Junling Bu (卜俊玲)

Degrees: 

B.S., Traditional Chinese Medicine Resources, 2013-2017, Nanjing University of Chinese Medicine

Ph.D., Traditional Chinese Medicine (Molecular Pharmacognosy), 2017-2022, China Academy of Chinese Medical Sciences (CACMS) (Advisor Dr. Lu-Qi Huang)

Entered Group: Spring, 2023

Research Projects: Natural product biosynthesis, mechanistic study of biosynthetic enzymes

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Group Publications:

Zheng, Z.; Xiong, J.; Bu, J.; Ren, D.; Lee, Y.-H.; Yeh, Y.-C.; Lin, C.-I.; Parry, R.; Guo, Y.; Liu, H.-w. “Reconstitution of the Final Steps in the Biosynthesis of Valanimycin Reveals the Origin of its Characteristic Azoxy Moiety.” Angew. Chem. Int. Ed. 2024, 63, e202315844. [PMC10843709]

Zhao, H.; Bu, J.; Liu, H.-w. “Radical S-Adenosylmethionine Sulfurtransferase MybB Catalyzed Formation of the 4-Thiazolidinone Core in Mycobacidin Represents an Intersection between Primary and Secondary Metabolism.” J. Am. Chem. Soc. 2025, 147, 4180-4187. [PMC11826332]

Kim, W.; Fan, P.-h.; Bu, J.; Liu, H.-w.; Zhang, Y. J. “Structural-guided Mechanistic Investigation of Stereochemical Inversion During the Octose Formation Catalyzed by an Atypical Transaldolase AprG in the Biosynthesis of Apramycin.” ACS Catal. 2025, 15, 13778-13786. [PMC12377196]