Publications 354. H. Wang, Z. Peng, Y. Li, J. J. Sahn, T. R. Hodges, T.-H. Chou, Q. Liu, X. Zhou, S. Jiao, V. Porciatti, D. J. Liebl, S. F. Martin, R. Wen, Sci. Rep. 2022 in review. σ2R/TMEM97 in retinal ganglion cell degeneration. Publisher’s Version 353. J. Jing, N. Arbez, J. J. Sahn, Y. Lu, K. T. Linkens, T. R. Hodges, A. Tang, R. Wiseman, S. F. Martin, and C. A. Ross, ACS Chem. Neurosci. 2022, in press. Neuroprotective Effects of σ2R/TMEM97 Receptor Modulators in Neuronal Model of Huntington’s Disease. Publisher’s Version 352. M. D. Wood, J. J. Sahn, and S. F. Martin, Eur. J. Med. Chem. 2022, 243:114696. Targeting σ2R/TMEM97 Receptors with Novel Aminotetralins. Publisher’s Version 351. G. D. Walby and S. F. Martin, Eur. J. Med. Chem. 2022, 235, 114310. Preparation and Evaluation of Sigma Receptor Binding Affinities of Novel Analogs of 2-Aryl Piperidines. Publisher’s Version 350. S. F. Martin, Acc. Chem. Res. 2022, doi.org/10.1021/acs.accounts.1c00773. Invited article. Bridging Known and Unknown Unknowns: From Natural Products and Their Mimics to Unmet Needs in Neuroscience. Publisher’s Version 349. Z. Wang and S. F. Martin, Chem. Eur. J. 2022, e202200311. Design, Synthesis and Evaluation of Novel Carbazole-Derived Photocages. Publisher’s Version 348. Z. Wang and S. F. Martin, Tetrahedron 2021, 103, 132551. Concise Stereoselective and Stereodivergent Syntheses of (±)-Melicolones A and B. invited article. Publisher’s Version 347. M. D. Wood, D. W. Klosowski, and S. F. Martin Tetrahedron 2021, 89, 132150. Tandem Vinylogous Mannich and Hetero Diels-Alder Reactions: Concise Total Synthesis of (±)-Alstoscholarisine E. invited article. Publisher’s Version 346. S. G. Quadir, S. M. Tanino, C. D. Rohl, J. J. Sahn, E. J. Yao, L. dos Reis Cruz, P. Cottone, S. F. Martin, V. Sabino, Neuropharmacol. 2021, 184, 108409. The Sigma-2 Receptor / Transmembrane protein 97 (σ2R/TMEM97) Modulator JVW-1034 Reduces Heavy Alcohol Drinking and Associated Pain States in Male Mice. Publisher’s Version 345. G. A. Abeykoon, J. J. Sahn, and S. F. Martin Tetrahedron Lett. 2021, 66, 152828. Novel Substituted Triazolo Benzodiazepine Scaffolds to Explore Chemical Space. Publisher’s Version 344. L. T. Lepovitz and S. F. Martin, J. Org. Chem. 2021, 86, 10946. Biomimetically Inspired, One-Step Synthesis of Exotine A and Exotine B; selected for special issue on natural product synthesis. Publisher’s Version 343. S. Blumberg and S. F. Martin, ARKIVOC, 2021, part v, 7. Racemic or enantioselective osmium-catalyzed dihydroxylation of olefins under near-neutral conditions. Publisher’s Version 342. Z. Wang and S. F. Martin, Org. Lett. 2020, 22, 9071. Total Syntheses of (±)-Melicolones A and B. Highlighted in SYNFACTS: Synfacts 2021, 17, 0219. Also featured in Org. Chem. Highlights: Methods for Carbocyclic Construction. Publisher’s Version 341. D. L. Cramer, J. Tian, B. Cheng, J. H. Clements, R. M. Wypych, and S. F. Martin, Eur. J. Med. Chem. 2020, 208:112771. Some Thermodynamic Effects of Varying Nonpolar Surfaces in Protein-Ligand Interactions. (PMCID: PMC7680455; PMID: 32916312). Publisher’s Version 340. L. T. Lepovitz, A. R. Meis, S. M. Thomas, J. Wiedeman, A. Pham, K. Mensa-Wilmot, and S. F. Martin, Tetrahedron 2020, 76:131086. Design, synthesis, and evaluation of novel anti-trypanosomal compounds. Publisher’s Version 339. R. M. Wypych, S. R. LaPlante, P. W. White, and S. F. Martin Eur. J. Med. Chem. 2020, 192:112195. Structure-Thermodynamics Relationships of Hepatitis C Viral NS3 Protease Inhibitors. Publisher’s Version 338. A. M. Goodnough, J. J. Sahn, and S. F. Martin Tetrahedron Lett. 2020, 61:151777. Facile Entry to Substituted 2-Arylpiperidines via an Aza-Sakurai Reaction. Publisher’s Version 337. M. D. Wood, D. W. Klosowski, and S. F. Martin Org. Lett. 2020, 22, 786. Stereoselective Synthesis of (±)-Alstoscholarisine E. Publisher’s Version 336. L. T. Lepovitz and S. F. Martin, Tetrahedron 2019, 75:130637. Diversity-Oriented Synthesis of Bioactive Azaspirocycles. Publisher’s Version 335. Vázquez-Rosa, E., Watson, M. R., Sahn, J. J., Hodges, T. R., Schroeder, R. E., Cintrón-Pérez,C. J., Shin, M.-K., Yin, T. C., Emery, J. L., Martin, S. F., Liebl, D. J., Pieper, A. A.; Neuroprotective Efficacy of a Novel Sigma 2 Receptor/TMEM97 Modulator (DKR-1677) after Traumatic Brain Injury. ACS Chem. Neurosci. 2018, 9. Publisher’s Version 334. Lepovitz, L. T. and Martin, S. F.; Biomimetically-Inspired Synthesis of Exotine A. Among top ten downloaded articles for December 2019. Org. Lett. 2018, 20, 7875. Publisher’s Version 333. Blumberg, Sean; Martin, Stephen F.; Toward the Total Synthesis of Citreamicin η: Synthesis of the Pentacyclic Core and GAB-Ring Annelation Model Studies.Tetrahedron, 2018, 57, 2733. Publisher’s Version 332. Dockendorff, Chris; Gandhi, Disha M.; Kimball, Ian H.; Eum, Kenneth S.; Rusinova, Radda; Ingólfsson, Helgi I.; Kapoor, Ruchi; Peyear, Thasin; Dodge, Matthew W.; Martin, Stephen F.; Aldrich, Richard W.; Andersen, Olaf S.; Sack, Jon T.; Synthetic analogs of the snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT) reveal that lipid bilayer perturbation does not underlie its modulation of voltage-gated potassium channels. Biochemistry, 2018, in press.Publisher’s Version 331. Klosowski, Daniel W.; Hethcox, John Caleb; Paull, Daniel H.; Fang, Chao; Donald, James R.; Shugrue, Christopher Ryan; Pansick, Andrew David; Martin, Stephen F.; Enantioselective Halolactonization Reactions using BINOL-derived Bifunctional Catalysts: Methodology, Diversification, and Applications. J. Org. Chem. 2018, 83, 5954. (Highlighted in SYNFACTS 2018, 790). Publisher’s Version 330. Hodges, Timothy R.; Benjamin, Noah; Martin, Stephen F.; Concise Approach to the Syntheses of (±)-Gliocladin C and Related Diketopiperazine Alkaloids. Tetrahedron 2018, 74, 3329. Publisher’s Version 329. Linkens, Kathryn; Schmidt, Hayden R.; Sahn, James J.: Kruse, Andrew C.; Martin, Stephen F.; Investigating Isoindoline, Tetrahydroisoquinoline, and Benzazepine Scaffolds for their s2R/Tmem97 Binding Ligands. Eur. J. Med. Chem. 2018, 151, 557-567. Publisher’s Version 328. Klosowski, Daniel W.; Martin, Stephen F.; Synthesis of (+)-Disparlure via Enantioselective Iodolactonization. Org Lett. 2018, 20, 1269. Publisher’s Version 327. Scott, Luisa L; Sahn, James J.: Ferragud, Antonio; Yen, Rachel C.; Satarasingh, Praveen N; Wood, Michael D.; Hodges, Timothy R.; Shi, Ted; Prakash, Brooke A.; Friese, Kaitlyn M.; Shen, Angela; Sabino, Valentina; Pierce, Jonathan T.; Martin, Stephen F.; Small molecule modulator of σ2R/Tmem97 reduces alcohol withdrawal-induced behaviors. Neuropsychopharmacology, 2018, 43, 1867. Publisher’s Version 326. Klosowski, Daniel W.; Martin, Stephen F.; Synthesis of Enantioenriched Cyclohexene Fragments for Kibdelone C. SynLett, 2018, 29, 430-432. (invited paper). Featured on cover of special issue of journal. Publisher’s Version 325. Ghanem, Eman; Long, S. Reid; Rodenbusch, Stacia E.; Shear, Ruth I.; Beckham, Josh T.; Procko, Kristen; DePue, Lauren; Stevenson, Keith J.; Robertus, Jon D.; Martin, Stephen; Holliday, Bradley; Jones, Richard A.; Anslyn, Eric V.; Simmons, Sarah L.; Teaching through Research: Alignment of Core Chemistry Competencies and Skills within a Multidisciplinary Research Framework.J. Chem. Ed. 2018, 95, 248-258. Publisher’s Version 324. Mondal, Sudip; Hegarty, Evan; Sahn, James J.; Scott, Luisa L.; Gökçe, Sertan K; Martin, Chris; Ghorashian, Navid; Satarasinghe, Praveen N.; Iyer, Sangeetha; Sae-Lee, Wisath; Hodges, Timothy R.; Pierce, Jonathan T.; Martin, Stephen F.; Ben-Yakar, Adela; High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 binding ligands reduce age-dependent neurodegeneration in C. elegans SC_APP model.ACS Chem. Neurosci. 2018, 9, 1014-1026. Publisher’s Version 323. Martin, Stephen F.; Natural Products and Their Mimics as Targets of Opportunity for Discovery. J. Org. Chem. 2017, 82, 10757 – 10794. Featured as ACS Editor’s Choice article for 2017. Publisher’s Version 322. Dockendorff, Chris; Gandhi, Disha; Kimball, Ian; Eum, Kenneth S.; Rusinova, Radda; Ingolfsson, Helgi; Kapoor, Ruchi; Peyear, Thasin; Martin, Stephen F.; Aldrich, Richard W.; Andersen, Olaf S.; Sack, Jon; Lipid Bilayer Perturbation by the Snail Toxin 6-Bromo-2-Mercaptotryptamine Dimer does not Account for its Modulation of Voltage-Gated Potassium Channels. Biophys. J. 2017, 112, 246A – 247A. Publisher’s Version 321. Sahn, James J.; Mejia, Galo L.; Ray, Pradipta R.; Martin, Stephen F.; Price, Theodore J.; Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice. ACS Chem. Neurosci. 2017, 8, 1801 – 1811. Publisher’s Version Featured in multiple news highlights: See Pharmafocus, September 2017, Vol 19 (7), p 8. 320. Alon, Assaf; Schmidt, Hayden R.; Wood, Michael D.; Sahn, James J.; Martin, Stephen F.; Kruse, Andrew C.; Molecular Cloning of the σ2 Receptor.” Proc. Natl. Acad. Sci (USA), 2017, 114, 7160 – 7165. Publisher’s Version Featured in PNAS Commentary: Proc. Natl. Acad. Sci (USA), 2017, 114, 6888 – 6890. Publisher’s Version 319. Hodges, Timothy R.; Benjamin, Noah; Martin, Stephen F.; Synthesis of Gliocladin C and Related Alkaloids. Org. Lett. 2017, 19, 2254 – 2257. Publisher’s Version 318. Yu, Rongrong; Chen, Xingyu; Martin, Stephen F.; Wang, Zhiqian; Differentially Substituted Phosphines via Decarbonylation of Acylphosphines. Org. Lett. 2017, 19, 1808 – 1811. Publisher’s Version 317. Sahn, James J.; Hodges, Timothy R.; Martin, Stephen F.; Norbenzomorphan Scaffold: Chemical Tool for Modulating Sigma Receptor-Subtype Selectivity. ACS Med. Chem. Lett. 2017, 8, 455 – 460. Publisher’s Version 316. Blumberg, Shawn; Martin, Stephen F.; Synthesis of the Pentacyclic Core of Citreamicin η. Org. Lett. 2017, 19, 790 – 793. Publisher’s Version 315. Yi, Bitna; Sahn, James J.; Ardestani, Pooneh M.; Evans, Andrew K.; Scott, Luisa L.; Chan, Jessica Z.; Iyer, Sangeetha, Crisp, Ashley; Zuniga Gabriella; Pierce, Jonathan T.; Martin, Stephen F.; Shamloo, Mehrdad; Small Molecule Modulator of Sigma 2 Receptor is Neuroprotective and Reduces Cognitive Deficits and Neuroinflammation in Experimental Models of Alzheimer’s Disease. J. Neurochem. 