Recent Publications (Past 5 years)
2023
Lippard ETC, Nemeroff CB. The Devastating Clinical Consequences of Child Abuse and Neglect: Increased Disease Vulnerability and Poor Treatment Response in Mood Disorders. Am J Psychiatry. 2023 Aug 1;180(8):548-564. doi: 10.1176/appi.ajp.19010020. PMID: 37525603.
Kirsch DE, Kosted R, Le V, Almeida JRC, Fromme K, Strakowski SM, Lippard ETC. Ventral prefrontal network response to alcohol in young adults with bipolar disorder: a within-subject randomized placebo-controlled alcohol administration study. Neuropsychopharmacology. 2023 Dec;48(13):1910-1919. doi: 10.1038/s41386-023-01657-6. Epub 2023 Jul 20. PMID: 37474761; PMCID: PMC10584851.
Kosted R, Kirsch DE, Le V, Fromme K, Lippard ETC. Subjective response to alcohol: Interactive effects of early life stress, parental risk for mood and substance use disorders, and drinking context. Pharmacol Biochem Behav. 2023 Aug;229:173591. doi: 10.1016/j.pbb.2023.173591. Epub 2023 Jun 22. PMID: 37353164.
Lippard ETC, Kirsch DE, Kosted R, Le V, Almeida JRC, Fromme K, Strakowski SM. Subjective response to alcohol in young adults with bipolar disorder and recent alcohol use: a within-subject randomized placebo-controlled alcohol administration study. Psychopharmacology (Berl). 2023 Apr;240(4):739-753. doi: 10.1007/s00213-023-06315-9. Epub 2023 Jan 25. PMID: 36695842; PMCID: PMC10084816.
2022
Kirsch DE, Le V, Kosted R, Fromme K, Lippard ETC. Neural underpinnings of expecting alcohol: Placebo alcohol administration alters nucleus accumbens resting state functional connectivity. Behav Brain Res. 2023 Feb 2;437:114148. doi: 10.1016/j.bbr.2022.114148. Epub 2022 Oct 4. PMID: 36206822.
van Velzen LS, Dauvermann MR, Colic L, Villa LM, Savage HS, Toenders YJ, Zhu AH, Bright JK, Campos AI, Salminen LE, Ambrogi S, Ayesa-Arriola R, Banaj N, Başgöze Z, Bauer J, Blair K, Blair RJ, Brosch K, Cheng Y, Colle R, Connolly CG, Corruble E, Couvy-Duchesne B, Crespo-Facorro B, Cullen KR, Dannlowski U, Davey CG, Dohm K, Fullerton JM, Gonul AS, Gotlib IH, Grotegerd D, Hahn T, Harrison BJ, He M, Hickie IB, Ho TC, Iorfino F, Jansen A, Jollant F, Kircher T, Klimes-Dougan B, Klug M, Leehr EJ, Lippard ETC, McLaughlin KA, Meinert S, Miller AB, Mitchell PB, Mwangi B, Nenadić I, Ojha A, Overs BJ, Pfarr JK, Piras F, Ringwald KG, Roberts G, Romer G, Sanches M, Sheridan MA, Soares JC, Spalletta G, Stein F, Teresi GI, Tordesillas-Gutiérrez D, Uyar-Demir A, van der Wee NJA, van der Werff SJ, Vermeiren RRJM, Winter A, Wu MJ, Yang TT, Thompson PM, Rentería ME, Jahanshad N, Blumberg HP, van Harmelen AL; ENIGMA Suicidal Thoughts and Behaviours Consortium; Schmaal L. Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium. Mol Psychiatry. 2022 Nov;27(11):4550-4560. doi: 10.1038/s41380-022-01734-0. Epub 2022 Sep 7. PMID: 36071108; PMCID: PMC9734039.
Colic L, Clark A, Sankar A, Rathi DJ, Goldman DA, Kim JA, Villa LM, Edmiston EK, Lippard ETC, Pittman B, Constable RT, Mazure CM, Blumberg HP. Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder. Eur Neuropsychopharmacol. 2022 Oct;63:35-46. doi: 10.1016/j.euroneuro.2022.07.186. Epub 2022 Aug 28. PMID: 36037590; PMCID: PMC9593266.
