2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008 | 2007 | 2005 | 2004 | Review Articles | Book Chapters
Peer-reviewed Manuscripts
2024
2023
A global sensitivity analysis of a mechanistic model of neoadjuvant chemotherapy for triple-negative breast cancer constrained by in vitro and in vivo imaging data
Lorenzo G, Jarrett AM, Meyer CT, DiCarlo JC, Virostko J, Quaranta V, Tyson DR, Yankeelov TE
Engineering with Computers. 2023
Comparing mechanism-based and machine learning models for predicting the effects of glucose accessibility on tumor cell proliferation
Yang J, Virostko J, Liu J, Jarrett AM, Hormuth DA 2nd, Yankeelov TE
Sci Rep. 2023 Jun 27;13(1):10387
Toward Practical Integration of Omic and Imaging Data in Co-Clinical Trials
Alkim E, Dowst H, DiCarlo J, Dobrolecki LE, Hernández-Herrera A, Hormuth DA 2nd, Liao Y, McOwiti A, Pautler R, Rimawi M, Roark A, Srinivasan RR, Virostko J, Zhang B, Zheng F, Rubin DL, Yankeelov TE, Lewis MT
Tomography. 2023 Apr 10;9(2):810-828
Longitudinal MRI Shows Progressive Decline in Pancreas Size and Altered Pancreas Shape in Type 1 Diabetes
Wright JJ, Dulaney A, Williams JM, Hilmes MA, Du L, Kang H, Powers AC, Moore DJ, Virostko J
J Clin Endocrinol Metab. 2023 Sep 18;108(10):2699-2707
Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas. Diabetes Care
Wright JJ, Williams JM, Letourneau-Freiberg LR, Kandasamy B, Reyes D, Kanegusuku AG, Philipson L, Greeley SAW, Hilmes MA, Powers AC, Virostko J, Moore DJ
Diabetes Care. 2023 Apr 1;46(4):773-776
An untrained deep learning model for reconstructing dynamic MR images from accelerated model-based data
Slavkova KP, DiCarlo JC, Wadwa V, Kumar S, Wu C, Virostko J, Yankeelov TE, Tamir JI
Magn Reson Med. 2023 Apr;89(4):1617-1633
Analysis of simplicial complexes to determine when to sample for quantitative DCE MRI of the breast
DiCarlo JC, Jarrett AM, Kazerouni AS, Virostko J, Sorace A, Slavkova KP, Woodard S, Avery S, Patt D, Goodgame B, Yankeelov TE
Magn Reson Med. 2023 Mar;89(3):1134-1150
2022
Quantifying the Effects of Combination Trastuzumab and Radiation Therapy in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer
Bloom MJ, Song PN, Virostko J, Yankeelov TE, Sorace AG
Cancers. 2022 Aug 31;14(17):4234
Integrating mechanism-based modeling with biomedical imaging to build practical digital twins for clinical oncology
Wu C, Lorenzo G, Hormuth DA, Lima EABF, Slavkova KP, DiCarlo JC, Virostko J, Phillips CM, Patt D, Chung D, Yankeelov TE
Biophysics Rev. 2022 Jun;3(2):021304
Quantifying Tumor Heterogeneity via MRI Habitats to Characterize Microenvironmental Alterations in HER2+ Breast Cancer
Kazerouni AS, Hormuth DA, Davis T, Bloom MJ, Mounho S, Rahman G, Virostko J, Yankeelov TE, Sorace AG
Cancers. 2022 Apr 6;14(7):1837
Longitudinal FRET Imaging of Glucose and Lactate Dynamics and Response to Therapy in Breast Cancer Cells
Yang J, Davis T, Kazerouni AS, Chen YI, Bloom MJ, Yeh HC, Yankeelov TE, Virostko J
Mol Imaging Biol. 2022 Feb;24(1):144-155
Deep learning-based pancreas volume assessment in individuals with type 1 diabetes
Roger R, Hilmes MA, Williams JM, Moore DJ, Powers AC, Craddock RC, Virostko J
BMC Medical Imaging. 2022 Jan 5;22(1):5
2021
Bayesian calibration of a stochastic, multiscale agent-based model for predicting in vitro tumor growth
Lima EABF, Faghihi D, Philley R, Yang J, Virostko J, Phillips CM, Yankeelov TE
PLoS Comput Biol. 2021 Nov 29;17(11):e1008845
Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting
Virostko J, Sorace AG, Slavkova KP, Kazerouni AS, Jarrett AM, DiCarlo JC, Woodard S, Avery S, Goodgame B, Patt D, Yankeelov TE