2017, 140, 561 – 575. Publisher’s Version 314. Sahn, James J.; Hodges, Timothy; Chan, Jessica Z.; Martin, Stephen F.; Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Subtype Selective Ligands. ChemMedChem. 2016, 11, 556 – 561. Publisher’s Version 313. Cheng, Bo; Sunderhaus, James D.; Martin, Stephen F.; Applications of ring closing metathesis. Total synthesis of (±)-pseudotabersonine. Tetrahedron. 2015, 71, 7323 – 7331. Publisher’s Version 312. Hethcox, J. Caleb; Shanahan, Charles S.; Martin, Stephen F.; Diastereoselective addition of monoorganocuprates to a chiral fumarate: reaction development and synthesis of (−)-dihydroprotolichesterinic acid. Tetrahedron. 2015, 71, 6361 – 6368. Publisher’s Version311. Knueppel, Daniel; Yang, Jingyue; Cheng, Bo; Mans, Douglas; Martin, Stephen F.; Total synthesis of the aglycone of IB-00208. Tetrahedron. 2015, 71, 5741 – 5757. Publisher’s Version310. Blumberg, Shawn; Martin, Stephen F.; 4-(Phenylazo)diphenylamine (PDA): a universal indicator for the colorimetric titration of strong bases, Lewis acids, and hydride reducing agents. Tetrahedron Lett. 2015, 56, 3674 – 3678. Publisher’s Version309. Yang, Jingyue; Knueppel, Daniel; Cheng, Bo; Mans, Douglas; Martin, Stephen F.; Approaches to Polycyclic 1,4-Dioxygenated Xanthones. Application to Total Synthesis of the Aglycone of IB-00208. Org. Lett. 2015, 17, 114 – 117. Publisher’s Version308. Bian, Zhiguo; Marvin, Christopher C.; Pettersson, Martin; Martin, Stephen F.; Enantioselective Total Syntheses of Citrinadins A and B. Stereochemical Revision of Their Assigned Structures. J. Am. Chem. Soc. 2014, 136, 14184 – 14192. Publisher’s Version307. Hardy, Simon; Martin, Stephen F.; Multicomponent, Mannich-type assembly process for generating novel, biologically-active 2-arylpiperidines and derivatives. Tetrahedron. 2014, 70, 7142 – 7157. Publisher’s Version306. Sahn, James J;. Granger, Brett A.; Martin, Stephen F.; Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversification. Org. Biomol. Chem. 2014, 12, 7659 – 7672. Publisher’s Version305. Myslinski, James M.; Clements, John H.; Martin, Stephen F.; Protein−ligand interactions: Probing the energetics of a putative cation−π interaction. Bioorg. Med. Chem. Lett. 2014, 24, 3164 – 3167. Publisher’s Version304. Granger, Brett A.; Jewett, Ivan T.; Butler, Jeffrey D.; Martin, Stephen F.; Concise total synthesis of (±)-actinophyllic acid. Tetrahedron. 2014, 70, 4094 – 4104. Publisher’s Version303. Martin, Stephen F.; Chapter Three – Strategies for the Synthesis of Alkaloids and Novel Nitrogen Heterocycles∗7. Adv. Heterocyclic Chem. 2013, 110, 73 – 117. Publisher’s Version302. Myslinski, James M.; Clements, John H.; DeLorbe, John E.; Martin, Stephen F.; Protein−Ligand Interactions: Thermodynamic Effects Associated with Increasing the Length of an Alkyl Chain. ACS Med. Chem. Lett. 2013, 4, 1048 – 1053. Publisher’s Version301. Granger, Brett A.; Wang, Zhiqian; Kaneda, Kyosuke; Fang, Zhenglai; Martin, Stephen F.; Multicomponent Assembly Processes for the Synthesis of Diverse Yohimbine and Corynanthe Alkaloid Analogues. ACS Comb. Sci. 2013, 15, 379 – 386. Publisher’s Version300. Granger, Brett A.; Jewett, Ivan T.; Butler, Jeffrey D.; Hua, Bruce; Knezevic, Claire E.; Parkinson, Elizabeth I.; Hergenrother, Paul J.; Martin, Stephen F.; Synthesis of (±)-Actinophyllic Acid and Analogs: Applications of Cascade Reactions and Diverted Total Synthesis. J. Am. Chem. Soc. 2013, 135, 12984 – 12986. Publisher’s Version299. Bian, Zhiguo; Marvin, Christopher C.; Martin, Stephen F.; Enantioselective Total Synthesis of (−)-Citrinadin A and Revision of Its Stereochemical Structure. J. Am. Chem. Soc. 2013, 135, 10886 – 10889. Publisher’s Version298. Shanahan, Charles S.; Fang, Chao; Paull, Daniel H.; Martin, Stephen F.; Asymmetric formal total synthesis of the stemofoline alkaloids: the evolution, development, and application of a catalytic dipolar cycloaddition cascade. Tetrahedron. 2013, 69, 7592 – 7607. Publisher’s Version297. Fu, Tsung-hao; McElroy, William T.; Shamszad, Mariam; Heidebrecht Jr., Richard W.; Gulledge, Brian; Martin, Stephen F.; Studies toward welwitindolinones: formal syntheses of N-methylwelwitindolinone C isothiocyanate and related natural products. Tetrahedron. 2013, 69, 5588 – 5603. Publisher’s Version296. Hethcox, J. Caleb; Shanahan, Charles S.; Martin, Stephen F.; Total synthesis of (−)-dihydroprotolichesterenic acid via diastereoselective conjugate addition to a chiral fumarate. Tetrahedron Lett. 2013, 54, 2074 – 2076. Publisher’s Version295. Martin, Stephen F.; Clements, John H.; Correlating Structure and Energetics in Protein-Ligand Interactions: Paradigms and Paradoxes. Annu. Rev. Biochem. 2013, 82, 267 – 293. Publisher’s Version294. Fang, Chao; Paull, Daniel H.; Hethcox, J. Caleb; Shugrue, Christopher R.; Martin, Stephen F.; Enantioselective Iodolactonization of Disubstituted Olefinic Acids Using a Bifunctional Catalyst. Org. Lett. 2012, 14, 6290 – 6293. Publisher’s Version293. Fang, Chao; Shanahan, Charles S.; Paull, Daniel H.; Martin, Stephen F.; Enantioselective Formal Total Syntheses of Didehydrostemofoline and Isodidehydrostemofoline through a Catalytic Dipolar Cycloaddition Cascade. Angew. Chem. Int. Ed. 2012, 51, 10596 – 10599. Publisher’s Version292. Sahn, James J.; Martin, Stephen F.; Expedient Synthesis of Norbenzomorphan Library via Multicomponent Assembly Process Coupled with Ring-Closing Reactions. ACS Comb. Sci. 2012, 14, 496 – 502. Publisher’s Version291. Fu, Tsung-hao; McElroy, William T.; Shamszad, Mariam; Martin, Stephen F.; Formal Syntheses of Naturally Occurring Welwitindolinones. Org. Lett. 2012, 14, 3834 – 3837. Publisher’s Version290. Paull, Daniel H.; Fang, Chao; Donald, James R.; Pansick, Andrew D.; Martin, Stephen F.; Bifunctional Catalyst Promotes Highly Enantioselective Bromolactonizations To Generate Stereogenic C−Br Bonds. J. Am. Chem. Soc. 2012, 134, 11128 – 11131. Publisher’s Version289. Nichols, Alexander L; Zhang, Patricia; Martin, Stephen F; Concise Approach to 1,4-Dioxygenated Xanthones via Novel Application of the Moore Rearrangement. Tetrahedron. 2012, 68, 7591 – 7597. Publisher’s Version288. Donald, James R.; Wood, Rebekah R.; Martin, Stephen F.; Application of a Sequential Multicomponent Assembly Process/Huisgen Cycloaddition Strategy to the Preparation of Libraries of 1,2,3-Triazole-Fused 1,4-Benzodiazepines. ACS Comb. Sci. 2012, 14, 135 – 143. Publisher’s Version287. Shi, Yue; Zhu, Crystal Z.; Martin, Stephen F.; Ren, Pengyu; Probing the Effect of Conformational Constraint on Phosphorylated Ligand Binding to an SH2 Domain Using Polarizable Force Field Simulations. J. Phys. Chem. B. 2012, 116, 1716 – 1727. Publisher’s Version286. Granger, Brett A.; Kaneda, Kyosuke; Martin, Stephen F.; Libraries of 2,3,4,6,7,11b-Hexahydro-1H-pyrido[2,1-a]isoquinolin-2-amine Derivatives via a Multicomponent Assembly Process/1,3-Dipolar Cycloaddition Strategy. ACS Comb. Sci. 2012, 14, 75 – 79. Publisher’s Version285. Donald, James R.; Granger, Brett A.; Hardy, Simon; Sahn, James J.; Martin, Stephen F.; Applications Of Multicomponent Assembly Processes To The Facile Syntheses Of Diversely Functionalized Nitrogen Heterocycles. Heterocycles. 2011, 84, 1089 – 1112. Publisher’s Version 284. Wang, Zhiqian; Kaneda, Kyosuke; Fang, Zhenglai; Martin, Stephen F.; Diversity oriented synthesis: concise entry to novel derivatives of Yohimbine and Corynanthe alkaloids. Tetrahedron Lett. 2012, 53, 477 – 479. Publisher’s Version283. Myslinski, James M.; DeLorbe, John E.; Clements, John H.; Martin, Stephen F.; Protein−Ligand Interactions: Thermodynamic Effects Associated with Increasing Nonpolar Surface Area. J. Am. Chem. Soc. 2011, 133, 18518 – 18521. Publisher’s Version282. Sahn, James J.; Martin, Stephen F.; Facile Syntheses of Substituted, Conformationally-Constrained Benzoxazocines and Benzazocines via Sequential Multicomponent Assembly and Cyclization. Tetrahedron Lett. 2011, 52, 6855 – 6858. Publisher’s Version281. Knueppel, Daniel; Martin, Stephen F.; Tandem electrocyclic ring opening/radical cyclization: application to the total synthesis of cribrostatin 6. Tetrahedron. 2011, 67, 9765 – 9770. Publisher’s Version280. Nichols, Alexander L.; Zhang, Patricia; Martin, Stephen F.; General and Expedient Synthesis of 1,4-Dioxygenated Xanthones. Org. Lett. 2011, 13, 4696 – 4699. Publisher’s Version279. Granger, Brett A.; Kaneda, Kyosuke; Martin, Stephen F.; Multicomponent Assembly Strategies for the Synthesis of Diverse Tetrahydroisoquinoline Scaffolds. Org. Lett. 2011, 13, 4542 – 4545. Publisher’s Version278. O’Keefe, B Michael; Mans, Douglas M; Kaelin, David E; Martin, Stephen F; Studies Toward the Syntheses of Pluramycin Natural Products. The First Total Synthesis of Isokidamycin. Tetrahedron. 2011, 67, 6524 – 6538. Publisher’s Version277. Shanahan, Charles S.; Fuller, Nathan O.; Ludolph, Bjoern; Martin, Stephen F.; Toward a total synthesis of the stemofoline alkaloids: advancement of a 1,3-dipolar cycloaddition strategy. Tetrahedron Lett. 2011, 52, 4076 – 4079. Publisher’s Version276. Hardy, Simon; Martin, Stephen F.; Multicomponent Assembly and Diversification of Novel Heterocyclic Scaffolds Derived from 2-Arylpiperidines. Org. Lett. 2011, 13, 3102 – 3105. Publisher’s Version275. Sahn, James J.; Su, Justin Y.; Martin, Stephen F.; Facile and Unified Approach to Skeletally Diverse, Privileged Scaffolds. Org. Lett. 2011, 13, 2590 – 2593. Publisher’s Version274. O’Keefe, B Michael; Simmons, Nicholas; Martin, Stephen F; Facile Access to Sterically Hindered Aryl Ketones via Carbonylative Cross-Coupling: Application to the Total Synthesis of Luteolin. Tetrahedron. 