Tretyak V, Kirsch DE, Le V, Fromme K, Strakowski SM, Lippard ETC. Coping drinking motives, neural functional coupling during emotion processing, and alcohol use in young adults with bipolar disorder. Alcohol Clin Exp Res. 2022 Aug;46(8):1482-1496. doi: 10.1111/acer.14885. Epub 2022 Jul 22. PMID: 35702929; PMCID: PMC9478569.
Tretyak V, Huffman A, Lippard ETC. Peer victimization and associated alcohol and substance use: Prospective pathways for negative outcomes. Pharmacol Biochem Behav. 2022 Jul;218:173409. doi: 10.1016/j.pbb.2022.173409. Epub 2022 May 27. PMID: 35636587.
Kirsch DE, Tretyak V, Le V, Huffman A, Fromme K, Strakowski SM, Lippard ETC. Alcohol Use and Prefrontal Cortex Volume Trajectories in Young Adults with Mood Disorders and Associated Clinical Outcomes. Behav Sci (Basel). 2022 Feb 22;12(3):57. doi: 10.3390/bs12030057. PMID: 35323376; PMCID: PMC8945008.
Kirsch DE, Lippard ETC. Early life stress and substance use disorders: The critical role of adolescent substance use. Pharmacol Biochem Behav. 2022 Apr;215:173360. doi: 10.1016/j.pbb.2022.173360. Epub 2022 Feb 25. PMID: 35219756; PMCID: PMC8983562.
Lippard ETC, Nemeroff CB. Going beyond risk factor: Childhood maltreatment and associated modifiable targets to improve life-long outcomes in mood disorders. Pharmacol Biochem Behav. 2022 Apr;215:173361. doi: 10.1016/j.pbb.2022.173361. Epub 2022 Feb 24. PMID: 35219755.
Kirsch DE, Preston A, Tretyak V, Le V, Weber W, Strakowski SM, Lippard ETC. Neural functional connectivity changes to psychosocial stress in young adults with bipolar disorder and preliminary associations with clinical trajectories. Bipolar Disord. 2022 May;24(3):298-309. doi: 10.1111/bdi.13127. Epub 2021 Sep 24. PMID: 34532945; PMCID: PMC8926937.
2021
Le V, Kirsch DE, Tretyak V, Weber W, Strakowski SM, Lippard ETC. Recent Perceived Stress, Amygdala Reactivity to Acute Psychosocial Stress, and Alcohol and Cannabis Use in Adolescents and Young Adults With Bipolar Disorder. Front Psychiatry. 2021 Nov 15;12:767309. doi: 10.3389/fpsyt.2021.767309. PMID: 34867554; PMCID: PMC8634636.
Tretyak V, Kirsch DE, Radpour S, Weber WA, Fromme K, Strakowski SM, Lippard ETC. Subjective response to alcohol: Associated alcohol use and orbitofrontal gray matter volume in bipolar disorder. J Affect Disord. 2021 Jan 15;279:671-679. doi: 10.1016/j.jad.2020.10.046. Epub 2020 Oct 29. PMID: 33190118; PMCID: PMC7812664.
Kirsch DE, Tretyak V, Radpour S, Weber WA, Nemeroff CB, Fromme K, Strakowski SM, Lippard ETC. Childhood maltreatment, prefrontal-paralimbic gray matter volume, and substance use in young adults and interactions with risk for bipolar disorder. Sci Rep. 2021 Jan 8;11(1):123. doi: 10.1038/s41598-020-80407-w. PMID: 33420255; PMCID: PMC7794246.
2020
Lippard ETC, Weber W, Welge J, Adler CM, Fleck DE, Almeida J, DelBello MP, Strakowski SM. Variation in rostral anterior cingulate functional connectivity with amygdala and caudate during first manic episode distinguish bipolar young adults who do not remit following treatment. Bipolar Disord. 2021 Aug;23(5):500-508. doi: 10.1111/bdi.13025. Epub 2020 Nov 18. PMID: 33089593; PMCID: PMC8060357.
