Degree: B.S., Wuhan University
Entered Group: Fall, 2015 (Chemistry program)
Research Projects: Mechanistic Studies of Unusual Enzymatic Cyclization Reactions
Group Publications:
Zhang, J.; Fan, P.-H.; Lin, G.-M.; Chang, W.-C.; Liu, H.-w. “Recent Progress in the Biosynthesis of Carbohydrate-Containing Natural Products.” In Comprehensive Chemistry of Natural Product Chemistry, Liu, H-w.; Begley, T., Eds.; Elsvier: New York;. 2020, 336-392.
Wang, S.-A.; Lin, C.-I.; Zhang, J.; Ushimaru, R.; Sasaki, E.; Liu, H.-w. “Studies of Lincosamide Formation Complete the Biosynthetic Pathway for Lincomycin A.” Proc. Natl. Acad. Sci. USA 2020, 117, 24794-24801.
Zhang, J.; Hou, X.; Chen, Z.; Ko, Y.; Ruszczycky, M. W.; Chen, Y.; Zhou, J,; Liu, H.-w. “Dioxane Bridge Formation in the Biosynthesis of Spectinomycin Involves a Twitch Radical SAM Dehydrogenase that Appears to Have Evolved from an Epimerase.” J. Am. Chem. Soc. 2022, 144, 9910-9919. [PMC9204835]
Chen, Z.; Sato. S.; Geng. Y., Zhang, J.; Liu, H.-w. “Identification of the Early Steps in Herbicidin Biosynthesis Reveals an Atypical C-Glycosylation.” J. Am. Chem. Soc. 2022, 144, in press.