Yao J, Xu H, Ferrick-Kiddie EA, Nottingham RM, Wu DC, Ares M, Lambowitz AM. Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers. PloS Genet. 2024 Sep 26; 20(9):e1011416 185 (20) :3671-3688.
Cui H, Diedrich JK, Wu DC, Lim JJ, Nottingham RM, Moresco JJ, Yates JR, Blencowe BJ, Lambowitz AM, Schimmel P. Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2. Nature Cell Biology [Internet]. 25 :592–603.
 | cui_2023.pdf | 10.53 MB |
News & views highlight:
Arginyl-tRNA synthetase in inflammation. Nature Cell Biology, 25, 520-521, 2023.
Last updated on 11/15/2023
Park SK, Mohr G, Yao J, Russell R, Lambowitz AM. Group II-like Reverse Transcriptases Function in Double Strand Break Repair. Cell [Internet]. 185 (20) :3671-3688.
| park_cell_2022.pdf | 12.54 MB |
Cell Leading Edge Highlight:
Last updated on 11/15/2023
Yao J, Wu DC, Nottingham RM, Lambowitz AM. Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling. eLife [Internet].
Last updated on 09/15/2020
Lentzsch AM, Yao J, Russell R, Lambowitz AM. Template switching mechanism of a group II intron-encoded reverse transcriptase and its implications for biological function and RNA-Seq. Journal of Biological Chemistry [Internet].
| lentzsch_2019.pdf | 4.57 MB |
Last updated on 01/22/2020
Belfort M, Lambowitz AM. Group II Intron RNPs and ReverseTranscriptases: From Retroelements to Research Tools. Cold Spring Harbor Perspective in Biology [Internet].
| belfort_2019.pdf | 2.83 MB |
Last updated on 06/12/2019
Xu H, Yao J, Wu DC, Lambowitz AM. Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer-formation and bias correction. Scientific Reports [Internet]. 9 (1).
| xu_2019.pdf | 4.86 MB |
Last updated on 06/11/2019
Mohr G, Silas S, Stamos J, Makarova KS, Markham LM, Yao J, Lucas-Elio P, Sanchez-Amat A, Fire AZ, Koonin EV, et al. A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol. Cell [Internet]. (72) :700-714.
| mohr_2018.pdf | 4.33 MB |
Last updated on 06/11/2019
Boivin V, Deschamps-Francoeur G, Couture S, Nottingham RM, Bouchard-Bourelle P, Lambowitz AM. Simultaneous sequencing of coding and noncoding RNA reveals a human transcriptome dominated by a small number of highly expressed noncoding genes. RNA [Internet]. 24 (7) :950-965.
| boivin_2018.pdf | 3.85 MB |
Last updated on 07/30/2018
Mohr G, Kang SY, Park SK, Qin Y, Grohman J, Yao J, Stamos JL, Lambowitz AM. A Highly Proliferative Group IIC Intron from Geobacillus stearothermophilus Reveals New Features of Group II Intron Mobility and Splicing. Journal of Molecular Biology [Internet]. 430 (17) :2760-2783.
| mohr_kang_2018.pdf | 5.16 MB |
Last updated on 07/30/2018
