Most up to date list: Latest Check out our most recent critical review: Melbourne, J.K., Chandler, C.M., Van Doorn, C., Pauly, J.R., Bardo, M.T., Peng, H., & Nixon, K. (2021). Primed for addiction: A critical review of the role of microglia in the neurodevelopmental consequences of adolescent alcohol drinking. Invited Critical Review for Alcoholism: Clinical & Experimental Research, 45(10): 1908-1926; 10.1111/acer.14694. PMC8793635. Select data papers: Peng, H., Harvey, B.T., Richards, C.I., & Nixon, K. (2021). Neuron-Derived Extracellular Vesicles Modulate Microglia Activation and Function. Invited submission to special issue Extracellular Vesicles: Multifaceted Biological Nanoparticles in Health and Disease, Meena Kumari (Ed.), Biology, 10(10): 948; 10.3390/biology10100948. PMC8533634. Nawarawong, N.N., Thompson, K.R., Guerin, S.G., Peng, H., & Nixon, K. (2021). Reactive, adult neurogenesis from increased neural stem cell proliferation following alcohol dependence in female rats. New Insights into Adult Neurogenesis and Neurodegeneration: Challenges for Brain Repair, J.A. Morales-Garcia, N. Kaneko, V. Herranz-Pérez (Eds.), Frontiers in Neuroscience, 15: 689601; 10.3389/fnins.2021.689601. PMC8477003. Nawarawong, N.N.†, Nickell, C.G.†, Hopkins, D.M., Pauly J.R., & Nixon K. (2021). Functional Activation of Newborn Neurons Following Alcohol-Induced Reactive Neurogenesis. Invited submission to Neurogenesis and Gliogenesis in Health and Disease, Chitra Mandyam and Hiyaa Ghosh (Eds.), Brain Sciences, 11(4): 499; 10.3390/brainsci11040499. PMC8071556. †authors contributed equally. Peng, H., & Nixon, K. (2021). Microglia Phenotypes Following the Induction of Alcohol Dependence in Adolescent Rats. Alcoholism: Clinical & Experimental Research, 5(1): 105-116; 10.1111/acer.14504. PMC8296648. Nickell, C.G.†, Thompson, K.R.†, Pauly, J.R., & Nixon, K. (2020). Recovery of hippocampal-dependent learning despite blunting reactive adult neurogenesis after alcohol dependence. Brain Plasticity, 6(1): 83-101; 10.3233/BPL-200108. PMC7903006. †authors contributed equally. Marshall, S.A.†, McClain, J.A.†, Wooden, J.I., & Nixon, K. (2020). Microglia dystrophy following binge-like alcohol exposure in adolescent and adult male rats. Frontiers in Neuroanatomy, 14: 52; 10.3389/fnana.2020.00052. PMC7439004. †authors contributed equally Nixon, K., & Mangieri, R.A. (2019). Compelled to drink: Why some cannot stop. Science, 366(6468): 947-948; 10.1126/science.aaz7357. PMC exempt. Hayes, D.M., Nickell, C.G., Chen, K.Y., Heath, M.M., McClain, J.A., Deeny, M.A., & Nixon, K. (2018). Activation of neural stem cells from quiescence drives reactive hippocampal neurogenesis after alcohol dependence. Neuropharmacology, 133: 276-288; 10.1016/j.neuropharm.2018.01.032. PMC6620048. Nickell, C.R.G., Peng, H., Hayes, D.M., Chen, K., McClain, J.A., & Nixon, K. (2017). Type 2 neural progenitor cell activation drives reactive neurogenesis after binge-like alcohol exposure in adolescent, male rats. Invited submission for special issue on adolescence, Frontiers in Psychiatry, 8: 283; 10.3389/fpsyt.2017.00283. PMC5736541. Liput, D.J., Pauly, J.R., Stinchcomb, A.L., & Nixon, K. (2017). Binge alcohol