Breast Cancer Res. 2021 Nov 27;23(1):110
Quantitative magnetic resonance imaging and tumor forecasting of breast cancer patients in the community setting
Jarrett AM, Kazerouni AS, Wu C, Virostko J, Sorace AG, DiCarlo JC, Hormuth DA 2nd, Ekrut DA, Patt D, Goodgame B, Avery S, Yankeelov TE
Nat Protoc. 2021 Nov;16(11):5309-5338
Development of a standardized MRI protocol for pancreas assessment in humans
Virostko J, Craddock RC, Williams JM, Triolo TM, Hilmes MA, Kang H, Du L, Wright JJ, Kinney M, Maki JH, Medved M, Waibel M, Kay TWH, Thomas HE, Greeley SAW, Steck AK, Moore DJ, Powers AC
PLoS One. 2021 Aug 24;16(8)
An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines
Yang J, Virostko J, Hormuth DA 2nd, Liu J, Brock A, Kowalski J, Yankeelov TE
PLoS One. 2021 Jul 13;16(7)
Characterizing Errors in Pharmacokinetic Parameters from Analyzing Quantitative Abbreviated DCE-MRI Data in Breast Cancer
Slavkova KP, DiCarlo JC, Kazerouni AS, Virostko J, Sorace AG, Patt D, Goodgame B, Yankeelov TE
Tomography. 2021 Jun 23;7(3):253-267
The rate of breast fibroglandular enhancement during dynamic contrast-enhanced MRI reflects response to neoadjuvant therapy
Virostko J, Kuketz G, Higgins E, Wu C, Sorace AG, DiCarlo JC, Avery S, Patt D, Goodgame B, Yankeelov TE
Eur J Radiol. 2021 Jan 9;136:109534
2020
Evaluating patient-specific neoadjuvant regimens for breast cancer via a mathematical model constrained by quantitative magnetic resonance imaging data
Jarrett AM, Hormuth DA 2nd, Wu C, Kazerouni AS, Ekrut DA, Virostko J, Sorace AG, DiCarlo JC, Kowalski J, Patt D, Goodgame B, Avery S, Yankeelov TE
Neoplasia. 2020 Nov 13;22(12):820-830
Repeatability and Reproducibility of Pancreas Volume Measurements Using MRI
Williams JM, Hilmes MA, Archer B, Dulaney A, Du L, Kang H, Russell WE, Powers AC, Moore DJ, Virostko J
Sci Rep. 2020 Mar 16;10(1):4767
Reply to Appropriate considerations of “rural” in National Cancer Data Base analyses
Virostko J, Capasso A, Yankeelov TE, Goodgame B
Cancer. 2020 Apr 1;126(7):1586-1587
2019
Recent trends in the age at diagnosis of colorectal cancer in the US National Cancer Data Base, 2004-2015
Virostko J, Capasso A, Yankeelov TE, Goodgame B
Cancer. 2019 Nov 1;125(21):3828-3835
Magnetization Transfer MRI of Breast Cancer in the Community Setting: Reproducibility and Preliminary Results in Neoadjuvant Therapy
Virostko J, Sorace AG, Wu C, Ekrut D, Jarrett AM, Upadhyaya RM, Avery S, Patt D, Goodgame B, Yankeelov TE
Tomography. 2019 Mar;5(1):44-52
Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis
Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, Sévigny J, Powers AC
Cell Metab. 2019 Mar 5;29(3):745-754
Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset
Virostko J, Williams J, Hilmes M, Bowman C, Wright JJ, Du L, Kang H, Russell WE, Powers AC, Moore DJ
Diabetes Care. 2019 Feb;42(2):248-257
2018
Fully Convolutional Neural Networks Improve Abdominal Organ Segmentation
Bobo MF, Bao S, Huo Y, Yao Y, Virostko J, Plassard AJ, Lyu I, Assad A, Abramson RG, Hilmes MA, Landman BA
Proc SPIE Int Soc Opt Eng. 2018 Mar;10574
Repeatability, reproducibility, and accuracy of quantitative MRI of the breast in the community radiology setting
Sorace AG, Wu C, Barnes SL, Jarrett AM, Avery S, Patt D, Goodgame B, Luci JJ, Kang H, Abramson RG, Yankeelov TE, Virostko J
J Magn Reson Imaging. 2018 Mar 23
Integrated molecular imaging reveals tissue heterogeneity driving host-pathogen interactions
Cassat JE, Moore JL, Wilson KJ, Stark Z, Prentice BM, Van de Plas R, Perry WJ, Zhang Y, Virostko J, Colvin DC, Rose KL, Judd AM, Reyzer ML, Spraggins JM, Grunenwald CM, Gore JC, Caprioli RM, Skaar EP
