Citation: Zhang P, Guo M, Zhang YJ, Lambowitz AM, Lin YC. Real-Time Visualization of G2L4 Reverse Transcriptase in DNA Repair via Microhomology-Mediated End Joining. bioRxiv [Preprint]. 2026 Mar 17:2026.03.13.711756. doi: 10.64898/2026.03.13.711756. PMID: 41890004; PMCID: PMC13015716.

RNASET2 degrades mRNAs that protect against lipotoxicity

Citation: Shuiling Zhao, Stevens Bontemps, Ryan M. Nottingham, Jun Yao, Mariana Acuña, David E. Cohen, Alan M. Lambowitz, Jean E. Schaffer, Molecular Metabolism, Vol 110, 2026, 102409, ISSN 2212-8778, https://doi.org/10.1016/j.molmet.2026.102409.

Pervasive enhanced transcription in inflammatory breast cancer tumors and PBMCs impacts RNA splicing and intronic RNAs in plasma

Citation: Dennis Wylie et al. ,Pervasive enhanced transcription in inflammatory breast cancer tumors and PBMCs impacts RNA splicing and intronic RNAs in plasma.Sci. Adv.12, eadu0031(2026).DOI:10.1126/sciadv.adu0031

Structural basis for the evolution of a domesticated group II intron–like reverse transcriptase to function in host cell DNA repair

Tagged With: 2025

Citation: Park SK, Guo M, Stamos JL, Wantae K, Lee S, Zhang YJ, Lambowitz AM. Structural basis of the evolution of a domesticated group II intron-like reverse transcriptase to function in host cell DNA repair. Biochemistry. 2025 July 29; 12231):e2504208122. Download Citation

Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers

Tagged With: 2024

Citation: Yao J, Xu H, Ferrick-Kiddie EA, Nottingham RM, Wu DC, Ares M, Lambowitz AM. Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers. PloS Genet. 2024 Sep 26; 20(9):e1011416 185 (20) :3671-3688. Download Citation

Lambowitz Lab

Department of Molecular Biosciences

The b-cytochromes of plant mitochondria. A spectrophotometric and potentiometric study.

The interaction of redox mediators with the ‘second phosphorylation site’; significance for the cytochrome bT hypothesis.

On the lack of ATP-induced midpoint potential shift for cytochrome b-566 in plant mitochondria.

The mitochondrial beta-cytochromes of the wild type and poky strains of Neurospora crassa. Evidence for a component reduced only by dithionite.

The effect of antimycin on the b-cytochromes of plant mitochondria. Oxidation-reduction behavior of cytochrome b-566.

The electron transport components of wild type and poky strains of Neurospora crassa.

Electron transport in Neurospora mitochondria. Studies on wild type and poky.

Effect of pyrrolnitrin on electron transport and oxidative phosphorylation in mitochondria isolated from Neurospora crassa.

Oxidative phosphorylation in Neurospora mitochondria. Studies on wild type, poky, and chloramphenicol-induced wild type.

Cyanide-resistant respiration in Neurospora crassa.