Welcome to Stephen Yi Laboratory !

About the PI – Prof. S. Stephen Yi

S. Stephen Yi is Director of Bioinformatics, Developmental Therapeutics Lab, at Livestrong Cancer Institutes and Dell Medical School of the University of Texas at Austin. He is also faculty at the Oden Institute for Computational Engineering and Sciences (ICES), the Institute for Cellular and Molecular Biology (ICMB), and the Department of Biomedical Engineering. Prof. Yi was conferred with numerous awards, including an NIH Outstanding Investigator Award, a Komen Scholar award, a Scialog Fellow award, an NIH Early Career Development Award, and Kenneth Shine Award for Excellence in Research Mentorship, for his work on signal transduction and network biology in human disease and translational therapeutics. He received his undergraduate’s degree from Peking University, and doctoral degree with distinction from University of Iowa. He completed a postdoctoral fellowship in Cancer Systems Biology at Harvard Medical School and Dana-Farber Cancer Institute.

Lab News

2023-Mar: Our deep learning paper on disease network medicine discovery was published at Comput Struct Biotechnol J. 
Our deep learning paper on neurological disease co-mutation vulnerability network was published at Briefings in Bioinformatics. Congratulations, Xingxin!
Our collaborative paper with Marc Mendillo’s lab (Northwestern) was published at Nature Communications
Our paper on microRNA network perturbations in cancer was published at Cancer Research
Our lab was just awarded with a NIH major instrument fund to support our spatial network multi-omics project!
We received a collaborative project grant with Scott Kopetz’s lab (MD Anderson), jointly funded by UT Austin and MD Anderson!
Our review paper on biomolecular condensation in cancer was published at Cancer Discovery. Thanks to the wonderful collaboration with Dan Jarosz (Stanford) and Nidhi Sahni (MD Anderson)!  
Prof. Yi won another Scialog Fellow Award in Advanced Bioimaging, by Chan Zuckerberg Initiative, RCSA and Cottrell Foundation. Thanks to our collaborator, Ruixuan Gao’s lab at University of Illinois at Chicago!  
Our deep learning paper on glioma multi-omics network-based drug discovery was published at Comput Struct Biotechnol J. Congratulations, Xingxin!
Prof. Yi won the first Scialog Fellow Award in Chemistry Machinery of the Cell, by Research Corporation for Science Advancement (RCSA) and Gordon & Betty Moore Foundation. Thanks to our collaborator, Jan-Hendrik Spille’s lab at University of Illinois at Chicago! 
We received a joint pilot grant with Ken Chen’s lab (MD Anderson), funded by Oden Institute, MD Anderson, and TACC Collaboration!
2021-Apr: Prof. Yi received the first inaugural Kenneth Shine Award for Excellence in Research Mentorship. Congratulations!
Our paper on isoform-mediated network gain of functions was accepted at Briefings in Bioinformatics
Prof. Yi was named an Associate Editor of the journal Oncogene, by Nature Publishing Group. Congratulations, Stephen!
2021-Jan: Our e-MutPath method on computational modeling of mutational effects was published at Nucleic Acids Research
Ishaani Khatri just won 2020 Prize for Undergraduate Research in Quantitative Biology by NSF-Simons Center. Congrats, Ishaani!
Rahul Pentaparthi was selected as a recipient of the Undergraduate Research Fellowship by the Vice President of Research at UT. Congrats, Rahul!
Robert Marick joined the lab as a rotation graduate student from the Interdisciplinary Life Sciences Graduate Programs (ILSGP). Welcome, Robert!
Our paper on integrated cancer immunome analysis was accepted at Cancer Research
Ishaani Khatri from Brown University joined the lab as a summer student in the Moncrief Scholarship program at Oden Institute. Welcome, Ishaani!
Sairahul (“Rahul”) Pentaparthi joined the lab as a honors program undergrad student. Welcome, Rahul!
Yue Liu joined the lab as a rotation graduate student from the ICMB program. Welcome, Yue!
2019-Sep: Prof. Yi received an NIH Outstanding Investigator Award (MIRA). Congratulations, Stephen!

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