Anthony Romo

Anthony RomoDegree: Pharm.D., University of Texas at Austin

Entered Group: Fall, 2007 (as an Undergrad Research Assistant)

Pharm.D/Ph.D program, Fall, 2009

Research Projects: Studies of the Biosynthesis of Unusual Sugars and Secondary Metabolites

Group Publications:

Romo, A. J.; Liu, H.-w. “Coenzyme B6-Dependent Enzymes Involved in the Biosynthesis of Deoxy Sugars and Amino Sugars.” Biochem. Biophys. Acta Proteins & Proteomics 2011, 1814, 1534-1547.

Huang, H.; Chang, W.-C.; Pai, P.-J.; Romo, A.; Mansoorabadi, S. O.; Russell, D. H.; Liu, H.-w. “Evidence of a Radical-Mediated Mechanism in HppE-catalyzed Oxidation Reaction – A Study of Cyclopropyl and Methylenecyclopropyl Substrate Analogues. ” J. Am. Chem. Soc. 2012, 134, 16171-16174.

Al-Mestarihi, A.; Romo, A. R.; Liu, H.-w.; Bachmann, B. O. “Nitrososynthase Triggered Oxidative Carbon-Carbon Bond Cleavage in Baumycin Biosynthesis. ” J. Am. Chem. Soc. 2013, 135, 11457-11460.

Huang, H.; Chang, W.-C.; Lin, G.-M.; Romo, A.; Pai, P.-J.; Russell, D. H.; Liu, H.-w. “Mechanistic Consequences of Chiral Radical Clock Probes: Analysis of the Mononuclear Non-Heme Iron Enzyme HppE with 2-Hydroxy-3-methylenecyclopropyl Radical Clock Substrates. ” J. Am. Chem. Soc. 2014, 136, 2944-2947.

Lin, G.-M.; Romo, A. J.; Liem, P. H.; Chen, Z.; Liu, H.-w. “Identification and Interrogation of the Herbicidin Biosynthetic Gene Cluster: First Insight into the Biosynthesis of a Rare Undecose Nucleoside Antibiotic.” J. Am. Chem. Soc. 2017, 139, 16450-16453.

Romo, A.; Ikeuchi, H.; Shiraishi, T.; Lin, G.-M.; Geng, Y.; Lee, Y.-H.; Liem, P. H.; Ma, T.; Ogasawara, Y.; Shin-Ya, K.; Nishiyama, M.; Kuzuyama, T.; Liu, H.-w. “Miharamycins and Amipurimycin Biosynthetic Gene Clusters: Unravelling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics.” J. Am. Chem. Soc. 2019, 141, 14152-14159. [PMC6774755].