A warm welcome to the 5 new undergraduates who are starting their work in the lab this summer!
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Structural Basis for Target Discrimination and Activation by Cas13d
Citation: Chou, C. W., Sinan, S., Kuo, H. C., Arguello, C., Sahaya, D., Russell, R., & Finkelstein, I. J. (2025). Structural basis for target discrimination and activation by Cas13d. bioRxiv. https://doi.org/10.1101/2025.09.12.675955
Cas12a domain flexibility guides R-loop formation and forces RuvC resetting
Citation: Strohkendl, I., Saha, A., Moy, C., Nguyen, A. H., Ahsan, M., Russell, R., Palermo, G., & Taylor, D. W. (2024). Cas12a domain flexibility guides R-loop formation and forces RuvC resetting. Molecular cell, 84(14), 2717–2731.e6. https://doi.org/10.1016/j.molcel.2024.06.007