Citation:
Thirumalai, D. ; Klimov, D. K. Intermediates and transition states in protein folding. Methods Mol Biol 350, 277-303.
Download Citation
2007
Mechanical unfolding of RNA: from hairpins to structures with internal multiloops.
Citation:
Hyeon, C. ; Thirumalai, D. Mechanical unfolding of RNA: from hairpins to structures with internal multiloops. Biophys J 92, 731-43.
Download
Last updated on 08/18/2017
Charge density of divalent metal cations determines RNA stability.
Citation:
Koculi, E. ; Hyeon, C. ; Thirumalai, D. ; Woodson, S. A. Charge density of divalent metal cations determines RNA stability. J Am Chem Soc 129, 2676-82.
Download
Last updated on 08/18/2017
Coupling between allosteric transitions in GroEL and assisted folding of a substrate protein.
Citation:
Stan, G. ; Lorimer, G. H. ; Thirumalai, D. ; Brooks, B. R. Coupling between allosteric transitions in GroEL and assisted folding of a substrate protein. Proc Natl Acad Sci U S A 104, 8803-8.
Download
 | coupling-between-allosteric-transitions-in-groel-and-assisted-folding-of-a-substrate-protein.pdf | 1.89 MB |
Last updated on 08/18/2017
Interactions between hydrophobic and ionic solutes in aqueous guanidinium chloride and urea solutions: lessons for protein denaturation mechanism.
Citation:
O’Brien, E. P. ; Dima, R. I. ; Brooks, B. ; Thirumalai, D. Interactions between hydrophobic and ionic solutes in aqueous guanidinium chloride and urea solutions: lessons for protein denaturation mechanism. J Am Chem Soc 129, 7346-53.
Download
Last updated on 08/18/2017
Monomer adds to preformed structured oligomers of Abeta-peptides by a two-stage dock-lock mechanism.
Citation:
Nguyen, P. H. ; Li, M. S. ; Stock, G. ; Straub, J. E. ; Thirumalai, D. Monomer adds to preformed structured oligomers of Abeta-peptides by a two-stage dock-lock mechanism. Proc Natl Acad Sci U S A 104, 111-6.
Download
Last updated on 08/18/2017
Allosteric communication in dihydrofolate reductase: signaling network and pathways for closed to occluded transition and back.
Citation:
Chen, J. ; Dima, R. I. ; Thirumalai, D. Allosteric communication in dihydrofolate reductase: signaling network and pathways for closed to occluded transition and back. J Mol Biol 374, 250-66.
Download
Last updated on 08/18/2017
Allosteric transitions in the chaperonin GroEL are captured by a dominant normal mode that is most robust to sequence variations.
Citation:
Zheng, W. ; Brooks, B. R. ; Thirumalai, D. Allosteric transitions in the chaperonin GroEL are captured by a dominant normal mode that is most robust to sequence variations. Biophys J 93, 2289-99.
Download CitationDownload
Last updated on 08/18/2017
Effects of crowding and confinement on the structures of the transition state ensemble in proteins.
Citation:
Cheung, M. S. ; Thirumalai, D. Effects of crowding and confinement on the structures of the transition state ensemble in proteins. J Phys Chem B 111, 8250-7.
Download
Last updated on 08/18/2017
Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations.
Citation:
Mickler, M. ; Dima, R. I. ; Dietz, H. ; Hyeon, C. ; Thirumalai, D. ; Rief, M. Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations. Proc Natl Acad Sci U S A 104, 20268-73.
Download
Last updated on 01/02/2018
