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Is eating raw eggs good for you, and can it help build muscle?

Recent social media trends have shown influencers consuming raw eggs, particularly after workouts. That has been popular at times over the years, and was featured in the original Rocky movie. It has returned and become a phenomenon to include raw eggs in protein shakes or smoothies. However, given the potential consequences of eating raw eggs, it is important to think twice about this issue. Is it good for you to eat raw eggs, and can it really help build muscle mass?

According to the Cleveland Clinic, it is not safe to consume raw eggs under any circumstance (1). Most eggs are pasteurized, meaning they are heated in a warm water bath to kill bacteria that could make you sick. However, even pasteurized eggs can still contain Salmonella, which can lead to diarrhea, cramps, or more serious illness. In a 2019 report by the European Food Safety Authority, eggs and egg products comprise 5.3% of all foodborne Salmonella outbreaks and are the foods most commonly associated with Salmonella (2). Therefore, physicians recommend eating eggs that are both pasteurized AND cooked.

Another reason physicians recommend not consuming raw eggs is that you can receive the same benefits from eating a cooked egg. One study compared muscle growth in 45 young men randomly assigned to consume 5 raw eggs or 5 hard boiled eggs after exercise (3). Between the two groups, researchers found no significant difference in muscle protein synthesis rates between young men who ate raw versus hard boiled eggs, suggesting that eating raw eggs did not offer an advantage for building muscle.

In this vein, another study showed that raw egg is more poorly absorbed during digestion than cooked egg, and cooking eggs can facilitate more complete digestion (4). However, this study investigated digestion of 5 participants, so more research is needed to conclude how raw versus cooked eggs are digested. Nevertheless, cooking is known to increase digestion of many foods.

Given this research, you don’t need to follow influencers by consuming raw eggs or put them in protein shakes to build muscle mass. A hard- boiled egg will do the trick! Remember to always Think Twice!

Sources

Cleveland Clinic. “Is Eating Raw Eggs Bad?” April 6, 2022. https://health.clevelandclinic.org/can-you-eat-raw-eggs

Oh, Hyemin et al. “Quantitative risk assessment of foodborne Salmonella illness by estimating cooking effect on eggs from retail markets.” Journal of animal science and technology vol. 65,5 (2023): 1024-1039. doi:10.5187/jast.2023.e18

Fuchs, Cas J et al. “Raw Eggs To Support Postexercise Recovery in Healthy Young Men: Did Rocky Get It Right or Wrong?.” The Journal of nutrition vol. 152,11 (2022): 2376-2386. doi:10.1093/jn/nxac174

Evenepoel P, Geypens B, Luypaerts A, Hiele M, Ghoos Y, Rutgeerts P. Digestibility of cooked and raw egg protein in humans as assessed by stable isotope techniques. J Nutr. 1998 Oct;128(10):1716-22. doi: 10.1093/jn/128.10.1716. PMID: 9772141.

Can cranberry juice treat urinary tract infections?

Over Thanksgiving, we might indulge in cranberry sauce or cranberry juice as part of our holiday traditions. While some love cranberry products and others do not, are there benefits to consuming cranberries? Specifically, can cranberry juice prevent urinary tract infections?

Urinary tract infections (UTIs) are bacterial infections that occur when bacteria enter the urethra (part of the urinary tract) from the skin or rectum (1). UTIs are often treated by a short course of antibiotics and will clear up within a few days of treatment (2). It is often stated that drinking cranberry juice can help prevent or clear up UTIs. Let’s think twice.

A 1998 systematic review found no randomized controlled trials of cranberry juice as treatment for UTIs (3), and we couldn’t find any done since. Cranberry juice is not a treatment for UTI.

In terms of prophylaxis, a meta-analysis of randomized controlled trials found a 54% lower rate of UTIs with cranberry juice consumption and a 49% lower rate with other liquids (4). Greater liquid intake is associated with fewer UTIs, but it’s not clear that cranberry juice is more effective than other liquids for prophylaxis.

One limitation of studies of the relationship between UTIs and cranberry is the use of a variety of cranberry products, for example, juice or capsules (5). Though you are likely not preventing a UTI, you can indulge in cranberry foods this season for the sake of holiday tradition.

