UT Shield

Natividad Lab

Publications

  1. Vozella, V., Cruz, B., Natividad, L.A., Benvenuti, F., Cannella, N., Edwards, S., Zorrilla, E.P., Ciccocioppo, R., Roberto, M. (2021). Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats. International Journal of Molecular Sciences, 22(6):3095. doi: 10.3390/ijms22063095.
  2. Natividad, L.A., Steinman, M.Q., McGinn, M.A., Sucheschandra, S., Kerr, T.M., Ciccocioppo, R., Messaoudi, I., Edwards, S., Roberto, M. (2021). Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically-selected Marchigian Sardinian Alcohol-preferring rats. Addiction Biology, 26(3):e12978. doi: 10.1111/adb.12978.
  3. Agoglia, A.E., Zhu, M., Ying, R., Sidhu, H., Natividad, L.A., Wolfe, S.A., Buczynski, M.W., Contet, C., Parsons, L.H., Roberto, M., Herman, M.A. (2020). Corticotropin releasing factor receptor-1 neurons in the lateral amygdala display selective sensitivity to acute and chronic ethanol exposure. eNeuro, 7(2):ENEURO.0420-19.2020.
  4. Suarez, J., Khom, S., Alen, F., Natividad, L.A., Varodayan, F.P., Patel, R.R., Kirson, D., Arco, R., Ballesta, A., Bajo, M., Rubio, L., Martín-Fardon, R., Rodríguez de Fonseca, F., Roberto, M. (2020). Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala. Addiction Biology, 25(5):e12813.
  5. Natividad, L.A.*, Buczynski, M.W.*, McClatchy D.B., Yates, J.R. (2018). From synapse to function: a perspective on the role of neuroproteomics in elucidating mechanisms of drug addiction. Proteomes, 6(4):50.
  6. Stopponi, S., Fotio, Y., Domi, A., Borruto, A.M., Natividad, L., Roberto M., Ciccocioppo, R., Cannella, N. (2018). Inhibition of fatty acid amide hydrolase in the central amygdala alleviates comorbid expression of innate anxiety and excessive alcohol intake. Addiction Biology, 23(6):1223-1232.
  7. Carcoba, L.M., Flores, R.J., Natividad, L.A., O’Dell, L.E. (2018). Amino acid modulation of dopamine in the nucleus accumbens mediates sex differences in nicotine withdrawal. Addiction Biology, 23(5):1046-1054.
  8. Natividad, L.A.*, Steinman, M.Q.*, Laredo, S.A., Irimia, C., Polis, I.Y., Lintz, R., Buczynski, M.W., Martin-Fardon, R., Roberto, M., Parsons, L.H. (2018). Phosphorylation of calcium/calmodulin-dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol-induced cognitive inflexibility. Addiction Biology, 23(5):1117-1129.
  9. Serrano, A., Pavon, F.J., Buczynski, M.W., Schlosburg, J., Natividad, L.A., Polis, I.Y., Stouffer, D., Zorrilla, E.P., Roberto, M., Rodriguez de Fonseca, F., Cravatt, B.F., Martin-Fardon, R., Parsons, L.H. (2018). Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake. Neuropsychopharmacology, 43(9):1840-1850.
  10. Natividad, L.A., Buczynski, M.W., Herman, M.A., Kirson, D., Oleata, C.S., Irimia, C., Polis, I., Ciccocioppo, R., Roberto, M., Parsons, L.H. (2017). Constitutive increases in amygdalar corticotropin-releasing factor and fatty acid amide hydrolase drive an anxious phenotype. Biological Psychiatry, 82(7):500-510.
  11. Irimia, C., Buczynski, M.W., Natividad, L.A., Laredo, S.A., Avalos, N., Parsons, L.H. (2017). Dysregulated glycine signaling contributes to increased impulsivity during protracted alcohol abstinence. Journal of Neuroscience, 37(7):1853-1861.
  12. Buczynski M.W., Herman M.A., Hsu K.L., Natividad L.A., Irimia C., Polis I.Y., Pugh H., Chang J.W., Niphakis M.J., Cravatt B.F., Roberto M., Parsons L.H. (2016). Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences, 113(4):1086-91.
  13. Irimia, C., Wiskerke, J., Natividad, L.A., Polis, I.Y., de Vries, T.J., Pattij, T., Parsons, L.H. (2015). Increased impulsivity in rats as a result of repeated cycles of alcohol intoxication and abstinence. Addiction Biology, 20(2):263-274.
  14. O’Dell, L.E., Natividad, L.A., Pipkin, J.A., Roman, F., Torres, I., Jurado, J., Torres, O.V., Friedman, T.C., Tenayuca, J.M., Nazarian, A. (2014). Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction Biology, 19(6):1006-19.
  15. Carcoba, L.M., Orfila, J.E., Natividad, L.A., Torres, O.V., Pipkin, J.A., Castañeda, E., Moss, D.E., O’Dell, L.E. (2014). Cholinergic transmission during nicotine withdrawal is influenced by age and pre-exposure to nicotine: Implications for teenage smoking. Developmental Neuroscience, 36(3-4):347-355.
  16. Natividad, L.A., Torres, O.V., Friedman, T.C., O’Dell, L.E. (2013). Adolescence is a period of development characterized by short- and long-term vulnerability to the rewarding effects of nicotine and reduced sensitivity to the anorectic effects of this drug. Behavioural Brain Research, 257:275-285.
  17. Torres, O.V., Gentil, L.G., Natividad, L.A., Carcoba, L.M., O’Dell, L.E. (2013). Behavioral, biochemical, and molecular indices of stress are enhanced in female versus male rats experiencing nicotine withdrawal. Frontiers in Psychiatry, 4:38.
  18. Natividad, L.A., Buczynski, M.W., Parsons, L.H., Torres, O.V., O’Dell, L.E. (2012). Adolescent rats are resistant to adaptations in excitatory and inhibitory mechanisms that modulate mesolimbic dopamine during nicotine withdrawal. Journal of Neurochemistry, 123(4):578-588.
  19. Tejeda, H.A.*, Natividad, L.A.*, Orfila, J. E., Torres, O.V., O’Dell, L.E. (2012). Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner. Psychopharmacology, 224(2):289-301.
  20. Natividad, L.A., Tejeda, H.A., Torres, O.V., O’Dell, L.E. (2010). Nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats. Synapse, 64(2):136-145.
  21. Torres, O.V., Natividad, L.A., Tejeda, H.A., Van Weelden, S.A., O’Dell, L.E. (2009). The rewarding and aversive effects of nicotine in female rats are age-, hormone-, and sex-dependent. Psychopharmacology, 206(2):303-12.
  22. Torres, O.V., Tejeda, H.A., Natividad, L.A., O’Dell, L.E. (2008). Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development. Pharmacology, Biochemistry and Behavior, 90: 658-663.
  23. O’Dell, L.E., Torres, O.V., Natividad, L.A., Tejeda, H.A. (2007). Adolescent nicotine exposure produces less affective measures of withdrawal relative to adult nicotine exposure in male rats. Neurotoxicolgy and Teratology, 29(1): 17-22.

(*) Authors who contributed equally.

×