Prof. Song (Stephen) Yi’s lab research is at the interface of human disease biology and informatics in the modern era of personalized precision medicine. His lab combines computational and experimental expertise to build a quantitative understanding of genetic/epigenetic variation and signaling network perturbation in disease. Currently, Prof. Yi’s research interests include tumor immunology and metabolism, synthetic lethality and drug resistance, next-gen sequencing analysis, signaling reprograming/engineering, and multi-omics network biology. He has a long-term interest in addressing fundamental questions in human disease underlying genotype-phenotype relationships. He is also dedicated in constantly developing new technologies to address these questions.