2011, 67, 4344 – 4351. Publisher’s273. Dietz, Jochen; Martin, Stephen F.; Novel entry to the tricyclic core of stemofoline and didehydrostemofoline. Tetrahedron Lett. 2011, 52, 2048 – 2050. Publisher’s Version272. Donald, James R.; Martin, Stephen F.; Synthesis and Diversification of 1,2,3-Triazole-Fused 1,4-Benzodiazepine Scaffolds. Org. Lett. 2011, 13, 852 – 855. Publisher’s Version271. Benjamin, Noah M.; Martin, Stephen F.; Enantioselective Synthesis of 2,2,5-Tri- and 2,2,5,5-Tetrasubstituted Tetrahydrofurans via [4 + 2] Cycloaddition and Ring-Opening Cross-Metathesis. Org. Lett. 2011, 13, 450 – 453. Publisher’s Version270. Procko, Kristen J.; Li, Hui; Martin, Stephen F.; Approach Toward the Total Synthesis of 5-Hydroxyaloin A. Org. Lett. 2010, 12, 5632 – 5635. Publisher’s Version269. O’Keefe, B. Michael; Mans, Douglas M.; Kaelin, David E.; Martin, Stephen F.; Total Synthesis of Isokidamycin. J. Am. Chem. Soc. 2010, 132, 15528 – 15530. Publisher’s Version268. DeLorbe, John E.; Clements, John H.; Whiddon, Benjamin B.; Martin, Stephen F.; Thermodynamic and Structural Effects of Macrocyclic Constraints in Protein−Ligand Interactions. ACS Med. Chem. Lett. 2010, 1, 448 – 452. Publisher’s Version267. Clements, John H.; DeLorbe, John E;. Benfield, Aaron P.; Martin, Stephen F;. Binding of flexible and constrained ligands to the Grb2 SH2 domain: structural effects of ligand preorganization. Acta Cryst. D. 2010, 66, 1101 – 1115. Publisher’s Version266. Cheng, Bo; Sunderhaus, James D.; Martin, Stephen F.; Concise Total Synthesis of (±)-Pseudotabersonine via Double Ring-Closing Metathesis Strategy. Org. Lett. 2010, 12, 3622 – 3625. Publisher’s Version265. Ward, Joshua M.; Gorenstein, Nina M.; Tian, Jianhua; Martin, Stephen F.; Post, Carol Beth; Constraining Binding Hot Spots: NMR and Molecular Dynamics Simulations Provide a Structural Explanation for Enthalpy−Entropy Compensation in SH2−Ligand Binding. J. Am. Chem. Soc. 2010, 132, 11058 – 11070. Publisher’s Version264. Deck, Jason A.; Martin, Stephen F.; Enantioselective Synthesis of (+)-Isolysergol via Ring-Closing Metathesis. Org. Lett. 2010, 12, 2610 – 2613. Publisher’s Version263. Heidebrecht, Richard W.; Gulledge, Brian; Martin, Stephen F.; Approaches to N-Methylwelwitindolinone C Isothiocyanate: Facile Synthesis of the Tetracyclic Core. Org. Lett. 2010, 12, 2492 – 2495. Publisher’s Version262. DeLorbe, John E.; Lotz, Monica D.; Martin, Stephen F.; Concise Total Synthesis of (±)-Lycopladine A. Org. Lett. 2010, 12, 1576 – 1579. Publisher’s Version261. DeLorbe, John E.; Clements, John H.; Teresk, Martin G.; Benfield, Aaron P.; Plake, Hilary R.; Millspaugh, Laura E.; Martin, Stephen F.; Thermodynamic and Structural Effects of Conformational Constraints in Protein−Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization. J. Am. Chem. Soc. 2009, 131, 16758 – 16770. Publisher’s Version260. Smith, Anna J.; Abbott, Lily K.; Martin, Stephen F.; Enantioselective Conjugate Addition Employing 2-Heteroaryl Titanates and Zinc Reagents. Org. Lett. 2009, 11, 4200 – 4203. Publisher’s Version259. Sunderhaus, James D.; Dockendorff, Chris; Martin, Stephen F.; Synthesis of Diverse Heterocyclic Scaffolds via Tandem Additions to Imine Derivatives and Ring-Forming Reactions. Tetrahedron. 2009, 65, 6454 – 6469. Publisher’s Version258. Fu, Tsung-hao; Bonaparte, Amy; Martin, Stephen F.; Synthesis of β-heteroaryl propionates via trapping of carbocations with π-nucleophiles. Tetrahedron Lett. 2009, 50, 3253 – 3257. Publisher’s Version257. Knueppel, Daniel; Martin, Stephen F.; Total Synthesis of Cribrostatin 6. Angew. Chem. Int. Ed. 2009, 48, 2569 – 2571. Publisher’s Version256. Sunderhaus, James D.; Martin, Stephen F.; Applications of Multicomponent Reactions to the Synthesis of Diverse Heterocyclic Scaffolds. Chem. Eur. J. 2009, 15, 1300 – 1308. Publisher’s Version255. Amorde, Shawn M; Jewett, Ivan T; Martin, Stephen F; Iminium Ion Cascade Reactions: Stereoselective Synthesis of Quinolizidines and Indolizidines. Tetrahedron. 2009, 65, 3222 – 3231. Publisher’s Version254. Martin, Stephen F; Recent Applications of Imines as Key Intermediates in the Synthesis of Alkaloids and Novel Nitrogen Heterocycles. Pure Appl. Chem. 2009, 81, 195 – 204. Publisher’s Version253. O’Keefe, B. Michael; Simmons, Nicholas; Martin, Stephen F.; Carbonylative Cross-Coupling of ortho-Disubstituted Aryl Iodides. Convenient Synthesis of Sterically Hindered Aryl Ketones. Org. Lett. 2008, 10, 5301 – 5304. Publisher’s Version252. Simila, Suvi T. M.; Martin, Stephen F.; Applications of the Ugi reaction with ketones. Tetrahedron Lett. 2008, 49, 4501 – 4504. Publisher’s Version251. Miller, Kenneth A.; Shanahan, Charles S.; Martin, Stephen F.; The Pauson−Khand reaction as a new entry to the synthesis of bridged bicyclic heterocycles: application to the enantioselective total synthesis of (−)-alstonerine. Tetrahedron. 2008, 64, 6884 – 6900. Publisher’s Version250. Davoren, Jennifer E.; Harcken, Christian; Martin, Stephen F.; Studies toward the Enantioselective Syntheses of Oxylipins: Total Synthesis and Structure Revision of Solandelactone E. J. Org. Chem. 2008, 73, 391 – 402. Publisher’s Version249. Ashfeld, Brandon L.; Miller, Kenneth A.; Smith, Anna J.; Tran, Kristy; Martin, Stephen F.; Features and Applications of [Rh(CO)2Cl]2-Catalyzed Alkylations of Unsymmetrical Allylic Substrates. J. Org. Chem. 2007, 72, 9018 – 9031. Publisher’s Version248. Pettersson, Martin; Knueppel, Daniel; Martin, Stephen F.; Concise, Stereoselective Approach to the Spirooxindole Ring System of Citrinadin A. Org. Lett. 2007, 9, 4623 – 4626. Publisher’s Version247. Sunderhaus, James D.; Dockendorff, Chris; Martin, Stephen F.; Applications of Multicomponent Reactions for the Synthesis of Diverse Heterocyclic Scaffolds. Org. Lett. 2007, 9, 4223 – 4226. Publisher’s Version246. Simila, Suvi T. M.; Martin, Stephen F.; Toward the Total Synthesis of FR901483: Concise Synthesis of the Azatricyclic Skeleton. J. Org. Chem. 2007, 72, 5342 – 5349. Publisher’s Version245. Sparks, Steven M.; Chen, Chi-Li; Martin, Stephen F.; Tandem intramolecular benzyne−furan cycloadditions. Total synthesis of vineomycinone B2 methyl ester. Tetrahedron. 2007, 63, 8619 – 8635. Publisher’s Version244. Breton, Philippe; Hergenrother, Paul J.; Hida, Tsuneaki; Hodgson, Anne; Judd, Andrew S.; Kraynack, Erica; Kym, Philip R.; Lee, Wen-Cherng; Loft, Michael S.; Yamashita, Masayuki; Martin, Stephen F.; Total synthesis of erythromycin B. Tetrahedron. 2007, 63, 5709 – 5729. Publisher’s Version243. Benfield, Aaron P.; Whiddon, Benjamin B.; Clements, John H.; Martin, Stephen F.; Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch. Biochem. Biophys. 2007, 462, 47 – 53. Publisher’s Version242. Benfield, Aaron P.; Goodey, Nina M.; Phillips, Lauren T.; Martin, Stephen F.; Structural studies examining the substrate specificity profiles of PC-PLCBc protein variants. Arch. Biochem. Biophys. 2007, 460, 41 – 47. Publisher’s Version241. Miller, Kenneth A.; Martin, Stephen F.; Concise, Enantioselective Total Synthesis of (−)-Alstonerine. Org. Lett. 2007, 9, 1113 – 1116. Publisher’s Version240. Martin, Stephen F.; Preorganization in biological systems: Are conformational constraints worth the energy? Pure & Appl. Chem. 2007, 79, 193 – 200. Publisher’s Version239. Davoren, Jennifer E.; Martin, Stephen F.; Enantioselective Synthesis and Structure Revision of Solandelactone E. J. Am. Chem. Soc. 2007, 129, 510 – 511. Publisher’s Version238. Chen, Chi-Li; Sparks, Steven M.; Martin, Stephen F.; C-Aryl Glycosides via Tandem Intramolecular Benzyne−Furan Cycloadditions. Total Synthesis of Vineomycinone B2 Methyl Ester. J. Am. Chem. Soc. 2006, 128, 13696 – 13697. Publisher’s Version237. Benfield, Aaron P.; Teresk, Martin G.; Plake, Hilary R.; DeLorbe, John E.; Millspaugh, Laura E.; Martin, Stephen F.; Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions. Angew. Chem. Int. Ed. 2006, 45, 6830 – 6835. Publisher’s Version236. Ashfeld, Brandon L.; Martin, Stephen F.; Enantioselective syntheses of tremulenediol A and tremulenolide A. Tetrahedron. 2006, 62, 10497 – 10506. Publisher’s Version235. Kummer, David A.; Brenneman, Jehrod B.; Martin, Stephen F.; Domino intramolecular enyne metathesis/cross metathesis approach to the xanthanolides. Enantioselective synthesis of (+)-8-epi-xanthatin. Tetrahedron. 2006, 62, 11437 – 11449. Publisher’s Version234. Deiters, Alexander; Pettersson, Martin; Martin, Stephen F.; General Strategy for the Syntheses of Corynanthe, Tacaman, and Oxindole Alkaloids. J. Org. Chem. 2006, 71, 6547 – 6561. Publisher’s Version233. Chen, Chi-Li; Martin, Stephen F.; Pd-Catalyzed Ring Opening of Oxa- and Azabicyclic Alkenes with Aryl and Vinyl Halides: Efficient Entry to 2-Substituted 1,2-Dihydro-1-naphthols and 2-Substituted 1-Naphthols. J. Org. Chem. 2006, 71, 4810 – 4817. Publisher’s Version232. Li, Hui; Procko, Kristen; Martin, Stephen F.; Facile synthesis of C-aryl glycals from sugar-derived lactones. Tetrahedron Lett. 2006, 47, 3485 – 3488. Publisher’s Version231. Simila, Suvi T. M.; Reichelt, Andreas; Martin, Stephen F.; Synthetic studies toward the immunosuppressant FR901483. Facile construction of the azatricyclic skeleton. Tetrahedron Lett. 2006, 47, 2933 – 2936. Publisher’s Version230. Reichelt, Andreas; Martin, Stephen F.; Synthesis and Properties of Cyclopropane-Derived Peptidomimetics. Acc. Chem. Res. 2006, 39, 433 – 442. Publisher’s Version229. Andrade, Rodrigo B.; Martin, Stephen F.; Formal Syntheses of (±)-Pinnaic Acid and (±)-Halichlorine. Org. Lett. 2005, 7, 5733 – 5735. Publisher’s Version228. Ashfeld, Brandon L.; Martin, Stephen F.; Enantioselective Syntheses of Tremulenediol A and Tremulenolide A. Org. Lett. 2005, 7, 4535 – 4537. Publisher’s Version227. Kummer, David A.; Brenneman, Jehrod B.; Martin, Stephen F.; Application of a Domino Intramolecular Enyne Metathesis/Cross Metathesis Reaction to the Total Synthesis of (+)-8-epi-Xanthatin. Org. Lett. 2005, 7, 4621 – 4623. Publisher’s Version226. Brenneman, Jehrod B.; Martin, Stephen F.; Ring-Closing Metathesis as a Construct for the Synthesis of Polycyclic Alkaloids. Curr. Org. Chem. 2005, 9, 1535 – 1549. Publisher’s Version225. Martin, Stephen F.; Ring-closing metathesis: A facile construct for alkaloid synthesis. Pure & Appl. Chem. 2005, 77, 1207 – 1212. Publisher’s Version224. Amorde, Shawn M.; Judd, Andrew S.; Martin, Stephen F.; Cascade Iminium Ion Reactions for the Facile Synthesis of Quinolizidines. Concise Syntheses of (±)-Epilupinine and (−)-Epimyrtine. Org. Lett. 2005, 7, 2031 – 2033. Publisher’s Version223. Antikainen, Nina M.; Martin, Stephen F.; Altering protein specificity: techniques and applications. Bioorg. Med. Chem. 2005, 13, 2701 – 2716. Publisher’s Version222. Ashfeld, Brandon L.; Miller, Kenneth A.; Smith, Anna J.; Tran, Kristy; Martin, Stephen F.; [Rh(CO)2Cl]2-Catalyzed Domino Reactions Involving Allylic Substitution and Subsequent Carbocyclization Reactions. Org. Lett. 2005, 7, 1661 – 1663. Publisher’s Version221. Chen, Chi-Li; Martin, Stephen F.; Facile Synthesis of 2-Substituted 1,2-Dihydro-1-naphthols and 2-Substituted 1-Naphthols. Org. Lett. 2004, 6, 3581 – 3584. Publisher’s Version220. Brenneman, Jehrod B.; Machauer, Rainer; Martin, Stephen F.; Enantioselective synthesis of (+)-anatoxin-a via enyne metathesis. Tetrahedron. 