1. Centers for Disease Control and Prevention. “Urinary Tract Infection Basics.” Jan. 2024. https://www.cdc.gov/uti/about/index.html

2. May Clinic. “Urinary Tract Infection (UTI).” Sep. 2022. https://www.mayoclinic.org/diseases-conditions/urinary-tract-infection/diagnosis-treatment/drc-20353453

3. Jepson, R G et al. “Cranberries for treating urinary tract infections.” The Cochrane database of systematic reviews vol. 1998,2 (2000): CD001322. doi:10.1002/14651858.CD001322

4. Moro, Christian et al. “Cranberry Juice, Cranberry Tablets, or Liquid Therapies for Urinary Tract Infection: A Systematic Review and Network Meta-analysis.” European Urology Focus, S2405-4569(24)00122-6. 18 Jul. 2024, doi:10.1016/j.euf.2024.07.002

5. R. Raz, B. Chazan, M. Dan, Cranberry Juice and Urinary Tract Infection, Clinical Infectious Diseases, Volume 38, Issue 10, 15 May 2004, Pages 1413–1419, https://doi.org/10.1086/386328?

Does emergency contraception affect fertility?

Emergency contraception, better known by its brand name, Plan B, can be taken after unprotected sex to prevent pregnancy. It can be purchased over the counter at your local pharmacy. However, on social media, there is some sense of worry that emergency contraception will affect future fertility, especially if taken repeatedly. Let’s think twice: does emergency contraception affect fertility?

Emergency contraception typically consists of the hormone levonorgestrel, which is a synthetic form of the hormone progesterone (1). Progesterone is a natural hormone in the body that helps regulate the menstrual cycle and increases during pregnancy (2). Levonorgestrel delays ovulation to prevent pregnancy (3).

A 2022 systematic review of levonorgestrel emergency contraception analyzed 33 studies and found that it did not affect fallopian tube mobility, ectopic pregnancy, miscarriage, stillbirth, or subsequent menstruations (3). Another systematic review of 47 studies found that adverse outcomes like ectopic pregnancy and miscarriage were not significantly associated with taking levonorgestrel emergency contraception (4). Researchers reported that “the most common adverse effects of levonorgestrel were not serious.” Temporary side effects reported after emergency contraception use include nausea and vomiting, vaginal bleeding, and fatigue (7). In one observational study of 232 participants reported transient changes in their menstruation (6).

A 2014 systematic review of 22 studies evaluated the repeated use of emergency contraception as the primary source of contraception and reported that the most common side effect was menstrual irregularities (5). The researchers concluded that more investigation is required since the existing studies on repeated usage were not methodologically sound. Also, many menstrual cycles are irregular and pregnancy alone might alter them, making objective measurement of the cycle for several months before and after important, which is difficult and perhaps impossible.

Emergency contraception can reduce the probability of conception after unprotected sex (8) and is a safe and effective medication that does not impact future fertility.

Sources

Gillson, George. “Clarifying hormone terminology.” Canadian family physician Medecin de famille canadien vol. 53,1 (2007): 29-30.

Cable JK, Grider MH. Physiology, Progesterone. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558960/

Endler, M et al. “Effect of levonorgestrel emergency contraception on implantation and fertility: A review.” Contraception vol. 109 (2022): 8-18. doi:10.1016/j.contraception.2022.01.006

Leelakanok, Nattawut, and Janthima Methaneethorn. “A Systematic Review and Meta-analysis of the Adverse Effects of Levonorgestrel Emergency Oral Contraceptive.” Clinical drug investigation vol. 40,5 (2020): 395-420. doi:10.1007/s40261-020-00901-x

Halpern, Vera et al. “Repeated use of pre- and postcoital hormonal contraception for prevention of pregnancy.” The Cochrane database of systematic reviews vol. 2014,9 CD007595. 26 Sep. 2014, doi:10.1002/14651858.CD007595.pub3

Gainer, Erin et al. “Menstrual bleeding patterns following levonorgestrel emergency contraception.” Contraception vol. 74,2 (2006): 118-24. doi:10.1016/j.contraception.2006.02.009

World Health Organization. “Emergency Contraception.” (2021). https://www.who.int/news-room/fact-sheets/detail/emergency-contraception#:~:text=Emergency%20contraception%20(EC)%20can%20prevent,assault%20if%20without%20contraception%20coverage.