase contrast imaging microscope housed in a standard incubator for real time quantitative live-cell imaging and analysis. Equiped with different microscope objectives (4x, 10x, 20x), read up to 6 microtiter plates, and acquired >2000 images per hour. Applications for cell health & viability (apoptosis, proliferation, cytotoxicity, tumor spheroids), live cell assays (angiogenesis, cell migration and invasion, immune cell clustering and proliferation), cell monitoring and workflow (cell culture QC, dilution cloning, reporter genes, stem cell monitoring and reprogramming, transfection efficiency)
J-815 CD spectrometer(Jasco) Specific for optically active chemicals and secondary structure analysis of biological molecules equipped with an autosampling (2 x 96 well plates), temp control (6—110⁰C) for thermal melting, wavelength range of 163-900 nm, & 6 cell simultaneous analysis. Specific applications are protein conformational studies, quantitative analysis of pharmaceuticals, formulation studies, protein folding studies, DNA/RNA interactions
Cary 4000 UV-Vis(Agilent) High performance UV-Vis spectrometer, specific for Tm analysis of biological molecules equipped with an 6×6 pelitier cell holder, temp control (-10—100⁰C), wavelength range of 175-900  nm. Measure beyond 8.0 absorbance.

Liquid Handling

Echo® 550 Liquid Handler (LabCyte) Main screening liquid handler used for reagent or library transfer for assay, library reformatting, serial dilution, or cherry pick. 
Janus Automated Workstation(Perkin Elmer) Main screening liquid handler used for reagent or library transfer for assay, library reformatting, serial dilution, or cherry pick. 
Microflo Select (BioTek) Specific for rapid bulk liquid dispensing(1 uL ~1 mL) equipped with an integrated plate stacker up to 30 plates.

Microflo Fx multi-mode Dispenser (BioTek) Specific for rapid bulk liquid dispensing(1 uL ~1 mL) equipped with an integrated plate stacker up to 30 plates and parallel dispensing technology.
EL405lx Plate washer (BioTek) Versatile application from basic ELISA to sensitive cell or bead washing with rapid wash of 96– or 384 microwell plates.

Chemoinfomatics

Computing cluster: 500-core Dell Linux cluster with Gigabit network and a 16 TB disk storage, 12 GTX1070 GPUs, Lonestar 5 (available from TACC, 30048 compute cores, 5 PB disk storage, 40 GPUs)
High-end Dell graphics workstation
Software:Daylight Reaction Toolkit, ROCS and EON (OpenEye), GOLD (CCDC), GLIDE (Schrodinger), AMBER, GROAMCS, TINKER, OpenMM, Pymol, VMD, Chimera

Tissue culture

Forma 3110 CO2 Incubator (37⁰C/5% CO2).
Leica DMi1 microscope (4x, 10x, 20x).
Biosafety hood, centrifuge, & water bath.

Miscellaneous

ALPS 3000 & PlateLoc Plate Sealers.
VSpin micriocentrifuge &Centrifuge 5810R (-4°C~40°C, ~14,000 rpm)
Bar Code Printer.

Instrument Reservation

Trained and approved users can reserve instruments in advance and usage fees will be billed based on reservation records. Go to “Reservation“.
For the training or inquiries for instrument access, please contact Core Director, Eun Jeong Cho.

Download TTP Instrument