2004, 60, 7301 – 7314. Publisher’s Version219. Kummer, David A.; Brenneman, Jehrod B.; Martin, Stephen F.; An Efficient Synthesis of α-Branched Enones. Syn. Lett. 2004, 2004, 1431 – 1433. Publisher’s Version218. Brenneman, Jehrod B.; Martin, Stephen F.; Application of Intramolecular Enyne Metathesis to the Synthesis of Aza[4.2.1]bicyclics: Enantiospecific Total Synthesis of (+)-Anatoxin-a. Org. Lett. 2004, 6, 1329 – 1331. Publisher’s Version217. Rudolph, Alexander C.; Machauer, Rainer; Martin, Stephen F.; Synthesis of cis-2,5-disubstituted pyrrolidines via diastereoselective reduction of N-acyl iminium ions. Tetrahedron Lett. 2004, 45, 4895 – 4898. Publisher’s Version216. Ashfeld, Brandon L.; Miller, Kenneth A.; Martin, Stephen F.; Direct, Stereoselective Substitution in [Rh(CO)2Cl]2-Catalyzed Allylic Alkylations of Unsymmetrical Substrates. Org. Lett. 2004, 6, 1321 – 1324. Publisher’s Version215. Deiters, Alexander; Martin, Stephen F.; Synthesis of Oxygen- and Nitrogen-Containing Heterocycles by Ring-Closing Metathesis. Chem. Rev. 2004, 104, 2199 – 2238. Publisher’s Version214. Kaelin, David E.; Sparks, Steven M.; Plake, Hilary R.; Martin, Stephen F.; Regioselective Synthesis of Unsymmetrical C-Aryl Glycosides Using Silicon Tethers as Disposable Linkers. J. Am. Chem. Soc. 2003, 125, 12994 – 12995. Publisher’s Version213. Neipp, Christopher E.; Martin, Stephen F.; Synthesis of Bridged Azabicyclic Structures via Ring-Closing Olefin Metathesis. J. Org. Chem. 2003, 68, 8867 – 8878. Publisher’s Version212. Franklin, Christopher L.; Li, Hui; Martin, Stephen F.; Design, Synthesis, and Evaluation of Water-Soluble Phospholipid Analogues as Inhibitors of Phospholipase C from Bacillus cereus. J. Org. Chem. 2003, 68, 7298 – 7307. Publisher’s Version211. Washburn, David G.; Heidebrecht, Richard W.; Martin, Stephen F.; Concise Formal Synthesis of (−)-Peduncularine via Ring-Closing Metathesis. Org. Lett. 2003, 5, 3523 – 3525. Publisher’s Version210. Martin, Stephen F.; Handbook of Metathesis. R. H. Grubbs, Ed., Wiley-VCH, Vol. 2, p 338, 2003. “Applications of Ring Closing Metathesis to Alkaloid Synthesis”. Publisher’s Version209. Antikainen, Nina M.; Monzingo, Arthur F.; Franklin, Christopher L.; Robertus, Jon D.; Martin, Stephen F.; Using X-ray crystallography of the Asp55Asn mutant of the phosphatidylcholine-preferring phospholipase C from Bacillus cereus to support the mechanistic role of Asp55 as the general base. Arch. Biochem. Biophys. 2003, 417, 81 – 86. Publisher’s Version208. Berberich, Stephen M.; Cherney, Robert J.; Colucci, John; Courillon, Christine; Geraci, Leo S.; Kirkland, Thomas A.; Marx, Matthew A.; Schneider, Matthias F.; Martin, Stephen F.; Total synthesis of (+)-ambruticin S. Tetrahedron. 2003, 59, 6819 – 6832. Publisher’s Version207. Hergenrother, Paul J.; Hodgson, Anne; Judd, Andrew S.; Lee, Wen-Cherng; Martin, Stephen F.; An Abiotic Stategy for the Enantioselective Synthesis of Erythromycin B. Angew. Chem. Int. Ed. 2003, 42, 3278 – 3281. Angew. Chem. Int. Ed. 2003, 115, 3400 – 3403. Publisher’s Version206. Deiters, Alexander; Chen, Kevin; Eary, C. Todd; Martin, Stephen F.; Biomimetic Entry to the Sarpagan Family of Indole Alkaloids: Total Synthesis of (+)-Geissoschizine and (+)-N-Methylvellosimine. J. Am. Chem. Soc. 2003, 125, 4541 – 4550. Publisher’s Version205. Antikainen, Nina M.; Hergenrother, Paul J.; Harris, Micheleen M.; Corbett, William; Martin, Stephen F.; Altering Substrate Specificity of Phosphatidylcholine-Preferring Phospholipase C of Bacillus cereus by Random Mutagenesis of the Headgroup Binding Site. Biochemistry. 2003, 42, 1603 – 1610. Publisher’s Version204. Plake, Hilary R.; Sundberg, Thomas B.; Woodward, Angela R.; Martin, Stephen F.; Design and synthesis of conformationally constrained, extended and reverse turn pseudopeptides as Grb2-SH2 domain antagonists. Tetrahedron Lett. 2003, 44, 1571 – 1574. Publisher’s Version203. Apsel, Beth; Bender, John A.; Escobar, Maya; Kaelin Jr., David E.; Lopez, Omar D.; Martin, Stephen F.; General entries to C-aryl glycosides. Formal synthesis of galtamycinone. Tetrahedron Lett. 2003, 44, 1075 – 1077. Publisher’s Version202. Martin Stephen F.; Unified strategy for the synthesis of C-aryl glycosides. Pure & Appl. Chem. [2003, 2009], 75, 63 – 70. Publisher’s Version201. Deiters, Alexander; Martin, Stephen F.; Stereoselective Total Synthesis of Dihydrocorynantheol. Org. Lett. 2002, 4, 3243 – 3245. Publisher’s Version200. Reichelt, Andreas; Bur, Scott K.; Martin, Stephen F.; Applications of vinylogous Mannich reactions. Total synthesis of the angiotensin converting enzyme inhibitor (−)-A58365A. Tetrahedron. 2002, 58, 6323 – 6328. Publisher’s Version199. Humphrey, John M.; Liao, Yusheng; Ali, Amjad; Rein, Tobias; Wong, Yue-Ling; Chen, Hui-Ju; Courtney, Anne K.; Martin, Stephen F.; Enantioselective Total Syntheses of Manzamine A and Related Alkaloids. J. Am. Chem. Soc. 2002, 124, 8584 – 8592. Publisher’s Version198. Martin, Stephen F.; Evolution of the Vinylogous Mannich Reaction as a Key Construction for Alkaloid Synthesis. Acc. Chem. Res. 2002, 35, 895 – 904. Publisher’s Version197. Naito, Satoru; Escobar, Maya; Kym, Philip R.; Liras, Spiros; Martin, Stephen F.; Novel Approach to the Zaragozic Acids. Enantioselective Total Synthesis of 6,7-Dideoxysqualestatin H5. J. Org. Chem. 2002, 67, 4200 – 4208. Publisher’s Version196. Reichelt, Andreas; Gaul, Christoph; Frey, Robin R.; Kennedy, April; Martin, Stephen F.; Design, Synthesis, and Evaluation of Matrix Metalloprotease Inhibitors Bearing Cyclopropane-Derived Peptidomimetics as P1′ and P2′ Replacements. J. Org. Chem. 2002, 67, 4062 – 4075. Publisher’s Version195. Neipp, Christopher E.; Martin, Stephen F.; A ring-closing olefin metathesis approach to bridged azabicyclic structures. Tetrahedron Lett. 2002, 43, 1779 – 1782. Publisher’s Version194. Davidson, James P.; Lubman, Olga; Rose, Thierry; Waksman, Gabriel; Martin, Stephen F.; Calorimetric and Structural Studies of 1,2,3-Trisubstituted Cyclopropanes as Conformationally Constrained Peptide Inhibitors of Src SH2 Domain Binding. J. Am. Chem. Soc. 2002, 124, 205 – 215. Publisher’s Version193. Kirkland, Thomas A.; Colucci, John; Geraci, Leo S.; Marx, Matthew A.; Schneider, Matthias; Kaelin, David E.; Martin, Stephen F.; Total Synthesis of (+)-Ambruticin S. J. Am. Chem. Soc. 2001, 123, 12432 – 12433. Publisher’s Version192. Harcken, Christian; Martin, Stephen F.; Improved E-Selectivity in the Wittig Reaction of Stabilized Ylides with α-Alkoxyaldehydes and Sugar Lactols. Org. Lett. 2001, 3, 3591 – 3593. Publisher’s Version191. Ito, Masayuki; Clark, Cameron W.; Mortimore, Michael; Goh, Jane Betty; Martin, Stephen F.; Biogenetically Inspired Approach to the Strychnos Alkaloids. Concise Syntheses of (±)-Akuammicine and (±)-Strychnine. J. Am. Chem. Soc. 2001, 123, 8003 – 8010. Publisher’s Version190. Kaelin, David E.; Lopez, Omar D.; Martin, Stephen F.; General Strategies for the Synthesis of the Major Classes of C-Aryl Glycosides. J. Am. Chem. Soc. 2001, 123, 6937 – 6938. Publisher’s Version189. Liras, Spiros; Lynch, Christopher L.; Fryer, Andrew M.; Vu, Binh T.; Martin, Stephen F.; Applications of Vinylogous Mannich Reactions. Total Syntheses of the Ergot Alkaloids Rugulovasines A and B and Setoclavine. J. Am. Chem. Soc. 2001, 123, 5918 – 5924. Publisher’s Version188. Lee, Katherine L.; Goh, Jane Betty; Martin, Stephen F.; Novel entry to the Ergot alkaloids via ring closing metathesis. Tetrahedron Lett. 2001, 42, 1635 – 1638. Publisher’s Version187. Neipp, Christopher E.; Humphrey, John M.; Martin, Stephen F.; The Synthesis of Homoallylic Amines Utilizing a Cuprate-Based 1,2-Metalate Rearrangement. J. Org. Chem. 2001, 66, 531 – 537. Publisher’s Version186. Hillier, Michael C.; Davidson, James P.; Martin, Stephen F.; Cyclopropane-Derived Peptidomimetics. Design, Synthesis, and Evaluation of Novel Ras Farnesyltransferase Inhibitors. J. Org. Chem. 2001, 66, 1657 – 1671. Publisher’s Version185. Davidson, James P.; Martin, Stephen F.; Use of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide mimics in SH2 antagonists. Tetrahedron Lett. 2000, 41, 9459 – 9464. Publisher’s Version184. Bur, Scott K.; Martin, Stephen F.; Vinylogous Mannich Reactions: Some Theoretical Studies on the Origins of Diastereoselectivity. Org. Lett. 2000, 2, 3445 – 3447. Publisher’s Version183. Hergenrother, Paul J.; Martin, Stephen F.; in Topics in Current Chemistry, Phosphatidylcholine-Preferring Phospholipase C from B. cereus. Function, Structure, and Mechanism. Bioorganic Chemistry of Biological Signal Transduction. 