Sci Transl Med. 2018 Mar 14;10(432)
Distinguishing benign and malignant breast tumors: preliminary comparison of kinetic modeling approaches using multi-institutional dynamic contrast-enhanced MRI data from the International Breast MR Consortium 6883 trial
Sorace AG, Partridge SC, Li X, Virostko J, Barnes SL, Hippe DS, Huang W, Yankeelov TE
J. Med. Imag. 2018 Jan. 5(1), 011019
Dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted magnetic resonance imaging for predicting the response of locally advanced breast cancer to neoadjuvant therapy: a meta-analysis
Virostko J, Hainline A, Kang H, Arlinghaus LR, Abramson RG, Barnes SL, Blume JD, Sarah Avery, Patt D, Goodgame B., Yankeelov TE, Sorace AG
J. Med. Imag. 2018 Jan; 5(1), 011011
2016
Use of the Electronic Medical Record to Assess Pancreas Size in Type 1 Diabetes
Virostko J, Hilmes M, Eitel K, Moore DJ, Powers AC
PLoS One. 2016 Jul 8;11(7)
2015
Quantitative Correlation of in Vivo Properties with in Vitro Assay Results: The in Vitro Binding of a Biotin-DNA Analogue Modifier with Streptavidin Predicts the in Vivo Avidin-Induced Clearability of the Analogue-Modified Antibody
Dou S, Virostko J, Greiner DL, Powers AC, Liu G
Mol Pharm. 2015 Aug 3;12(8):3097-10
A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity
Dou S, Virostko J, Greiner DL, Powers AC, Liu G
Nucleosides Nucleotides Nucleic Acids. 2015 Feb;34(2):69-78
Detection of breast cancer microcalcification using 99mTc-MDP SPECT or Osteosense 750EX FMT imaging
Felix DD, Gore JC, Yankeelov TE, Peterson TE, Barnes S, Whisenant J, Weis J, Shoukouhi S, Virostko J, Nickels M, McIntyre JO, Sanders M, Abramson V, Tantawy MN
Nucl Med Biol. 2015 Mar;42(3):269-73
2014
Reply to ‘Assessment of MRI issues at 7 T’
Dula AN, Virostko J, Shellock FG
AJR Am J Roentgenol. 2014 Nov;203(5):W561
Non-Invasive Bioluminescence Imaging of β-Cell Function in Obese-Hyperglycemic [ob/ob] Mice
Patel M, Gleason A, O’Malley S, Connolly B, Suresch D, Virostko J, Phillips N, Lin SA, Chen TB, Klimas M, Hargreaves RJ, Sur C, Williams DL Jr, Powers AC, Bednar B
PLoS One. 2014 Sep 8;9(9):e106693
Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice
Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC and Liu G
Front. Pharmacol. 2014 July;5:172
Assessment of MRI issues at 7 T for 28 implants and other objects
Dula AN, Virostko J, Shellock FG
AJR Am J Roentgenol. 2014 Feb;202(2):401-5
2013
SPARCL1 suppresses metastasis in prostate cancer
Xiang Y, Qiu Q, Jiang M, Jin R, Lehmann BD, Strand DW, Jovanovic B, DeGraff DJ, Zheng Y, Yousif DA, Simmons CQ, Case TC, Yi J, Cates JM, Virostko J, He X, Jin X, Hayward SW, Matusik RJ, George AL Jr, Yi Y
Mol Oncol. 2013 Dec;7(6):1019-30
A Novel Reporter System for Molecular Imaging and High-Throughput Screening of Anticancer Drugs
Xie J, Wang C, Virostko J, Manning HC, Pham W, Bauer J, Gore JC
Chembiochem. 2013 Aug 19;14(12):1494-503
Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse model
Virostko J, Radhika A, Poffenberger G, Dula AN, Moore DJ, Powers AC
PLoS One. 2013;8(3):e57784
2011
Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands
Virostko J, Henske J, Vinet L, Lamprianou S, Dai C, Radhika A, Baldwin RM, Ansari MS, Hefti F, Skovronsky D, Kung HF, Herrera PL, Peterson TE, Meda P, Powers AC
Proc Natl Acad Sci USA. 2011 Dec 20;108(51):20719-24
2010
Magnetic nanoparticles for imaging dendritic cells
Kobukai S, Baheza R, Cobb JG, Virostko J, Xie J, Gillman A, Koktysh D, Kerns D, Does M, Gore JC, Pham W
Magn Reson Med. 2010 May;63(5):1383-90
Bioluminescence Imaging in Mouse Models Quantifies beta Cell Mass in the Pancreas and After Islet Transplantation
