Citation:
Saldanha R, Chen B, Wank H, Matsuura M, Edwards J, Lambowitz AM. RNA and protein catalysis in group II intron splicing and mobility reactions using purified components. Biochemistry. 38 (28) :9069-83.
Publications
Group II intron mobility in yeast mitochondria: target DNA-primed reverse transcription activity of aI1 and reverse splicing into DNA transposition sites in vitro.
Citation:
Yang J, Mohr G, Perlman PS, Lambowitz AM. Group II intron mobility in yeast mitochondria: target DNA-primed reverse transcription activity of aI1 and reverse splicing into DNA transposition sites in vitro. J Mol Biol. 282 (3) :505-23.
Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination.
Citation:
Cousineau B, Smith D, Lawrence-Cavanagh S, Mueller JE, Yang J, Mills D, Manias D, Dunny G, Lambowitz AM, Belfort M. Retrohoming of a bacterial group II intron: mobility via complete reverse splicing, independent of homologous DNA recombination. Cell. 94 (4) :451-62.
A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: biochemical demonstration of maturase activity and insertion of new genetic information within the intron.
Citation:
Matsuura M, Saldanha R, Ma H, Wank H, Yang J, Mohr G, Cavanagh S, Dunny GM, Belfort M, Lambowitz AM. A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: biochemical demonstration of maturase activity and insertion of new genetic information within the intron. Genes Dev. 11 (21) :2910-24.
Characterization of Neurospora mitochondrial group I introns reveals different CYT-18 dependent and independent splicing strategies and an alternative 3′ splice site for an intron ORF.
Citation:
Wallweber GJ, Mohr S, Rennard R, Caprara MG, Lambowitz AM. Characterization of Neurospora mitochondrial group I introns reveals different CYT-18 dependent and independent splicing strategies and an alternative 3′ splice site for an intron ORF. RNA. 3 (2) :114-31.
De novo and DNA primer-mediated initiation of cDNA synthesis by the mauriceville retroplasmid reverse transcriptase involve recognition of a 3′ CCA sequence.
Citation:
Chen B, Lambowitz AM. De novo and DNA primer-mediated initiation of cDNA synthesis by the mauriceville retroplasmid reverse transcriptase involve recognition of a 3′ CCA sequence. J Mol Biol. 271 (3) :311-32.
The Mauriceville retroplasmid reverse transcriptase initiates cDNA synthesis de novo at the 3′ end of tRNAs.
Citation:
Chiang CC, Lambowitz AM. The Mauriceville retroplasmid reverse transcriptase initiates cDNA synthesis de novo at the 3′ end of tRNAs. Mol Cell Biol. 17 (8) :4526-35.
Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing.
Citation:
Eskes R, Yang J, Lambowitz AM, Perlman PS. Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing. Cell. 88 (6) :865-74.
Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA.
Citation:
Guo H, Zimmerly S, Perlman PS, Lambowitz AM. Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA. EMBO J. 16 (22) :6835-48.
Analysis of the CYT-18 protein binding site at the junction of stacked helices in a group I intron RNA by quantitative binding assays and in vitro selection.
Citation:
Saldanha R, Ellington A, Lambowitz AM. Analysis of the CYT-18 protein binding site at the junction of stacked helices in a group I intron RNA by quantitative binding assays and in vitro selection. J Mol Biol. 261 (1) :23-42.