2001, 211, 131 – 167. Publisher’s Version182. Fellows, Ingrid M.; Kaelin, David E.; Martin, Stephen F.; Application of Ring-Closing Metathesis to the Formal Total Synthesis of (+)−FR900482. J. Am. Chem. Soc. 2000, 122, 10781 – 10787. Publisher’s Version181. Nifantiev, Edward E.; Gratchev, Mikhail K.; Martin, Stephen F.; Regioselective monophosphorylation of glycols containing primary and secondary hydroxyl groups. Mendeleev Commun. 2000, 10, 3 – 4. Publisher’s Version180. Martin, Stephen F.; Hillier, Michael C.; Applications of Intramolecular Cyclopropanations of Chiral Secondary Allylic Diazoacetates. J. Chinese Chem. Soc. 2000, 47, 41 – 55. Publisher’s Version179. Martin, Stephen F.; Dwyer, Michael P.; Hartmann, Benoît; Knight, Kyle S.; Cyclopropane-Derived Peptidomimetics. Design, Synthesis, and Evaluation of Novel Enkephalin Analogues. J. Org. Chem. 2000, 65, 1305 – 1318. Publisher’s Version178. Martin, Stephen F.; Pitzer, Gregory E.; Solution conformations of short-chain phosphatidylcholine: Substrates of the phosphatidylcholine-preferring PLC of Bacillus cereus. Biochim. Biophys. Acta. 2000, 1464, 104 – 112. Publisher’s Version177. Martin, Stephen F.; Follows, Bruce C.; Hergenrother, Paul J.; Trotter, Bonnie K.; The Choline Binding Site of Phospholipase C (Bacillus cereus): Insights into Substrate Specificity. Biochemistry. 2000, 39, 3410 – 3415. Publisher’s Version176. Martin, Stephen F.; Follows, Bruce C.; Hergenrother, Paul J.; Franklin, Christopher L.; A Novel Class of Zinc-Binding Inhibitors for the Phosphatidylcholine-Preferring Phospholipase C from Bacillus cereus. J. Org. Chem. 2000, 65, 4509 – 4514. Publisher’s Version175. Martin, Stephen F.; DeBlanc, Ronald L.; Hergenrother, Paul J.; Determination of the Substrate Specificity of the Phospholipase D from Streptomyces chromofuscus via an Inorganic Phosphate Quantitation Assay. Anal. Biochem. 2000, 278, 106 – 110. Publisher’s Version174. Wasserman, Harry H.; Martin, Stephen F.; Yamamoto, Yoshinori; Eds., Stereoselective Carbon Bond Forming Reactions. Tetrahedron. 1999, 55, xiii. Publisher’s Version173. Martin, Stephen F.; Ed., Organic Syntheses. 1999, 76. Publisher’s Version172. Martin, Stephen F.; Lopez, Omar D.; Vinylogous Mannich reactions. Catalytic, asymmetric additions of triisopropylsilyloxyfurans to aldimines. Tetrahedron Lett. 1999, 40, 8949 – 8953. Publisher’s Version171. Martin, Stephen F.; Hom, Roy K.; Dwyer, Michael P.; Synthesis of enantiomerically pure vinylcyclopropanes by SN2′ allylic carboxylate displacements. Tetrahedron Lett. 1999, 40, 6721 – 6724. Publisher’s Version170. Martin, Stephen F.; Bur, Scott K.; Vinylogous Mannich reactions. Stereoselective formal synthesis of pumiliotoxin 251D. Tetrahedron. 1999, 55, 8905 – 8914. Publisher’s Version169. Martin, Stephen F.; Barr, Kenneth J.; Smith, Dudley W.; Bur, Scott K.; Applications of Vinylogous Mannich Reactions. Concise Enantiospecific Total Syntheses of (+)-Croomine. J. Am. Chem. Soc. 1999, 121, 6990 – 6997. Publisher’s Version168. Martin, Stephen F.; Chen, Kevin X.; Eary, C. Todd; An Enantioselective Total Synthesis of (+)-Geissoschizine. Org. Lett. 1999, 1, 79 – 82. Publisher’s Version167. Martin, Stephen F.; Hom, Roy K.; Stereoselective elaboration of side chain residues in cyclopropane-containing dipeptide isosteres. Tetrahedron Lett. 1999, 40, 2887 – 2890. Publisher’s Version166. Martin, Stephen F.; Hergenrother, Paul J.; Catalytic Cycle of the Phosphatidylcholine-Preferring Phospholipase C from Bacillus cereus. Solvent Viscosity, Deuterium Isotope Effects, and Proton Inventory Studies. Biochemistry. 1999, 38, 4403 – 4408. Publisher’s Version165. Martin, Stephen F.; Limberakis, Chris; Burgess, Laurence E.; Hartmann, Michael; Strategies for ansamycin antibiotics. asymmetric synthesis of the C(3)−C(21) subunit of herbimycin A. Tetrahedron. 1999, 55, 3561 – 3572. Publisher’s Version164. Martin, Stephen F.; Humphrey, John M.; Ali, Amjad; Hillier, Michael C.; Enantioselective Total Syntheses of Ircinal A and Related Manzamine Alkaloids. J. Am. Chem. Soc. 1999, 121, 866 – 867. Publisher’s Version163. Lynch, Vincent M.; Bur, Scott K.; Martin, Stephen F.; Spiro[1-azabicyclo[ 5.3.0]decane-6,2’(5’H)furan]-2’,10-dione; an example of kryptoracemic crystallization. Acta Cryst. 1999, C55, 622 – 624. Publisher’s Version162. Hillier, Michael C.; Martin, Stephen F.; A Conformationally Restricted ß-Strand HIV Protease Inhibitor. in Methods in Molecular Medicine. 1998, 23, 397 – 406. Publisher’s Version161. Dwyer, Michael P.; Martin, Stephen F.; Synthesis of Cyclopropane-Containing Leu-Enkephalin Analogs. in Methods in Molecular Medicine. 1998, 23, 407 – 416. Publisher’s Version160. Martin, Stephen F.; Naito, Satoru; Facile Entry to the Zaragozic Acids. Asymmetric Total Synthesis of 6,7-Dideoxysqualestatin H5. J. Org. Chem. 1998, 63, 7592 – 7593. Publisher’s Version159. Martin, Stephen F.; Hillier, Michael C.; Diastereodifferentiation in intramolecular cyclopropanations of chiral secondary allylic diazoacetates. Tetrahedron Lett. 1998, 39, 2929 – 2932. Publisher’s Version158. Martin, Stephen F.; Hergenrother, Paul J.; General Base Catalysis by the Phosphatidylcholine-Preferring Phospholipase C from Bacillus cereus: The Role of Glu4 and Asp55. Biochemistry. 1998, 37, 5755 – 5760. Publisher’s Version157. Martin, Stephen F.; Dorsey, Gordon O.; Gane, Todd; Hillier, Michael C.; Kessler, Horst; Baur, Matthias; Mathä, Barbara; Erickson, John W.; Bhat, T. Nagarajan; Munshi, Sanjeev; Gulnik, Sergei V.; Topol, Igor A.; Cyclopropane-Derived Peptidomimetics. Design, Synthesis, Evaluation, and Structure of Novel HIV-1 Protease Inhibitors. J. Med. Chem. 1998, 41, 1581 – 1597. Publisher’s Version156. Martin, Stephen F.; Hergenrother, Paul J.; Enzymatic synthesis of a modified phospholipid and its evaluation as a substrate for B. cereus phospholipase C. Bioorg. Med. Chem. Lett. 1998, 8, 593 – 596. Publisher’s Version155. Martin, Stephen F.; Dwyer, Michael P.; Iodocyclopropanes as versatile intermediates for the synthesis of substituted cyclopropanes. Tetrahedron Lett. 1998, 39, 1521 – 1524. Publisher’s Version154. Martin, Stephen F.; Dwyer, Michael P.; Lynch, Christopher L.; Application of AlMe3-mediated amidation reactions to solution phase peptide synthesis. Tetrahedron Lett. 1998, 39, 1517 – 1520. Publisher’s Version153. Martin, Stephen F.; Bur, Scott K.; The stereochemical course of intramolecular vinylogous Mannich reactions. Tetrahedron Lett. 1997, 38, 7641 – 7644. Publisher’s Version152. Hergenrother, Paul J.; Martin, Stephen F.; Determination of the Kinetic Parameters for Phospholipase C (Bacillus cereus) on Different Phospholipid Substrates Using a Chromogenic Assay Based on the Quantitation of Inorganic Phosphate. Anal. Biochem. 1997, 251, 45 – 49. Publisher’s Version151. Martin, Stephen F.; Anderson, Bruce G.; Daniel, Dilon; Gaucher, Anne; A cycloaddition approach to breynolide. Tetrahedron. 1997, 53, 8997 – 9006. Publisher’s Version150. Hergenrother, Paul J.; Haas, Michelle K.; Martin, Stephen F.; Chromogenic assay for phospholipase D from Streptomyces chromofuscus: Application to the evaluation of substrate analogs. Lipids. 1997, 32, 783 – 788. Publisher’s Version149. Martin, Stephen F.; Hida, Tsuneaki; Kym, Philip R.; Loft, Michael; Hodgson, Anne; The Asymmetric Synthesis of Erythromycin B. J. Am. Chem. Soc. 1997, 119, 3193 – 3194. Publisher’s Version148. Martin, Stephen F.; Limberakis, Chris; Diprotection of primary amines as N-substituted-2,5-bis[(triisopropylsilyl)oxy]pyrroles (BIPSOP). Tetrahedron Lett. 1997, 38, 2617 – 2620. Publisher’s Version147. Martin, Stephen F.; General strategies for the stereoselective synthesis of alkaloid natural products. Pure & Appl. Chem. 1997, 69, 571 – 576. Publisher’s Version146. Martin, Stephen F.; Wagman, Allan S.; Synthesis and Kinetic Evaluation of Inhibitors of the Phosphatidylinositol-Specific Phospholipase C from Bacillus cereus. J. Org. Chem. 1996, 61, 8016 – 8023. Publisher’s Version145. Martin, Stephen F.; Spaller, Mark R.; Hergenrother, Paul J.; Expression and Site-Directed Mutagenesis of the Phosphatidylcholine-Preferring Phospholipase C of Bacillus cereus: Probing the Role of the Active Site Glu146. Biochemistry. 1996, 35, 12970 – 12977. Publisher’s Version144. Martin, Stephen F.; Clark, Cameron W.; Ito, Masayuki; Mortimore, Michael; A Biomimetic Approach to the Strychnos Alkaloids. A Novel, Concise Synthesis of (±)-Akuammicine and a Route to (±)-Strychnine. J. Am. Chem. Soc. 1996, 118, 9804 – 9805. Publisher’s Version143. Martin, Stephen F.; Barr, Kenneth J.; Vinylogous Mannich Reactions. The Asymmetric Total Synthesis of (+)-Croomine. J. Am. Chem. Soc. 1996, 118, 3299 – 3300. Publisher’s Version142. Martin, Stephen F.; Chen, Hui-Ju; Courtney, Anne K.; Liao, Yusheng; Pätzel, Michael; Ramser, Melissa N.; Wagman, Allan S.; Ring-closing olefin meta thesis for the synthesis of fused nitrogen heterocycles. Tetrahedron. 1996, 52, 7251 – 7264. Publisher’s Version141. Martin, Stephen F.; Dodge, Jeffrey A.; Burgess, Laurence E.; Limberakis, Chris; Hartmann, Michael; Novel approach to the ansamycin antibiotics macbecin I and herbimycin A. A formal total synthesis of (+)-macbecin I. Tetrahedron. 1996, 52, 3229 – 3246. Publisher’s Version140. Doyle, Michael P.; Dyatkin, Alexey B.; Kalinin, Alexey V.; Ruppar, Daniel A.; Martin, Stephen F.; Spaller, Mark R.; Liras, Spiros; Highly selective enantiomer differentiation in intramolecular cyclopropanation reactions of racemic secondary allylic diazoacetates. J. Am. Chem. Soc. 1995, 117, 11021 – 11022. Publisher’s Version139. Hergenrother, Paul J.; Spaller, Mark R.; Haas, Michael K.; Martin, Stephen F.; Chromogenic Assay for Phospholipase C from Bacillus cereus. Anal. Biochem. 