January 8, 2024, Filed Under: NewsRegister to The Oskar Fisher Lecture Series Featuring Keynote, Karen Duff, Ph.D: “Tangles: Unravelling What We Don’t Know About Tau”. Feb 8 2024. Thursday, February 8, 2024 12-1 p.m. (CDT) AT&T Executive Education and Conference Center 1900 University Avenue Austin, TX Lunch will be provided for in person attendees. Please note any dietary restrictions when registering. Dessert reception with Professor Duff will follow the in-person event. The Oskar Fischer Lecture Series features invited scholars working at the vanguard of new ideas on the mechanisms, diagnosis and treatment of dementing illnesses. The 10th lecture of the series will feature Karen Duff, Ph.D. Professor Duff is the Centre Director of the UK Dementia Research Institute at University College London and Professor Emerita at the Department of Pathology at Columbia University Medical Center, New York. Professor Duff explores disease mechanisms and tests therapeutic approaches to Alzheimer’s disease, frontotemporal disorders and other dementias. Her current interests are exploring the mechanisms involved in the spread of pathogenic proteins within the brain, understanding the basis of selective cellular vulnerability and resilience to tauopathy and developing new mouse and cell models to understand the earliest stages in tau pathogenesis. His discovery that defective genes encoding presenilins are a cause of familial AD led to presenilins becoming a new target for treatments. He went on to show that mutated presenilins contribute to the generation of the amyloid beta protein — deposition of which is the earliest sign of AD in those carrying such genes. His work on several other neurodegeneration-related genes and proteins (including SORLA, TREM2, FUS) has led to an understanding of the role of vesicular transport, inflammation and perturbed RNA granule biology. Read full bio Learn more and register The February Oskar Fischer Lecture is hosted in partnership with the 2024 TARCC Scientific Symposium. If you have registered to attend the symposium, you do not need to register for the Oskar Fischer Lecture. If you are not attending the 2024 TARCC Scientific Symposium and would like to attend The Oskar Fischer Lecture Series, please register using the button above. This event has in-person and virtual attendance options. Registration is required to receive the livestream link.