exposure transiently changes the endocannabinoid system: a potential target to prevent alcohol-induced neurodegeneration. Alcohol neurotoxicology special issue, M. Prendergast (Ed.), Brain Sciences, 7(12): 158-176; 10.3390/brainsci7120158. PMC5742761. Peng, H., Nickell, C.R.G., Chen, K.Y., McClain, J.A., & Nixon K. (2017). Increased expression of M1 and M2 phenotypic markers in isolated microglia after four-day binge alcohol exposure in male rats. Alcohol, 62: 29-40; 10.1016/j.alcohol.2017.02.175. PMC5695703. Marshall, S.A., Geil, C.R., & Nixon, K. (2016). Prior binge ethanol exposure potentiates the microglial response in a model of alcohol-induced neurodegeneration. Neuroimmunology special issue, Donna Gruol (Guest Ed.), Brain Sciences, 6(2): 16-35; 10.3390/brainsci6020016. PMC4931493. Liput, D.J., Tsakalozou, E., Hammell, D.C., Paudel, K., Nixon, K., & Stinchcomb, A.L. (2014). Quantification of anandamide, oleoylethanolamide and palmitoylethanolamide in rodent brain tissue using high performance liquid chromatography – electrospray mass spectroscopy. Journal of Pharmaceutical Analysis, 4(4): 234–24; 10.1016/j.jpha.2013.11.004. PMC4260322. McClain, J.A., Morris, S.A., & Nixon, K. (2014). Ectopic hippocampal neurogenesis in adolescent rats following alcohol dependence. Addiction Biology, 19(4): 687-99; 10.1111/adb.12075. PMC3844012. Liput, D.J., Hammell, D.C., Deeny, A., Stinchcomb, A.L., & Nixon, K. (2013). Transdermal delivery of cannabidiol attenuates alcohol-induced neurodegeneration in a rat model of alcohol abuse. Pharmacology, Biochemistry & Behavior, 111: 120-127; 10.1016/j.pbb.2013.08.013. PMC4096899. Marshall, S.A., McClain, J.A., Kelso, M.L., Hopkins, D.M., Pauly, J.R., & Nixon, K. (2013). Microglial activation is not equivalent to neuroinflammation: the importance of microglia phenotype in alcohol-induced neurodegeneration. Neurobiology of Disease, 54: 239-251; 10.1016/j.nbd.2012.12.016. PMC3629000. Kelso, M.L., Liput, D.J., Eaves, D.W., & Nixon, K. (2011). Upregulation of vimentin suggests novel areas of neurodegeneration in a rodent model of an alcohol use disorder. Neuroscience, 197: 381-393; 10.1016/j.neuroscience.2011.09.019. PMC3298440. McClain, J.A., Hayes, D.M., Morris, S.A., & Nixon, K. (2011). Adolescent binge alcohol exposure alters hippocampal progenitor cell proliferation in rats: Effects on cell cycle kinetics. Journal of Comparative Neurology, 519(13): 2697-2710; 10.1002/cne.22647. PMC3454493. McClain, J.A., Morris, S.A., Deeny, M.A., Marshall, S.A., Hayes, D.M., Kiser, Z.M., & Nixon, K. (2011). Adolescent binge alcohol exposure induces long-lasting partial activation of microglia. Supplemental Issue to Celebrate the 40th Anniversary of the National Institute on Alcohol Abuse and Alcoholism, Brain Behavior and Immunity, 25(Suppl 1): S120–S128; 10.1016/j.bbi.2011.01.006. PMC3098298. Leasure, J.L., & Nixon, K. (2010). Exercise neuroprotection in a rat model of binge alcohol consumption. Alcoholism: Clinical and Experimental Research, 34(3): 404-414; 10.1111/j.1530-0277.2009.01105.x. PMC2936244. Morris, S.A., Kelso, M.L., Liput, D.J., Marshall, S.A., & Nixon, K. (2010). Similar withdrawal severity in adolescents