1995, 229, 313 – 316. Publisher’s Version138. Doyle, Michael P.; Austin, Richard E.; Bailey, A. Scott; Dwyer, Michael P.; Dyatkin, Alexey B.; Kalinin, Alexey V.; Kwan, Michelle M. Y.; Liras, Spiros; Oalmann, Christopher J.; Enantioselective Intramolecular Cyclopropanations of Allylic and Homoallylic Diazoacetates and Diazoacetamides Using Chiral Dirhodium(II) Carboxamide Catalysts. J. Am. Chem. Soc. 1995, 117, 5763 – 5775. Publisher’s Version137. Martin, Stephen F.; Clark, Cameron W.; Corbett, Jeffrey W.; Applications of Vinylogous Mannich Reactions. Asymmetric Synthesis of the Heteroyohimboid Alkaloids (-)-Ajmalicine, (+)-19-epi-Ajmalicine, and (-)-Tetrahydroalstonine. J. Org. Chem. 1995, 60, 3236 – 3242. Publisher’s Version136. Martin, S. F.; Assercq, J.-M.; Austin, R. E.; Dantanarayana, A. P.; Fishpaugh, J. R.; Gluchowski, C.; Guinn, D. E.; Hartmann, M.; Tanaka, T.; Wagner, R.; White, J. B.; Facile access to the ABC ring system of the taxane diterpenes via anionic oxy-Cope rearrangements. Tetrahedron. 1995, 51, 3455 – 3482. Publisher’s Version135. Martin, Stephen F.; Wagman, Allan S.; A novel approach to FR-900482 via ring forming metathesis. Tetrahedron Lett. 1995, 36, 1169 – 1170. Publisher’s Version134. Martin, Stephen F.; Chen, Hui-Ju; Lynch, Vincent M.; Asymmetric Synthesis of 1-Deoxy-8,8a-di-epi-castanospermine. J. Org. Chem. 1995, 60, 276 – 278. Publisher’s Version133. Martin, Stephen F.; Wagman, Allan S.; Zipp, G. Greg; Gratchev, Mikhail K.; General Route to Phosphonodithioic Acid Derivatives. J. Org. Chem. 1994, 59, 7957 – 7958. Publisher’s Version132. Martin, Stephen F.; Spaller, Mark R.; Liras, Spiros; Hartmann, Benoit; Enantio- and Diastereoselectivity in the Intramolecular Cyclopropanation of Secondary Allylic Diazoacetates. J. Am. Chem. Soc. 1994, 116, 4493 – 4494. Publisher’s Version131. Martin, Stephen F.; Liao, Yusheng; Chen, Hui-Ju; Pätzel, Michael; Ramser, Melissa N.; Novel route to fused nitrogen heterocycles by olefin metathesis. Tetrahedron Lett. 1994, 35, 6005 – 6008. Publisher’s Version130. Martin, Stephen F.; Lee, Wen-Cherng; Pacofsky, Gregory J.; Gist, Ricky P.; Mulhern, Thomas A.; Strategies for Macrolide Synthesis. A Concise Approach to Protected Seco-Acids of Erythronolides A and B. J. Am. Chem. Soc. 1994, 116, 4674 – 4688. Publisher’s Version129. Martin, Stephen F.; Wong, Yue-Ling; Wagman, Allan S.; Design, Synthesis, and Evaluation of Phospholipid Analogs as Inhibitors of the Bacterial Phospholipase C from Bacillus cereus. J. Org. Chem. 1994, 59, 4821 – 4831. Publisher’s Version128. Martin, Stephen F.; Josey, John A.; Wong, Yue-Ling; Dean, Daniel W.; General Method for the Synthesis of Phospholipid Derivatives of 1,2-O-Diacyl-sn-Glycerols. J. Org. Chem. 1994, 59, 4805 – 4820. Publisher’s Version127. Lynch, Vincent M.; Lee, Wen-Cherng, Martin, Stephen F.; Davis, Brian E.; A Novel Dioxabicyclo[3.3.1]nonane, A Key Intermediate in the Synthesis of Erythronolide B Seco-Acid. Acta Cryst. 1994, C50, 1467 – 1469. Publisher’s Version126. Martin, Stephen F.; Strategies for the Synthesis of Heterocyclic Natural Products. J. Heterocyclic Chem. 1994, 31, 679 – 686. Publisher’s Version125. Martin, Stephen F.; Liao, Yusheng; Wong, Yueling; Rein, Tobias; A novel approach to the asymmetric synthesis of manzamine A. Construction of the tetracyclic ABCE ring system. Tetrahedron Lett. 1994, 35, 691 – 694. Publisher’s Version124. Jacobi, Peter A.; Martin, Stephen F.; A Perspective on the Contributions to Heterocyclic Chemistry by Professor Edward C. Taylor of Princeton University. Heterocycles. 1993, 35, 1 – 31. Publisher’s Version123. Martin, Stephen F.; Liras, Spiros; Novel applications of vinylogous Mannich reactions. Total synthesis of rugulovasines A and B. J. Am. Chem. Soc. 1993, 115, 10450 – 10451. Publisher’s Version122. Martin, Stephen F.; Wagman, Allan S.; A general and efficient route to phosphorodithioate analogs of naturally occurring lipids. J. Org. Chem. 1993, 58, 5897 – 5899. Publisher’s Version121. Hansen, Sissel; Hough, Edward; Svensson, L. Anders; Wong, Yue-Ling; Martin, Stephen F.; Crystal Structure of Phospholipase C from Bacillus cereus Complexed with a Substrate Analog. J. Mol. Biol. 1993, 234, 179 – 187. Publisher’s Version120. Martin, Stephen F.; Daniel, Dilon; A novel approach to breynolide. Tetrahedron Lett. 1993, 34, 4281 – 4284. Publisher’s Version119. Martin, Stephen F.; Chen, Hui Ju; Yang, Chih Ping; Facile asymmetric syntheses of 1-deoxycastanospermine and 1-deoxy-8a-epi-castanospermine. J. Org. Chem. 1993, 58, 2867 – 2873. Publisher’s Version118. Martin, Stephen F.; Lee, Wen-Cherng; Effect of metal counterions on the stereoselectivity of aldol reactions used to assemble the seco acid backbone of erythromycin b. Tetrahedron Lett. 1993, 34, 2711 – 2714. Publisher’s Version117. Martin, Stephen F.; Oalmann, Christopher J.; Liras, Spiros; Cyclopropanes as conformationally restricted peptide isosteres. Design and synthesis of novel collagenase inhibitors. Tetrahedron. 1993, 49, 3521 – 3532. Publisher’s Version116. Martin, Stephen F.; Tso, Hsi-Hwa; Synthetic Studies on the Narciclasine Alkaloids. A Synthesis of (±)-Lycoricidine. Heterocycles. 1993, 35, 85 – 88. Publisher’s Version115. Martin, Stephen F.; Strategies and Tactics for the Synthesis of Oxygenated Natural Products. J. Nat. Prod. 1992, 55, 1718 – 1731. Publisher’s Version114. Martin, Stephen F.; Oalmann, Christopher J.; Liras, Spiros; Enantioselective, rhodium catalyzed intramolecular cyclopropanations of homoallylic diazoacetates. Tetrahedron Lett. 1992, 33, 6727 – 6730. Publisher’s Version113. Baker, William R.; Jae, Hwan-Soo; Martin, Stephen R.; Condon, Stephen L.; Stein, Herman H.; Cohen, Jerome; Kleinert, Hollis D.; Conformationally restricted peptide isosteres. 2.1 Synthesis and in vitro potency of dipeptide renin inhibitors employing a 2-alkylsulfonyl-3-phenylcyclopropane carboxamide as a P3 amino acid replacement. Bioorg. Med. Chem. Lett. 1992, 2, 1405 – 1410. Publisher’s Version112. Martin, Stephen F.; Hartmann, Michael; Josey, John A.; Diastereoselective [4+2] Cycloadditions of Acyl Nitroso Compounds. Tetrahedron Lett. 1992, 33, 3583 – 3586. Publisher’s Version111. Martin, Stephen F.; Daniel, Dilon; Cherney, Robert J.; Liras, Spiros; A convergent method for the stereoselective synthesis of trisubstituted alkenes. J. Org. Chem. 1992, 57, 2523 – 2525. Publisher’s Version110. Lynch, Vincent M.; Liao, Yusheng; Martin, Stephen F.; Davis, Brian E.; Structure of a tricyclic subunit of manzamine A. Acta Cryst. C. 1992, 48, 1703 – 1705. Publisher’s Version109. Lynch, Vincent M.; Corbett, Jeffrey W.; Martin, Stephen F.; Davis, Brian E.; Structure of a chiral intermediate in the synthesis of (+)-19-epiajmalicine. Acta Cryst. C. 1992, 48, 1878 – 1880. Publisher’s Version108. Martin, Stephen F.; Austin, Richard E.; Oalmann, Christopher J.; Baker, William R.; Condon, Stephen L.; DeLara, Ed; Rosenberg, Saul H.; Spina, Kenneth P.; Stein, Herman H.; 1,2,3-Trisubstituted cyclopropanes as conformationally restricted peptide isosteres: application to the design and synthesis of novel renin inhibitors. J. Med. Chem. 1992, 35, 1710 – 1721. Publisher’s Version107. Martin, Stephen F.; Dodge, Jeffrey A.; Burgess, Laurence E.; Hartmann, Michael; A formal total synthesis of (+)-macbecin I. J. Org. Chem. 1992, 57, 1070 – 1072. Publisher’s Version106. Martin, Stephen F.; Dean, Daniel W.; Wagman, Allan S.; A general method for the synthesis of 1,1-difluoroalkylphosphonates. Tetrahedron Lett. 1992, 33, 1839 – 1842. Publisher’s Version105. Lynch, Vincent M.; Lee, Wen-Cherng; Martin, Stephen F.; Davis, Brian E.; Structure of a protected C3-C10 subunit of erythromycin and its C8 epimer. Acta Cryst. C. 1992, 48, 1145 – 1148. Publisher’s Version104. Martin, Stephen F.; Corbett, Jeffrey W.; The Stereochemical Course of Nucleophilic Additions of 2-Trialkylsilyloxyfurans to Cyclic N-Acyliminium Ions. Synthesis. 1992, 55 – 57. Publisher’s Version103. Martin, Stephen F.; Rein, Tobias; Liao, Yusheng; Construction of the tricyclic ABC ring subunit of manzamine A via a novel intramolecular Diels-Alder reaction. Tetrahedron Lett. 1991, 32, 6481 – 6484. Publisher’s Version102. Lynch, Vincent M.; Corbett, Jeffrey W.; Martin, Stephen F.; Davis, Brian E.; Structure of a key intermediate in the synthesis of (−)-5-carboxytetrahydroalstonine and (−)-tetrahydroalstonine. Acta Cryst. C. 1991, 47, 464 – 466. Publisher’s Version101. Martin, Stephen F.; Yamashita, Masayuki; Novel macrolactonization strategy for the synthesis of erythromycin antibiotics. J. Am. Chem. Soc. 1991, 113, 5478 – 5480. Publisher’s Version100. Martin, Stephen F.; Hunter, James E.; Benage, Brigitte; Geraci, Leo S.; Mortimore, Michael; Unified strategy for synthesis of indole and 2-oxindole alkaloids. J. Am. Chem. Soc. 1991, 113, 6161 – 6171. Publisher’s Version99. Martin, Stephen F.; Zinke, Paul W.; The furan approach to oxygenated natural products. Total synthesis of (+)-KDO. J. Org. Chem. 1991, 56, 6600 – 6606. Publisher’s Version98. Martin, Stephen F.; Dodge, Jeffrey A.; Efficacious modification of the mitsunobu reaction for inversions of sterically hindered secondary alcohols. Tetrahedron Lett. 1991, 32, 3017 – 3020. Publisher’s Version97. Lynch, Vincent M.; Austin, Richard E.; Martin, Stephen F.; George, Thaddeus; Determination of the absolute configuration of a novel dipeptide isostere. Acta Cryst. C. 1991, 47, 1345 – 1347. Publisher’s Version96. Martin, Stephen F.; Guinn, Denise E.; Prelog-Djerassi Lactonic Acid. A Target for Design and Development of Stereoselective Synthetic Methods. Synthesis. 1991, 4, 245 – 262. Publisher’s Version95. Doyle, Michael P.; Pieters, Roland J.; Martin, Stephen F.; Austin, Richard E.; Oalmann, Christopher J.; Mueller, Paul; High enantioselectivity in the intramolecular cyclopropanation of allyl diazoacetates using a novel rhodium(II) catalyst. J. Am. Chem. Soc. 1991, 113, 1423 – 1424. Publisher’s Version94. Lynch, Vincent M.; Daniel, D.; Martin, Stephen F.; Davis, Brian E.; Structure of ([plus-minus sign])-3-benzyloxy-2,3,3a,7a-tetrahydrobenzo[b]thiophen-5(4H)-one 1,1-dioxide. Acta Cryst. 