Sex Differences in COVID-19
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How Does Gender Impact Long COVID?
Written by: Akshara Ramasamy Edited by: Esther Melamed Among the several health impacts of the COVID-19 pandemic, a few medical challenges remain, including understanding the etiology of long COVID. Long COVID, also known as Post-acute sequelae of COVID-19 (PASC), refers to a wide range of new or worsening health problems that patients may encounter after being…
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Neutralizing Autoantibodies Predict COVID-19 Disease Course and Severity
OCTOBER 8, 2020 BY PARKER DAVIS Though the disease course of COVID-19 follows a relatively predetermined and predictable progression, any number of comorbidities that a patient possesses may serve to derail or modify the patient’s clinical trajectory. From hypertension, to diabetes, to various cardiac and cerebrovascular diseases, these underlying pathologies are some of the prime factors that…
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What role does estrogen play in the COVID-19 sex difference?
Previous entries in this blog have shown that men who contract the SARS-CoV-2 virus are more likely to develop severe disease symptoms than women. The closely related coronavirus SARS-CoV-1, which also targets the ACE2 protein for cell adhesion and infiltration, showed a similar sexual disparity during the 2002-2004 SARS epidemic. Research into the mechanisms of…
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What is driving the sex difference in COVID-19?
The current evidence for a male predisposition toward increased risk of severe disease from SARS-CoV-2 infection is consistent across age groups and cultural demographics. Smoking was examined as a possible risk factor based on early studies on COVID-19 epidemiology out of China, where the noticable sex difference in disease severity was paired with a national…
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Are there sex differences in COVID-19 epidemiology?
As the novel coronavirus continues to spread across the world, global health organizations have begun to identify patterns of uniquely susceptible populations. When discussing the epidemiology of this virus, it is important to distinguish between SARS-CoV-2 infection and the development of the COVID-19 disease. Approximately 50% of people who become infected with the virus do…