and adults in a rat model of alcohol dependence. Special issue on adolescence, D.B. Matthews (Ed.), Alcohol, 44(1): 89-98; 10.1016/j.alcohol.2009.10.017. PMC2818405. Morris, S.A., Eaves, D.W., Smith, A.R., & Nixon, K. (2010). Alcohol inhibition of adult neurogenesis – a mechanism of hippocampal neurodegeneration in an adolescent alcohol abuse model. Hippocampus, 20(5): 596-607; 10.1002/hipo.20665. PMC2861155. Nixon, K., Kim, D.H., Potts, E.N., He, J., & Crews, F.T. (2008). Distinct cell proliferation events during abstinence after alcohol dependence: microglia proliferation precedes neurogenesis. Neurobiology of Disease, 31(2): 218-229; 10.1016/j.nbd.2008.04.009. PMC2680247. Nixon, K. (2006). Alcohol and adult neurogenesis: Roles in neurodegeneration and recovery from chronic alcoholism. Invited review, Hippocampus, 16(3): 287-295; 10.1002/hipo.20162. PMC exempt. Nixon, K. & Crews, F.T. (2004). Temporally specific burst in cell proliferation increases hippocampal neurogenesis in protracted abstinence from alcohol. The Journal of Neuroscience, 24(43): 9714-9722; 10.1523/JNEUROSCI.3063-04.2004. PMC6730141. Nixon, K. & Crews, F.T. (2002). Binge alcohol exposure decreases neurogenesis in adult rat hippocampus. Journal of Neurochemistry, 83(5): 1087-1093; 10.1046/j.1471-4159.2002.01214.x. PMC exempt. Book Chapters: Wooden, J.I., Thompson, K.R., Guerin, S.P., Nawarawong, N.N., & Nixon, K. (2021). Consequences of adolescent alcohol use on adult hippocampal neurogenesis and hippocampal integrity. Invited mini-review to Effects of peri-Adolescent Licit and Illicit Drug Use on the Developing CNS, R.L. Bell and S. Rahman (Eds.), International Review of Neurobiology, 160: 281-304; 10.1016/bs.irn.2021.08.005. Melbourne, J.K., Thompson, K.R., Peng H., & Nixon, K. (2019). It’s complicated: The relationship between alcohol and microglia in the search for novel pharmacotherapeutic targets for alcohol use disorders. Shafiqur Rahman (Ed.), Molecular Basis of Neuropsychiatric Disorders: from Bench to Bedside, Progress in Molecular Biology and Translational Science, 167: 179-221. Academic Press (Elsevier; Cambridge, MA); 10.1016/bs.pmbts.2019.06.011. Olsufka, R., Peng, H., Newton, J., & Nixon, K. (2018). Alcohol Effects on Adult Neural Stem Cells – A Novel Mechanism of Neurotoxicity and Recovery in Alcohol Use Disorders. In T. Rasmussen (Ed.) Stem Cells in Birth Defects Research and Developmental Toxicology. pp173-222. John Wiley & Sons (New York, NY). Wagner, J. L., Barton, E.A., Geil, C.R., Leasure, J.L., & Nixon, K. (2016). The role of neural stem cells in alcohol use disorders. In A. K. Shetty (Ed.) Neural Stem Cells in Health and Disease. pp259-285. World Scientific Publishing Company (Singapore); 10.1142/9789814623186_0010. Nixon, K., Pauly, J.R., & Hayes, D.M. (2011). Alcohol, nicotine and adult neurogenesis. In M. Foster Olive (Ed.) Drug Addiction and Adult Neurogenesis. pp95-120. Research Signpost (Kerala, India). Nixon, K., & Morris, S.A. (2008). Neural stem cells: A potential mechanism in alcoholic neurodegeneration and recovery. In L. Sher (Ed.) Research on the Neurobiology of Alcohol Use Disorders. pp219-238. Nova Science Publishers (New York, NY). |