Research Interests in the Gore Lab
Our work focuses on the neuroendocrine control of reproduction, and connections among hormones, brain sexual differentiation, and behavior. Current research seeks to understand how prenatal exposure to environmental endocrine disruptors (EDCs) causes molecular epigenetic modifications and cellular changes to the developing hypothalamus and the manifestations of these effects later in life, and transgenerationally. We also have a longstanding interest in brain aging and menopause, and how hormones such estrogens affect molecular and cellular properties of the brain. Our team uses a variety of techniques, including behavioral, physiological, neuroanatomical, immunohistochemical (light and electron microscopy), and molecular (gene expression, epigenetic profiling) approaches.
Publications
