• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
UT Shield
Umlauf Laboratory
  • Research
  • People
  • Publications
  • Resources/Protocols
  • Opportunities
  • Support Our Research
  • Generating Bacteria that Infect Brain Tumors

    We generated a strain of the intracellular bacteria, Shigella that preferentially infects Glioblastoma brain tumor cells Read more 

    Generating Bacteria that Infect Brain Tumors
  • Altering Parenchymal/Cerebrospinal Fluid Flux

    We discovered that altering the beat frequency of ependymal cilia enhances the accumulation of chemotherapy in the brain to dramatically improve treatment of Read more 

    Altering Parenchymal/Cerebrospinal Fluid Flux
  • Targeting Neuropathologies via Blood-Brain Barrier Disruption

    We recently described using neural extra-cellular matrix (ECM) binding Variable Lymphocyte Receptors (VLRs) to target regions of Blood-Brain Barrier (BBB) disruption Read more 

    Targeting Neuropathologies via Blood-Brain Barrier Disruption

October 25, 2023, Filed Under: Lead Story

Altering Parenchymal/Cerebrospinal Fluid Flux

We discovered that altering the beat frequency of ependymal cilia enhances the accumulation of chemotherapy in the brain to dramatically improve treatment of glioblastomas (J Control Release. 2023 Oct 19:S0168-3659(23)00674-0.).

Graph on the left depicts the survival of mice bearing orthotopic brain tumors treated with an ependymal cilia inhibitor (lidocaine) and temozolomide, the standard chemotherapy used for treating brain tumors. Administering with both cilia inhibitor and temozolomide results in 100% of animals surviving tumor free. Representative images of brain slices from mice treated with different combinations of cilia inhibitor and temozolomide are shown on the right. Tumor region is labeled with a “T”.

October 25, 2023, Filed Under: Lab News

Article in The Daily Texan

The Umlauf lab’s novel schemes for drug delivery to the brain are featured in The Daily Texan!

October 9, 2023, Filed Under: Lab News

Feature in Dell Medical School Voices

The Umlauf lab is featured here in Dell Medical School Voices!

October 9, 2023, Filed Under: Lab News

Umlauf Lab receives ACS Institutional Award

Umlauf lab has received a institutional grant award from the American Cancer Society

October 9, 2023, Filed Under: Lab News

Umlauf lab receives funding from TexBio

Umlauf lab will partner with TexBio to develop intratumoral drug reservoirs!

September 4, 2023, Filed Under: Lead Story

Targeting Neuropathologies via Blood-Brain Barrier Disruption

We recently described using neural extra-cellular matrix (ECM) binding Variable Lymphocyte Receptors (VLRs) to target regions of Blood-Brain Barrier (BBB) disruption induced by neuropathologies including glioblastoma (Sci Adv. 2019 May 15;5(5):eaau4245).

May 31, 2022, Filed Under: Lab News

Please Welcome Jackie Esquivel, Chase Sanders, and Juan Villacres!

Please join me in welcoming three new members to the Umlauf Lab!

November 9, 2021, Filed Under: Lab News

Welcome Undergraduates!

University of Texas at Austin undergraduates David Park, Ashley Hoffman, and Daveraj Chakravarty have started working with the Umlauf lab to tackle unmet clinical needs!

March 22, 2021, Filed Under: Lab News

Stormie Garza, Hannah-Faith Greene, and David Li Joined the Lab!

Please join us in welcoming Stormie Garza, Hannah-Faith Greene, and David Li to the lab!

January 3, 2021, Filed Under: Lab News

Umlauf Lab has Partnered with Clayton Foundation for Research!

The Umlauf Lab has partnered with the Clayton Foundation for Research to develop drug delivery systems for treating solid tumors!

  • Page 1
  • Page 2
  • Go to Next Page »

Primary Sidebar

Recent Posts

  • Generating Bacteria that Infect Brain Tumors
  • Altering Parenchymal/Cerebrospinal Fluid Flux
  • Article in The Daily Texan
  • Feature in Dell Medical School Voices
  • Umlauf Lab receives ACS Institutional Award

Footer

DELL MEDICAL SCHOOL

DEPARTMENT OF NEUROSURGERY

CONTACT THE UMLAUF LAB

  • Email
  • Facebook
  • Instagram
  • Twitter

UT Home | Emergency Information | Site Policies | Web Accessibility | Web Privacy | Adobe Reader

© The University of Texas at Austin 2025