1991, 47, 1340 – 1342. Publisher’s Version93. Lynch, Vincent M.; Mortimore, Michael; Martin, Stephen F.; Davis, Brian E.; Structure of ([plus-minus sign])-7(S)-16-deformyl-21-oxogeissoschizine-oxindole. Acta Cryst. 1991, 47, 908 – 910. Publisher’s Version92. Lynch, Vincent M.; Zinke, Paul W.; Martin, Stephen F.; Davis, Brian E.; Structure of a key intermediate in the asymmetric synthesis of (+)-KDO. Acta Cryst. 1991, 47, 910 – 912. Publisher’s Version91. Lynch, Vincent M.; Lee, Wen-Cherng; Martin, Stephen F.; Davis, Brian E.; Structure of a fully protected seco-erythronolide B acid derivative. Acta Cryst. C. 1991, 47, 1117 – 1120. Publisher’s Version90. Baker, W. R.; Martin, S. F.; US Patent Application WO 9200972, Renin Inhibiting Compounds. Publication Date, 23 February 199289. Lynch, Vincent M.; Li, Wei; Martin, Stephen F.; Davis, Brian E.; The structure of a key intermediate in the total synthesis of dendrobine. Acta Cryst. 1991, 47, 439 – 440. Publisher’s Version88. Lynch, Vincent M.; Corbett, Jeffrey W.; Martin, Stephen F.; Davis, Brian E.; Structure of a key intermediate in the synthesis of (-)-5-carboxytetrahydroalstonine and (-)-tetrahydroalstonine. Acta Cryst. 1991, 47, 464 – 466. Publisher’s Version87. Lynch, Vincent M.; Mortimore, Michael; Martin, Stephen F.; Davis, Brian E.; The structure of ([plus-minus sign])-21-oxoisopteropodine. Acta Cryst. 1991, 47, 234 – 236. Publisher’s Version86. Martin, Stephen F.; Li, Wei; Applications of intramolecular Diels-Alder reactions to alkaloid synthesis. A formal total synthesis of (.+-.)-dendrobine. J. Org. Chem. 1991, 56, 642 – 650. Publisher’s Version85. Lynch, Vincent M.; Assercq, Jean-Marie; Martin, Stephen F.; Davis, Brian E.; The structure of (4R*,7R*)-4,10,11,11-tetramethyl-5-oxobicyclo[5.3.1]undec-1(10)en-4-carbaldehyde. Acta Cryst. 1990, 46, 2472 – 2474. Publisher’s Version84. Martin, Stephen F.; Mortimore, Michael; New methods for the synthesis of oxindole alkaloids. Total syntheses of isopteropodine and pteropodine. Tetrahedron Lett. 1990, 31, 4557 – 4560. Publisher’s Version83. Lynch, Vincent M.; Li, Wei; Martin, Stephen F.; Davis, Brian E.; Structure of the ABC ring subunit of 3-hydroxy-2-oxodendrobine. Acta Cryst. 1990, 46, 1159 – 1161. Publisher’s Version82. Lynch, Vincent M.; Li, Wei; Martin, Stephen F.; Davis, Brian E.; Dendrobine support studies. The structure of a novel 3-azatricyclo[6.2.1.04,11]undecane derivative. Acta Cryst. 1990, 46, 1155 – 1157. Publisher’s Version81. Martin, Stephen F.; Austin, Richard E.; Oalmann, Christopher J.; Stereoselective synthesis of 1,2,3-trisubstituted cyclopropanes as novel dipeptide isosteres. Tetrahedron Lett. 1990, 31, 4731 – 4734. Publisher’s Version80. Lynch, Vincent M.; Daniel, D.; Martin, Stephen F.; Davis, Brian E.; Structures of two diastereomers of the tetrahydrobenzothiophene moiety of breynolide. Acta Cryst. 1990, 46, 708 – 711. Publisher’s Version79. Lynch, Vincent M.; Fishpaugh, Jeffrey R.; Martin, Stephen F.; Davis, Brian E.; Structure of ([plus-minus sign])-(1S*,3S*)-3-hydroxy-8,11,11-trimethyl-9-oxobicyclo[5.3.1]undec-7-en-1-yl benzoate. Acta Cryst. 1990, 46, 1353 – 1355. Publisher’s Version78. Lynch, Vincent M.; Tanaka, Tetsuaki; Fishpaugh, Jeffrey R.,; Martin, Stephen F.; Davis, Brian E.; Structure of ([plus-minus sign])-(1R*,4S*,6S*)-1-benzyloxy-4,8,11,11-tetramethyl-6-phenylthiobicyclo[5.3.1]undec-7-en-3-one. Acta Cryst. 1990, 46, 1351 – 1353. Publisher’s Version77. Eaton, Hugh L.; Austin, Richard E.; Fesik, Stephen W.; Martin, Stephen F.; NMR study of the possible interaction in solution of angiotensin II with a peptide encoded by angiotensin II complementary RNA. Proc. Nat. Acad. Sci. 1989, 86, 9767 – 9769. Publisher’s Version76. Martin, Stephen F.; Azaallylic Anions: (i) Metalloenamines, in Comprehensive Organic Synthesis, Pergammon Books Limited; Oxford, Vol 2, 475, 1991.75. Lynch, Vincent M.; Daniel, D.; Martin, Stephen F.; Davis, Brian E.; The Structure of a Functionalized Tetrahydrobenzothiophene. Acta Cryst. 1989, C45, 2018 – 2020. Publisher’s Version74. Martin, Stephen F.; Cheavens, Tom H.; Synthesis of polycyclic lactams via intramolecular dipolar cycloadditions of stabilized azomethine ylides. Tetrahedron Lett. 1989, 30, 7017 – 7020. Publisher’s Version73. Martin, Stephen F.; Pacofsky, Gregory J.; Gist, Ricky P.; Lee, Wen Cherng; A concise asymmetric synthesis of the seco-acid of erythronolide B. J. Am. Chem. Soc. 1989, 111, 7634 – 7636. Publisher’s Version72. Martin, Stephen F.; Li, Wei; Stereochemical aspects of the additions of anti-selective, crotyl organometallic reagents to α-alkoxy aldehydes. J. Org. Chem. 1989, 54, 6129 – 6133. Publisher’s Version71. Martin, Stephen F.; Colapret, John A.; Dappen, Michael S.; Dupre, Brian; Murphy, Christopher J.; Application of nitrile oxide cycloadditions to a convergent, asymmetric synthesis of (+)-phyllanthocin. J. Org. Chem. 1989, 54, 2209 – 2216. Publisher’s Version70. Martin, Stephen F.; Li, Wei; General methods for alkaloid synthesis via intramolecular Diels-Alder reactions. A concise formal total synthesis of (.+-.)-dendrobine. J. Org. Chem. 1989, 54, 265 – 268. Publisher’s Version69. Martin, Stephen F.; Zinke, Paul W.; The furan approach to higher monosaccharides. A concise total synthesis of (+)-KDO. J. Am. Chem. Soc. 1989, 111, 2311 – 2313. Publisher’s Version68. Lynch, Vincent M.; Pacofsky, G. J.; Martin, Stephen F.; Davis, Brian E.; Structure of a protected C(1)-C(10) subunit of erythronolides A and B. Acta Cryst. 1989, 45, 973 – 975. Publisher’s Version67. Lynch, Vincent M.; Pacofsky, G. J.; Martin, Stephen F.; Davis, Brian E.; Structure of a protected C(1)-C(10) subunit of C(2)-epi-erythronolides A and B. Acta Cryst. 1989, 45, 1641 – 1643. Publisher’s Version66. Martin, Stephen F.; A General Strategy for the Synthesis of Members of the Amaryllidaceae Family of Alkaloids. in Studies in Natural Products Chemistry. Vol. 4. Stereoselective Synthesis (Part C). Rahman, A.-ur; Ed.; Elsevier Science Publishers, Amsterdam; 1989, 1. 65. Martin, Stephen F.; General Strategies for the Asymmetric Synthesis of Oxygenated Natural Products. in Natural Products Chemistry. Vol. 3. Rahman, A.-ur; LeQuesne, P. W., Eds.; Springer-Verlag: Berlin; 1988, p 135-153. 64. Martin, Stephen F.; Geraci, Leo S.; Concise approach to the aromatic yohimboid and protoberberine alkaloids via intramolecular Diels-Alder reactions. Tetrahedron Lett. 1988, 29, 6725 – 6728. Publisher’s Version63. Martin, Stephen F.; Yang, Chih-Ping; Laswell, William L.; Rüeger, Heinrich; Application of reductive, single electron transfer processes to the generation and cyclization of ω-unsaturated α-amino radicals. Tetrahedron Lett. 1988, 29, 6685 – 6687. Publisher’s Version62. Martin, Stephen F.; A General Strategy for the Synthesis of Biologically Active Alkaloids of the Indole Family. in Proceedings of the Fourth International Conference on Chemistry and Biotechnology of Biologically Active Natural Products, Budapest, 10 – 14 August 1987. C. Szántay, A. Gottsegen, and G. Kovács, Eds. Akadémiai Kiadó: Budapest, 1988, p. 247-263. 61. Martin, Stephen F.; Fishpaugh, Jeffrey R.; Power, John M.; Giolando, Dean M.; Jones, Richard A.; Nunn, Christine M.; Cowley, Alan H.; Structure and reactivity of novel lithium di-tert-butylphosphido(alkyl)cuprates. J. Am. Chem. Soc. 1988, 110, 7226 – 7228. Publisher’s Version60. Martin, Stephen F.; Benage, Brigitte.; Hunter, James E.; A concise strategy for the syntheses of indole alkaloids of the heteroyohimboid and corynantheioid families. Total syntheses of (.+-.)-tetrahydroalstonine, (.+-.)-cathenamine and (.+-.)-geissoschizine. J. Am. Chem. Soc. 1988, 110, 5925 – 5927. Publisher’s Version59. Lynch, Vincent M.; Li, Wei; Martin, Stephen F.; Structure of the ABC ring synthon of dendrobine. Acta Cryst. 1988, 44, 187 – 189. Publisher’s Version58. Martin, Stephen F.; Campbell, Carlton L.; Total syntheses of (.+-.)-crinine and (.+-.)-buphanisine. J. Org. Chem. 1988, 53, 3184 – 3190. Publisher’s Version57. Martin, Stephen F.; Josey, John A.; A general protocol for the preparation of phospholipids via phosphite coupling. Tetrahedron Lett. 1988, 29, 3631 – 3634. Publisher’s Version56. Martin, Stephen F.; Gluchowski, Charles; Campbell, Carlton L.; Chapman, Robert C.; A concise route to a key intermediate in the total syntheses of (+)-tirandamycic acid and (-)-tirandamycin a †0. Tetrahedron. 1988, 44, 3171 – 3180. Publisher’s Version55. Martin, Stephen F.; A Unified Approach to the Indole Alkaloids of the Yohimboid, Heteroyohimboid, and Corynantheioid Families. in Strategies and Tactics in Organic Synthesis. Vol 2. T. Lindberg, Ed.; Academic Press, New York, NY, 1989, 291-322. 54. Larson, Steven B.; Martin, Stephen F.; Williamson, Sidney A.; Structure of (3aR*,5S*,7aR*)-2,5-dimethyl-1,3,3a,4,5,6,7,7a-octahydroisoindol-1-one at 163 K. Acta Cryst. 1987, 43, 1850 – 1851. Publisher’s Version53. Lynch, V. M.,; Mulhern, T. A.,; Martin, S. F.,; Structure of an epimeric aldol intermediate toward the synthesis of erythronolide A. Acta Cryst. 1987, 43, 2237 – 2238. Publisher’s Version52. Martin, Stephen F.; Guinn, Denise E.; Stereoselective synthesis of (+)-Prelog-Djerassi lactone from furanoid intermediates. J. Org. Chem. 1987, 52, 5588 – 5593. Publisher’s Version51. Martin, Stephen F.; The Amaryllidaceae Alkaloids. in The Alkaloids, Vol. 30, A. R. Brossi, Ed.; Academic Press, New York, NY, 1987, p 251 – 376.50. Martin, Stephen F.; Dappen, Michael S.; Dupre, Brian; Murphy, Christopher J.; A convergent total synthesis of (+)-phyllanthocin. J. Org. Chem. 1987, 52, 3706 – 3708. Publisher’s Version49. Martin, Stephen F; Campbell, Carlton L; Total syntheses of (±)-crinine and (±)-buphanisine. Tetrahedron Lett. 1987, 28, 503 – 506. Publisher’s Version48. Martin, Stephen F.; Rueger, Heinrich; Williamson, Sidney A.; Grzejszczak, Slawek; General strategies for the synthesis of indole alkaloids. Total synthesis of (.