Jabbi M, Weber W, Welge J, Nery F, Tallman M, Gable A, Fleck DE, Lippard ETC, DelBello M, Adler C, Strakowski SM. Frontolimbic brain volume abnormalities in bipolar disorder with suicide attempts. Psychiatry Res. 2020 Dec;294:113516. doi: 10.1016/j.psychres.2020.113516. Epub 2020 Oct 22. PMID: 33160217.
Schmaal L, van Harmelen AL, Chatzi V, Lippard ETC, Toenders YJ, Averill LA, Mazure CM, Blumberg HP. Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies. Mol Psychiatry. 2020 Feb;25(2):408-427. doi: 10.1038/s41380-019-0587-x. Epub 2019 Dec 2. PMID: 31787757; PMCID: PMC6974434.
Sankar A, Purves P, Colic L, Lippard ETC, Millard H, Fan S, Spencer L, Wang F, Pittman B, Constable TR, Gross JJ, Blumberg HP. Altered Frontal Cortex Functioning in Emotion Regulation and Hopelessness in Bipolar Disorder. Bipolar Disorders, 2020, doi: 10.1111/bdi.12954 (online ahead of print), PMID: 32521570
Kirsch D, Nemeroff CM, Lippard ETC. Early life stress and substance use disorders: underlying neurobiology and pathways to adverse outcomes. Adversity and Resilience Science, 2020.
Lippard ETC, Nemeroff CB. The Devastating Clinical Consequences of Child Abuse and Neglect: Increased Disease Vulnerability and Poor Treatment Response in Mood Disorders. Am J Psychiatry. 2020 Jan 1;177(1):20-36. doi: 10.1176/appi.ajp.2019.19010020. Epub 2019 Sep 20. PMID: 31537091; PMCID: PMC6939135.
2019
Lippard ETC, Johnston JAY, Spencer L, Quatrano S, Fan S, Sankar A, Weathers J, Pittman B, Oquendo M, Blumberg HP. Gray and white matter structure and longitudinal changes in frontal systems associated with future suicide attempts in adolescents and young adults with mood disorders. Journal of Affective Disorders: 245:1139-1148, 2019. PMCID: PMC6487887
Fan S, Lippard ETC, Sankar A, Wallace A, Johnston JAY, Wang F, Pittman B, Spencer L, Oquendo MA, Blumberg HP. Grey and white matter differences in adolescents and young adults with prior suicide attempts across bipolar and major depressive disorders. Journal of Affective Disorders: 245: 1089-1097. PMCID: PMC6903411
2018
Weathers J, Lippard ETC, Spencer L, Quatrano S, Pittman B Wang F, Blumberg HP. Longitudinal diffusion tensor imaging study of adolescents and young adults with bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry (2018). PMCID: PMC5806147
2017
Lippard ETC, Jensen K, Wang F, Johnston JAY, Spencer L, Pittman B, McIntosh A, Gelernter J, Blumberg HP. Effects of ANK3 variation on gray and white matter in bipolar disorder. Molecular Psychiatry (2017). PMCID: PMC5133179
Lippard ETC, Jensen KP, Wang F, Johnston JAY, Spencer L, Pittman B, Gelernter J, Blumberg HP. Genetic variation of ANK3 is associated with lower white matter structural integrity in bipolar disorder. Molecular Psychiatry (2017).
Johnston JAY, Wang F, Liu J, Blond BN, Wallace A, Liu J, Spencer L, Cox Lippard ET, Purves KL, Landeros-Weisenberger A, Hermes E, Pittman B, Zhang S, King R, Martin A, Oquendo MA, Blumberg HP. Multimodal Neuroimaging of Frontolimbic Structure and Function Associated With Suicide Attempts in Adolescents and Young Adults With Bipolar Disorder. The American Journal of Psychiatry (2017). PMCID: PMC5939580
Lippard ET, Mazure CM, Johnston JA, Spencer L, Weathers J, Pittman B, Wang F, Blumberg HP. Brain circuitry associated with the development of substance use in bipolar disorder and preliminary evidence for sexual dimorphism in adolescents. Journal of neuroscience research (2017) 95(1-2):777-791. PMCID: PMC5123602