The MAMA Study consists of 4 study visits, 3 of which will take place during pregnancy and one that will take place approximately one year postpartum. Study visits will take place at the University of Texas at Austin Health Discovery Building and each visit will take up to 3 hours. Participants will be compensated up to $500 total for completing all study visits.

During study visits, participants will have anthropometric and blood pressure measurements taken, complete a Magnetic Resonance Imaging (MRI) scan, have their blood drawn, complete a Hemoglobin A1C (HbA1c) test, complete Oral Glucose Tolerance Testing (OGTT), and have a Continuous Glucose Monitor (CGM) inserted. When available, standard of care laboratory results relevant to the study may be requested.

Location of Study Visits:

Dell Medical School – Health Discovery Building

1601 Trinity St Building B

Austin, TX 78701

Pregnancy Visit 1 (15-18 weeks gestation)

• Location: Health Discovery Building
• At the study visit, you will:

1. Review and sign paperwork, including study screening and consent forms
2. Complete an MRI scan, which will last approximately 40 minutes
3. Have your blood drawn, complete an HbA1c test, and complete OGTT, which will take approximately 2 hours
4. Have blood pressure and anthropometric measurements taken: you will self-report height and weight at this visit
5. Have a CGM sensor inserted just under your skin: you will wear this sensor for a week and will be given disposal instructions
6. When available, standard of care laboratory results relevant to the study may be requested

Pregnancy Visit 2 (24-28 weeks gestation)

• Location: Health Discovery Building
• At the study visit, you will:

1. Complete an MRI scan, which will last approximately 40 minutes
2. Have your blood drawn, complete an HbA1c test, and complete OGTT, which will take approximately 2 hours
3. Have blood pressure and anthropometric measurements taken: you will self-report height and weight at this visit
4. Have a CGM sensor inserted just under your skin: you will wear this sensor for a week and will be given disposal instructions

Pregnancy Visit 3 (34-38 weeks gestation)

• Location: Health Discovery Building
• At the study visit, you will:

1. Complete an MRI scan, which will last approximately 40 minutes
2. Have your blood drawn, complete an HbA1c test, and complete OGTT, which will take approximately 2 hours
3. Have blood pressure and anthropometric measurements taken: you will self-report height and weight at this visit
4. Have a CGM sensor inserted just under your skin: you will wear this sensor for a week and will be given disposal instructions

Postpartum Visit 4 (1 year-1 year and 2 months postpartum)

• Location: Health Discovery Building
• At the study visit, you will:

1. Complete an MRI scan, which will last approximately 40 minutes
2. Have your blood drawn, complete an HbA1c test, and complete OGTT, which will take approximately 2 hours
3. Have blood pressure and anthropometric measurements taken: you will self-report height and weight at this visit
4. Have a CGM sensor inserted just under your skin: you will wear this sensor for a week and will be given disposal instructions
5. Be given a framed set of your baby’s MRI images, taken at each study visit as they grow (see example image below).

We are currently enrolling participants in the MAMA study. If you are interested in participating in the MAMA study, please complete this screening form and we will reach out to you about your eligibility.

For more information about study visits, please reference our FAQ page or contact a study team member here.