Virostko J, Radhika A, Poffenberger G, Chen Z, Brissova M, Gilchrist J, Coleman B, Gannon M, Jansen ED, Powers AC
Mol Imaging Biol. 2010 Jan-Feb;12(1):42-53
2009
A Molecular Imaging Paradigm to Rapidly Profile Response to Angiogenesis-directed Therapy in Small Animals
Virostko J, Xie J, Hallahan DE, Arteaga CL, Gore JC, Manning HC
Mol Imaging Biol. 2009 May-Jun;11(3):204-12
2008
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer
Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, McKinley ET, Xie J, Mutic NJ, Washington MK, LaFleur B, Tantawy MN, Peterson TE, Ansari MS, Baldwin RM, Rothenberg ML, Bornhop DJ, Gore JC, Coffey RJ
Clin Cancer Res. 2008 Nov 15;14(22):7413-22
2007
Validation of Luminescent Course Reconstruction Using Single-view Spectrally Resolved Bioluminescence Images
Virostko J, Powers AC, Jansen ED
Applied Optics. 2007 May 1; 46(13): 2540-7
2005
Effect of optical tissue clearing on spatial resolution and sensitivity of bioluminescence imaging
Jansen ED, Pickett PM, Mackanos MA, Virostko J
Journal of Biomedical Optics. 2005 Aug 25; 11(4)
Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging
Fowler M, Virostko J, Chen Z, Poffenberger G, Radhika A, Brissova M, Shiota M, Nicholson WE, Shi Y, Hirshberg B, Harlan DM, Jansen ED, Powers AC
Transplantation. 2005 Apr 15; 79(7): 768-76
2004
Factors influencing quantification of in vivo bioluminescence imaging: application to assessment of pancreatic islet transplants
Virostko J, Chen Z, Fowler M, Poffenberger G, Powers AC, Jansen ED
Molecular Imaging. 2004 Oct; 3(4): 333-42
Review Articles
Cross-sectional imaging of the pancreas in diabetes. Virostko J. Abdom Radiol (NY). 2024 Apr 1.
Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes
Virostko J
Frontiers in Endocrinology. 2020 Dec 4;11:592349.
Optimal Control Theory for Personalized Therapeutic Regimens in Oncology: Background, History, Challenges, and Opportunities
Jarrett AM, Faghihi D, Ii DAH, Lima EABF, Virostko J, Biros G, Patt D, Yankeelov TE
J Clin Med. 2020 May 2;9(5)
Translating preclinical MRI methods to clinical oncology
Hormuth DA 2nd, Sorace AG, Virostko J, Abramson RG, Bhujwalla ZM, Enriquez-Navas P, Gillies R, Hazle JD, Mason RP, Quarles CC, Weis JA, Whisenant JG, Xu J, Yankeelov TE
J Magn Reson Imaging. 2019 Nov;50(5):1377-1392
Recent Efforts to Develop Imaging Methods and Beta-Cell-Specific Contrast Agents for Non-Invasive in vivo Assessment of Beta-Cell Mass
Schneider S, Virostko J, Reimann A, Powers AC
Recent Patents on Endocrine Metabolic & Immune Drug Discovery. 2009 Nov;3(3):157-161
Molecular Imaging of the Pancreas in Small Animal Models
Virostko J, Powers AC
Gastroenterology. 2009 Feb;136(2):407-9
Current status of imaging pancreatic islets
Virostko J, Jansen ED, Powers AC
Current Diabetes Reports. 2006 Aug; 6(4): 328-32
Book Chapters
“Quantitative Imaging Using MRI.” In: Radiomics and Radiogenomics Technical Basis and Clinical Applications
Hormuth DA, Virostko J, Stokes A, Dula A, Sorace AG, Whisenant JG, Weis JA, Quarles CC, Miga MI, Yankeelov TE
“Quantitative Imaging Using MRI.” In: Radiomics and Radiogenomics Technical Basis and Clinical Applications. Ruijiang Li, Lei Xing, Sandy Napel, Daniel L. Rubin, eds. New York, New York: Chapman and Hall; 2019: 73-98
“Validation of bioluminescent imaging techniques.” In: Bioluminescence Methods and Protocols 2nd ed
Virostko J, Jansen ED
“Validation of bioluminescent imaging techniques.” In: Bioluminescence Methods and Protocols 2nd ed. Preston B. Rich and Christelle Douillet, eds. New York, New York: Humana Press; 2009: 15-23.