Research Interests
Work in the Gore Laboratory focuses on the neuroendocrine control of reproduction, and connections among hormones, brain sexual differentiation, and behavior. Current research seeks to understand how prenatal exposure to environmental endocrine disruptors (EDCs) causes molecular epigenetic modifications and cellular changes to the developing hypothalamus and the manifestations of these effects later in life, and transgenerationally. We also have a longstanding interest in brain aging and menopause, and how hormones such estrogens affect molecular and cellular properties of the brain. Our team uses a variety of techniques, including behavioral, physiological, neuroanatomical, immunohistochemical (light and electron microscopy), and molecular (gene expression, epigenetic profiling) approaches.
See also: On Campus Feature Q&A with Dr. Gore
2017 Texas Student Research Showdown
FINALISTS!
“Inheritance of EDC effects”
Min Ji and Lexi study the ways that endocrine-disrupting chemicals effect individuals and their offspring.
Watch the video
“Inheritance of EDC effects”
Min Ji and Lexi study the ways that endocrine-disrupting chemicals effect individuals and their offspring.
Watch the video
Endocrine-disrupting chemicals”
Watch the video
Images from Left to Right: A) Gore & Dickerson (2012), Endocrine Disruptors and the Developing Brain. Morgan & Claypool. B) Walker & Gore (2011), Nature Reviews Endocrinology 7: 197 (modified). C) Gore et al. (2014) Endocrine Reviews 35: 961 (with permission). D) GnRH immunofluorescence in the median eminence of the hypothalamus. 3V, third ventricle. Weiling Yin, unpublished.
