Publications – The Dynamic Medical Image and Computing Lab

Italics indicate lab members.

Recent Publications

1. Amanda Nowacki, Leonardo Ramirez-Mireles, Allan Barcena, Anna Marks, Steven Huang, Edward Castillo and Marites Melancon. Computational Frontiers in Arteriovenous Fistula Maturation: A Review of Fluid Dynamics and Machine Learning Models. Journal of the American Society of Nephrology. In Press, 2026.

2. Joshua Joseph, Aaron Luong, Debarghya Chaki, Jasmine Jung, Yi-Kuan Liu, Amanda Nowacki, Blake Evans, Hairong Wang, and Edward Castillo. Computationally Efficient Decoupled Momentum Optimization Algorithm for Medical Imaging Models. Scientific Reports. In Press, 2026.

3. Hsu-Ting Kuo, Yi-Kuan Liu, Debarghya Chaki, Girish Nair, Danielle Turner-Lawrence, Craig Stevens, Jorge Cisneros and Edward Castillo. Diagnoses of Pulmonary Embolism from Non-Contrast 4DCT Using Image Processing-Derived Quantitative Perfusion Scores. npj Biomedical Innovations. 3:29, 2026.

4. Yi-Kuan Liu, Hsu-Ting Kuo, Alaa Melek, Richard Castillo, Yevgeniy Vinogradskiy, Lili Zhao, Girish Nair and Edward Castillo. Predicting Ventilation from Single Breathing Phase Non-Contrast CT Using Swin Transformers. Medical Physics. 54:e70406, 2026.

5. Jorge Cisneros, Caleb J. Herrera, Yi-Kuan Liu, Lisa V. Du, Yevgeniy Vinogradskiy, Richard Castillo, Girish Nair, and Edward Castillo. Clinical Validation of Perfusion Imaging with Pulmonary Function Test Data Using Voronoi-Based Discretization. Physics in Medicine and Biology. 71:055004, 2026.

6. Aaron Luong, Dominic Bolinas, Allan John Barcena, Marites Melancon, Edward Castillo, Gouthami Chintalapani, Bruno Odisio, Yun Shin Chun, Hop S. Tran Cao, Timothy E. Newhook, Ching-Wei D. Tzeng, Sanjay Gupta, Jean-Nicolas Vauthey, Steven Y. Huang. Two-Dimensional Venogram Following Portal Venous Embolization as a Predictor for Future Liver Remnant Hypertrophy. Clinical Imaging. 131:110737, 2026.

7. Girish Nair, Faizan Faizee, Zachary Smith, Sayf Al-Katib, Nadia Ashrafi, Ali Yilmaz, Romana Ashrafi Mimi, Sarayu Bhogoju, Vilija Lomeikaite, Juozas Gordevicius, Edward Castillo and Stewart Graham. Distinct Metabolic Signatures Linked to High-Resolution Computed Tomography Radiographic Phenotypes in Stable and Progressive Fibrotic Lung Disease. Metabolites. 16(1):82, 2026.

Highlights

Yi-Kuan Liu, Jorge Cisneros, Girish Nair, Craig Stevens, Richard Castillo, Yevgeniy Vinogradskiy, and Edward Castillo. Perfusion Estimation from Dynamic Non-Contrast Computed Tomography Using Unsupervised Learning and a Physics-Inspired U-Net Transformer Architecture. International Journal of Computer Assisted Radiology and Surgery. 20: 959-970, 2025.

Gabriela Roque Oliveira Nomura, Aaron Luong, Ananya Prakash, Annabelle Alemand, Tanish Bhowmick, Alisa Ali, Jaimie Ren, Basil Rehani, Girish Nair, Richard Castillo, Yevgeniy Vinogradskiy, and Edward Castillo. TriSwinUNETR Lobe Segmentation Model for Computing DIR-Free CT-Ventilation. Frontiers in Oncology, 15: 1475133, 2025.

Yevgeniy Vinogradskiy, Richard Castillo, Edward Castillo, Leah Schubert, Bernard Jones, Austin Faught, Laurie Gaspar, Jennifer Kwak, Daniel Bowles, Timothy Waxweiler, Jing Jingjing Dougherty, Dexiang Gao, Craig Stevens, Moyed Miften, Brian Kavanagh, Inga Grills, Chad Rusthoven, and Thomas Guerrero. Results of a Multi-Institutional Phase II Clinical Trial for 4DCT-Ventilation Functional Avoidance Thoracic Radiotherapy. International Journal of Radiation Oncology, Biology, Physics, 112(4): 986-995, 2022.

Edward Castillo, Girish Nair, Danielle Turner-Lawrence, Nicholas Myziuk, Scott Emerson, Sayf Al-Katib, Sarah Westergaard, Richard Castillo, Yevgeniy Vinogradskiy, Thomas Quinn, Thomas Guerrero, and Craig Stevens. Quantifying Pulmonary Perfusion from Non-Contrast Computed Tomography. Medical Physics, 48: 1804-1814, 2021.

Edward Castillo, Yevgeniy Vinogradskiy, and Richard Castillo. Robust HU-Based CT-Ventilation from an Integrated Mass Conservation Formulation. Medical Physics, 46(11): 5036-5046, 2019. (Editor’s Choice Featured Article)

Edward Castillo, Richard Castillo, Yevgeniy Vinogradskiy, Michele Dougherty, David Solis, Nicholas Myziuk, Andrew Thompson, Rudy Guerra, Girish Nair, and Thomas Guerrero. Robust CT-Ventilation from the Integral Formulation of the Jacobian. Medical Physics, 46(5): 2115-2125, 2019. (Editor’s Choice Featured Article, Issue Cover Article)

Edward Castillo, Richard Castillo, Yevgeniy Vinogradskiy, and Thomas Guerrero. The Numerical Stability of Transformation-Based CT Ventilation. International Journal of Computer Assisted Radiology and Surgery, 12(4): 569-580, 2017.

Edward Castillo, Richard Castillo, Josue Martinez, Maithili Shenoy, and Thomas Guerrero. Four Dimensional Deformable Image Registration Using Trajectory Modeling. Physics in Medicine and Biology, 55: 305-327, 2010.

Richard Castillo, Edward Castillo, Rudy Guerra, Valen Johnson, Travis McPhail, Amit Garg, and Thomas Guerrero. A Framework for Evaluation of Deformable Image Registration Spatial Accuracy Using Large Landmark Point Sets. Physics in Medicine and Biology, 54: 1849-1870, 2009. (PMB Featured Article 2009)