Degree: B.S., Zhejiang University, China
Entered Group: Fall, 2018 (Chemistry program)
Research Projects: Mechanistic studies of the Biosynthesis of Secondary Metabolites
Group Publications:
Chen, T.-Y.; Zheng, Z.; Zhang, X.; Chen, J.; Cha, L.; Tang, Y.; Guo, Y.; Zhou, J.; Wang, B.; Liu, H.-w.; Chang, W.-c. “Decipher Reaction Pathway of Mononuclear Iron Enzymes Catalyzed N-C Triple Bond Formation in Isocyanide Lipopeptides and Polyketides Biosynthesis.” ACS Catalysis 2022, 12, 2270-2279.
Zheng, Z.; Xiong, J.; Bu, J.; Ren, D.; Lee, Y.-H.; Yeh, Y.-C.; Lin, C.-I.; Parry, R.; Guo, Y.; Liu, H.-w. “Reconstitution of the Final Steps in the Biosynthesis of Valanimycin Reveals the Origin of its Characteristic Azoxy Moiety.” Angew. Chem. Int. Ed. 2024, 63, e202315844. [PMC10843709]
Zheng, Z.; Lee, Y.-H.; Ruszczycky, M. W.; Ushimaru, R.; Liu, H.-w. “Twitch Radical S-Adenosyl L-Methionine Alcohol Dehydrogenases.” Encyclopedia Inorg. Bioinorg. Chem. 2024, eibc2869. [NIHMSID2015061]
Zheng, Z.; Clardy, J.; Liu, H.-w. “Biosynthesis of Unusual Epoxy Isonitrile-Containing Antibiotics Aerocyanidin and Amycomicin.” J. Am. Chem. Soc. 2024, 146, 21061-21068. [PMC11334264]
Zheng, Z.; Choi, H.; Liu, H.-w. “In Vitro Characterizsation of the Kitasetaline Biosynthesis Reveals a Novel P450 Decarboxylase and a Vinyl β-Carboline Intermediate Susceptible to Nonenzymatic Thiol Addition.” submitted.