+-.)-reserpine and (.+-.)-α-yohimbine. J. Am. Chem. Soc. 1987, 109, 6124 – 6134. Publisher’s Version47. Martin, Stephen F.; Davidsen, Steven K.; Puckette, Thomas A.; Total syntheses of the amaryllidaceae alkaloids (.+-.)-hemanthidine and (.+-.)-pretazettine. J. Org. Chem. 1987, 52, 1962 – 1972. Publisher’s Version46. Davidson, Steven K.; Phillips, Gerald W.; Martin, Stephen F.; Geminal Acylation- Alkylation at a Carbonyl Center Using Diethyl N-Benzylideneaminomethylphosphonate: Preparation of 2-Methyl-2-phenyl-4-pentenal. Org. Synth. 1987, 65, 119. Publisher’s Version45. Martin, Stephen F.; Benage, Brigitte; Williamson, Sidney A.; Brown, Stephen P.; Applications of the intramolecular diels-alder reactions of heterodienes to the syntheses of indole alkaloids. Tetrahedron. 1986, 42, 2903 – 2910. Publisher’s Version44. Sutko, John L.; Thompson, Lorri J.; Schlatterer, Robert G.; Lattanzio, Frank A.; Fairhurst, Allan S.; Campbell, Carlton; Martin, Stephen F.; Deslongehamps, Pierre; Ruest, Luc; Taylor, David R.; Separation and formation of ryanodine from dehydroryanodine. Preparation of tritium-labeled ryanodine. J. Label. Compd. Radiopharm. 1986, 23, 215 – 222. Publisher’s Version43. Martin, Stephen F.; Grzejszczak, Slawomir; Rueeger, Heinrich; Williamson, Sidney A.; Total synthesis of (.+-.)-reserpine. J. Am. Chem. Soc. 1985, 107, 4072 – 4074. Publisher’s Version42. Martin, Stephen F.; Rüeger, Heinrich; Total synthesis of α-yohimbine. Tetrahedron Lett. 1985, 26, 5227 – 5230. Publisher’s Version41. Martin, Stephen F.; Guinn, Denise E.; Furans as intermediates for the synthesis of oxygenated natural products. Asymmetric synthesis of Prelog-Djerassi lactone. Tetrahedron Lett. 1984, 25, 5607 – 5610. Publisher’s Version40. Martin, Stephen F.; Benage, Brigitte; Applications of intramolecular diels-alder reactions of heterodienes. Facile syntheses of the heteroyohimbine alkaloids tetrahydroalstonine and akuammigine. Tetrahedron Lett. 1984, 25, 4863 – 4866. Publisher’s Version39. Martin, Stephen F.; Davidsen, Steven K.; Total syntheses of the Amaryllidaceae alkaloids (.+-.)-haemanthidine and (.+-.)-pretazettine. J. Am. Chem. Soc. 1984, 106, 6431 – 6433. Publisher’s Version38. Martin, Stephen F.; Gluchowski, Charles; Campbell, Carlton L.; Chapman, Robert C.; Furans as intermediates for the synthesis of oxygenated natural products. A formal asymmetric synthesis of (+)-tirandamycic acid. J. Org. Chem. 1984, 49, 2512 – 2513. Publisher’s Version37. Martin, Stephen F.; Dupre, Brian; Regiochemistry of the dipolar cycloadditions of nitrile oxides to unactivated olefins. Application to the stereoselective elaboration of β-hydroxycarbonyl compounds. Tetrahedron Lett. 1983, 24, 1337 – 1340. Publisher’s Version36. Martin, Stephen F.; Williamson, Sidney A.; Gist, R. P.; Smith, Karl M.; Aspects of the intramolecular Diels-Alder reactions of some 1,3,9-trienic amides, amines, and esters. An approach to the pentacyclic skeleton of the yohimboid alkaloids. J. Org. Chem. 1983, 48, 5170 – 5180. Publisher’s Version35. Martin, Stephen F.; White, James B.; Wagner, Rolf; Alkoxide-accelerated sigmatropic rearrangements. A novel entry to the bicyclo[5.3.1]undec-7-ene system of the taxane diterpenes. J. Org. Chem. 1982, 47, 3190 – 3192. Publisher’s Version34. Martin, Stephen F.; Tu, Chihyun; Kimura, Michio; Simonsen, Stanley H.; Intramolecular [4+2] cycloadditions as a general strategy for alkaloid synthesis. A novel formal synthesis of lycorine. J. Org. Chem. 1982, 47, 3634 – 3643. Publisher’s Version33. Martin, Stephen F.; Garrison, Philip J.; General methods for alkaloid synthesis. Total synthesis of racemic lycoramine. J. Org. Chem. 1982, 47, 1513 – 1518. Publisher’s Version32. Martin, Stephen F.; Garrison, Philip J.; Synthesis and Some Reactions of Diethyl 1-Methylthio-1(Z),3-Butadienephosphonate. Synthesis. 1982, 5, 394 – 397. Publisher’s Version31. Martin, Stephen F.; White, James B.; Intramolecular photochemical [2+2] cycloadditions. Regiochemistry of the photocyclizations of some oxygen-substituted 6-allylcyclohexenones. Tetrahedron Lett. 1982, 23, 23 – 26. Publisher’s Version30. Martin, Stephen F.; Tu, Chih-Yun; General strategies for alkaloid synthesis via intramolecular [4 + 2] cycloadditions of enamides. Application to the formal total synthesis of racemic lycorine. J. Org. Chem. 1981, 46, 3763 – 3764. Publisher’s Version29. Martin, Stephen F.; Garrison, Philip J.; Total synthesis of racemic lycoramine. J. Org. Chem. 1981, 46, 3567 – 3568. Publisher’s Version28. Martin, Stephen F.; Phillips, Gerald W.; Puckette, Thomas A.; Colapret, John A.; Geminal acylation-alkylation at a carbonyl carbon via regiospecifically generated metalloenamines. J. Am. Chem. Soc. 1980, 102, 5866 – 5872. Publisher’s Version27. Martin, Stephen F.; Tu, Chih-Yun; Chou, Ta-Shue; Novel intramolecular [4 + 2] cycloaddition reactions of enamines and enamides with unactivated dienes. J. Am. Chem. Soc. 1980, 102, 5274 – 5279. Publisher’s Version26. Martin, Stephen F.; Desai, Sunil R.; Philips, Gerald W.; Miller, Anna C.; General methods for alkaloid synthesis via intramolecular [4 + 2] cycloaddition reactions of enamides. A new approach to the synthesis of Aspidosperma alkaloids. J. Am. Chem. Soc. 1980, 102, 3294 – 3296. Publisher’s Version25. Martin, Stephen F.; Methodology for the construction of quaternary carbon centers. Tetrahedron. 1980, 36, 419 – 460. Publisher’s Version24. Martin,Stephen F.; Synthesis of Aldehydes, Ketones, and Carboxylic Acids from Lower Carbonyl Compounds by C-C Coupling Reactions. Synthesis. 1979, 1979, 633 – 665. Publisher’s Version23. Martin, Stephen F.; Chou, Ta-shue; Tu, Chih-yun; Intramolecular [4+2] cycloaddition reactions of enamines and enamides. Tetrahedron Lett. 1979, 20, 3823 – 3826. Publisher’s Version22. Martin, Stephen F.; Puckette, Thomas A.; Colapret, John A.; New methods for alkaloid synthesis. Facile total syntheses of (.+-.)-O-methyljoubertiamine and (.+-.)-mesembrine. J. Org. Chem. 1979, 44, 3391 – 3396. Publisher’s Version21. Martin, Stephen F.; Desai, Sunil R.; Heteroatom-substituted butadienylphosphonium salts as reagents. A new synthesis of 2-ethoxycyclohexadienes and cyclohexenones. J. Org. Chem. 1978, 43, 4673 – 4675. Publisher’s Version20. Martin, Stephen F.; Phillips, Gerald W.; Homologation-alkylation of carbonyl compounds via regiospecifically generated metallo enamines. J. Org. Chem. 1978, 43, 3792 – 3794. Publisher’s Version19. Martin, Stephen F.; Puckette, Thomas A.; A facile synthesis of racemic O-methyljoubertiamine. Tetrahedron Lett. 1978, 19, 4229 – 4232. Publisher’s Version18. Martin, Stephen F.; Chou, Ta-shue; Facile procedure for the hydrolysis of vinyl halides to ketones. Tetrahedron Lett. 1978, 19, 1943 – 1946. Publisher’s Version17. Martin, Stephen F.; Chou, Ta-Shue; Stereoselective total synthesis of racemic acorone. J. Org. Chem. 1978, 43, 1027 – 1031. Publisher’s Version16. Martin, Stephen F.; DuPriest, T.; Reactions of allylpyrrolidine carbanions with electrophiles. A new homoenolate equivalent. Tetrahedron Lett. 1977, 18, 3925 – 3928. Publisher’s Version15. Martin, Stephen F.; Garrison, Philip J.; A facile procedure for the synthesis of α,β-unsaturated aldehydes by three carbon homologation. Tetrahedron Lett. 1977, 18, 3875 – 3878. Publisher’s Version14. Martin, Stephen F.; Desai, Sunil R.; 2-Ethoxyallylidene triphenylphosphorane. A new reagent for cyclohexenone annulation. J. Org. Chem. 1977, 42, 1664 – 1666. Publisher’s Version13. Martin, Stephen F.; Chou, Ta-Shue; Payne, Claud W.; Carbonyl homologation with α substitution. A new synthesis of 4,4-disubstituted 2-cyclopentenones. J. Org. Chem. 1977, 42, 2520 – 2523. Publisher’s Version12. Martin, Stephen F.; Moore, David R.; A new approach to the synthesis of α-alkylidene-γ-butyrolactones and Δα,β-butenolides. Tetrahedron Lett. 1976, 17, 4459 – 4462. Publisher’s Version11. Martin, Stephen F.; Carbonyl homologation with α substitution. A new approach to spiroannelation. J. Org. Chem. 1976, 41, 3337 – 3338. Publisher’s Version10. Martin, Stephen F.; Gompper, Rudolf; Facile method for the transformation of ketones into α-substituted aldehydes. J. Org. Chem. 1974, 39, 2814 – 2815. Publisher’s Version9. Taylor, Edward; Martin, Stephen; A General Method of Alkylation and Alkenylation Heterocycles. J. Am. Chem. Soc. 1974, 96, 8095 – 8102. Publisher’s Version8. Taylor, Edward C.; Chittenden, Michael L.; Martin, Stephen F.; A General Procedure for the Synthesis of Epoxy-Alkylated and Acylated Heterocycles. Heterocycles 1973, 1, 59 – 65. Publisher’s Version7. Taylor, Edward C.; Martin, Stephen F.; Preparation of Cinchona Alkaloid Intermediates. U.S. Patent No. 3,989,691. 6. Taylor, Edward C.; Martin, Stephen F.; Maki, Y.; Beardsley, G. P.; Pteridines. XXVII. New synthetic route to pteridines and 7-azapteridines. J. Org. Chem. 1973, 38, 2238 – 2240. Publisher’s Version5. Taylor, Edward C.; Martin, Stephen F.; Synthesis of some 7-aryl-6-azapteridines from 1,2,4-triazine intermediates. J. Org. Chem. 1972, 37, 3958 – 3960. Publisher’s Version4. Taylor, Edward C.; Martin, Stephen F.; Facile synthesis of quinine and related cinchona alkaloids. J. Am. Chem. Soc. 1972, 94, 6218 – 6220. Publisher’s Version3. Taylor, Edward C.; Martin, Stephen F.; Facile method for alkylation and alkenylation of heterocycles. J. Am. Chem. Soc. 1972, 94, 2874 – 2875. Publisher’s Version2. Taylor, Edward Curtis.; Martin, Stephen F.; Synthesis of as-triazines and pyrimido[4,5-e]-as-triazines (6-azapteridines). J. Org. Chem. 1970, 35, 3792 – 3795. Publisher’s Version1. Martin, Stephen F.; Castle, Raymond N.; The synthesis of lmidazo[4,5-d] pyridazines. VI. v-Triazolo[4,5-d] pyridazines, pyrazino[ 2,3-d ] pyridazines and 7H-Imidazo [4,5-d] tetrazolo[ 1,5-b] pyridazine. J. Heterocyclic Chem. 1969, 6, 93 – 98. Publisher’s Version