Degree: B.S., National Taiwan University
M.S., National Taiwan University
Entered Group: Fall, 2008
Research Projects: Studies of the Biosynthesis of Natural Products
Group Publications:
Sasaki, E.; Lin, C.-I.; Lin, K.-Y.; Liu, H.-w. “In vitro Characterization of LmbR and LmbN: Construction of the Octose 8-Phosphate Intermediate in Lincomycin A Biosynthesis.” J. Am. Chem. Soc. 2012, 134, 17432-17435.
Lin, C.-I.; McCarty, R. M.; Liu, H.-w. “The Biosynthesis of Nitrogen- Sulfur-, and Higher-carbon Chain Containing Sugars..” Chem. Soc. Rev. 2013, 42, 4377-4407.
Lin, C.-I.; Sasaki, E.; Zhong, A.; Liu, H.-w. “In Vitro Characterization of LmbK and LmbO: Identification of GDP-D-erythro-α-D-gluco-octose as a Key Intermediate in Lincomycin A Biosynthesis.” J. Am. Chem. Soc. 2014, 136, 906-909.
Shen, L.; Wang, Y.; Lin, C.-I.; Liu, Y.-n.; Liu, H.-w.; Guo, A.; Zhu, X.-Y. “Membrane Environment Can Enhance the Binding of Influenza A Virus Hemagglutinin to Cell Surface Glycan Receptors.” ACS Chem. Biol. 2014, 9, 1877-1884.
Ushimaru, R.; Lin, C.-I.; Sasaki, E.; Liu, H.-w. “Characterization of Enzymes Catalyzing Transformations of Cysteine S-Conjugated Intermediates in the Lincosamide Biosynthesis Pathway.” ChemBioChem 2016, 17, 1606-1611.
Lin, C.-I.; McCarty, R. M.; Liu, H.-w. “Enzymology of Organic Transformations: A Survey of Name Reactions in Biological Systems.” Angew Chem. Int. Ed. 2017, 56, 3446-3489.
Wang, S.-A.; Lin, C.-I.; Zhang, J.; Ushimaru, R.; Sasaki, E.; Liu, H.-w. “Studies of Lincosamide Formation Complete the Biosynthetic Pathway for Lincomycin A.” Proc. Natl. Acad. Sci. USA 2020, 117, 24794-24801.