Selected publications

24. Soto MR, Lewis MM, Leal J, Pan Y, Mohanty RP, Peng X, Dong T, Ghosh G. Discovery of peptides for targeted delivery of mRNA lipid nanoparticles to cystic fibrosis lung epithelia. 2023.

23. Lewis MM, Soto MR, Maier EY, Wulfe SD, Bakheet S, Obregon H, Ghosh D. Optimization of ionizable lipids for aerosolizable mRNA lipid nanoparticles. Bioengineering & Translational Medicine, e10580, 2023.

22. Zhang H, Leal J, Soto MR, Smyth HDC, Ghosh D. Aerosolizable lipid nanoparticles for pulmonary delivery of mRNA through design of experiments. 12:1042, 2020. doi-org.ezproxy.lib.utexas.edu/10.3390/pharmaceutics12111042

21. Mohanty RP, Liu X, Ghosh D. Electrostatic Driven Transport Enhances Penetration of Positively Charged Peptide Surfaces through Tumor Extracellular Matrix. Acta Biomaterialia, 113:240-251, 2020.

20. Zhang Y, Zhang H, Ghosh D. The stabilizing excipients in dry state therapeutic phage formulations. AAPS PharmSciTech, 21:1-14, 2020.

19. Leal J, Peng X, Liu X, Arasappan D, Wylie D, Schwartz SH, Fullmer JJ, McWilliams BC, Smyth HDC, Ghosh D*. Peptides as Surface Coatings of Nanoparticles That Penetrate Human Cystic Fibrosis Sputum and Uniformly Distribute in Vivo Following Pulmonary Delivery. Journal of Controlled Release, 322:457-469, 2020. doi: 10.1016/j.jconrel.2020.03.032.

18. Mohanty RP, Liu X, Kim JY, Peng X, Bhandari S, Leal J, Arasappan D, Wylie D, Dong T, Ghosh D*. Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment.  Nanoscale, 11:17664-17681, 2019. doi: 10.1039/c9nr05783h.

17. Liu X, Ghosh D*. Intracellular nanoparticle delivery by oncogenic KRAS-mediated macropinocytosis. International Journal of Nanomedicine, 14: 6589-6600, 2019.

16. Peng X, Liu X, Liu YL, Kim JY, Chen YI, Ang P, Nguyen A, Leal J, Yeh HC, Ghosh D*. Brain-penetrating peptides across the blood-brain barrier and extracellular-like space. ChemRxiv, 2019. doi: https://doi.org/10.26434/chemrxiv.8242871.

15.  Leal J, Liu X, Peng X, Mohanty RP, Arasappan D, Wylie D, Schwartz SH, Fullmer JJ, McWilliams BC, Smyth HDC, Ghosh D*. A combinatorial biomolecular strategy to identify peptides for improved transport across the sputum of cystic fibrosis patients and the underlying epithelia. bioRxiv, 2019. doi: https://doi.org/10.1101/659540.

14. Leal J, Dong T, Gao F, Soto M, Smyth HDC, Ghosh D*. M13 phage display to identify a permeating peptide against hyperconcentrated mucin. bioRxiv, 2019. doi: https://doi.org/10.1101/659573.

13. Mohanty RP, Liu X, Kim JY, Peng X, Bhandari S, Leal J, Arasappan D, Wylie D, Dong T, Ghosh D*. Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment. bioRxiv, 2019. doi: https://doi.org/10.1101/659524.

12. Leal J, Dong T, Taylor A, Siegrist E, Gao F, Smyth HDC, Ghosh, D*. Mucus-penetrating phage-displayed peptides for improved transport across a mucus-like model. International Journal of Pharmaceutics, 553: 57-64, 2018.

11. Peng, X, Leal, J, Mohanty, R, Soto, M, Ghosh D* Quantitative qPCR of T7 bacteriophages from biopanning. Journal of Visualized Experiments, 139, 2018.

10. Ghosh D*, Peng, X, Leal, J, Mohanty, R. Peptides as drug delivery vehicles across biological barriers. Journal of Pharmaceutical Investigation, 48, 89-111, 2018.

9. Zhang, Y, Peng, X, Zhang, H, Watts, AB, Ghosh D*. Manufacturing and ambient stability of shelf freeze dried bacteriophage powder formulations. International Journal of Pharmaceutics, 542: 1-7, 2018.

8. Peng, X, Nguyen, A, Ghosh D*. Quantification of M13 and T7 bacteriophages by TaqMan and SYBR Green qPCR. Journal of Virological Methods, 252: 100-107, 2018.

7. Leal J, Smyth. HDC, Ghosh D*. Physicochemical properties of mucus and their impact on transmucosal drug delivery. International Journal of Pharmaceutics, 532: 555-572, 2017.

6. Ghosh D, Bagley AF, Na YJ, Birrer MS, Bhatia SN, Belcher AM*. Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes. Proceedings of the National Academy of Science, 111: 13948-13953, 2014.

5. Bardhan NM, Ghosh D, Belcher AM*. Carbon nanotubes as in vivo bacterial probes. Nature Communications, 5: 4918, 2014.

4. Bardhan NM, Ghosh D, Belcher AM*. M13 virus based detection of bacterial infections in living hosts. Journal of Photonics, 7: 617-623, 2014.

3. Ghosh D, Kohli AG, Moser F, Endy D, Belcher AM*. Refactored M13 bacteriophage as a platform for tumor cell imaging and drug delivery. ACS Synthetic Biology, 1: 576-582, 2012.

2. Ghosh D, Lee Y. Thomas S, Kohli AG, Yun DS, Belcher AM, Kelly KA*. M13-templated magnetic nanoparticles for targeted in vivo imaging of prostate cancer. Nature Nanotechnology, 7: 677-682, 2012.

1. Yi H, Ghosh D (joint first author), Ham MH, Qi J, Yun DS, Kim, WJ, Strano MS, Belcher AM*. M13 phage-functionalized single-walled carbon nanotubes as nanoprobes for second near-infrared window fluorescent imaging of targeted tumors. Nano Letters, 12: 1176-83, 2012.

 

Integrating pharmaceutical sciences with bio-materials for drug delivery across biological barriers

Social Widgets powered by AB-WebLog.com.