Degree: B.S., Wuhan University, China
M.S., Wuhan University, China
Ph.D, Wuhan University, China
Entered Group: Spring, 2017
Research Projects: Mechanistic Studies of the Biosynthesis of Secondary Metabolites
Group Publications:
Pan, H.-X.; Chen, Z.; Zeng, T.; Jin, W.-B.; Geng, Y.; Lin, G.-M.; Zhao, J.; Li, W.-T.; Xiong, Z.; Huang, S.-X.; Zhai, X.; Liu, H.-w.; Tang, G.-L. “Elucidation of the Herbicidin Tailoring Pathway Offers New Insights into Its Structural Diversity.” Org. Lett. 2019, 21, 1374-1378.
Wang, S.-A.; Ko, Y.; Zheng, J.; Geng, Y.; Ren, D.; Ogasawara, Y.; Irani, S.; Zhang, Y.; Liu, H.-w. “Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay Between Biological Pyrazolopyrimidine Formation and de novo Purine Biosynthesis.” J. Am. Chem. Soc. 2019, 141, 6127-6131. [NIHMSID 1021733]
Romo, A.; Ikeuchi, H.; Shiraishi, T.; Lin, G.-M.; Geng, Y.; Lee, Y.-H.; Liem, P. H.; Ma, T.; Ogasawara, Y.; Shin-Ya, K.; Nishiyama, M.; Kuzuyama, T.; Liu, H.-w. “Miharamycins and Amipurimycin Biosynthetic Gene Clusters: Unravelling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics.” J. Am. Chem. Soc. 2019, 141, 14152-14159. [PMC6774755]
Ren, D.; Wang, S.-A.; Ko, Y.; Geng, Y.; Ogasawara, Y.; Liu, H.-w. “Identification of the C-Glycoside Synthases during Biosynthesis of the Pyrazole-C-Nucleosides Formycin and Pyrazofurin.” Angew. Chem. Int. Ed. 2019, 58, 16512-16516. [PMC6911263]
Chen, Z.; Sato. S.; Geng. Y., Zhang, J.; Liu, H.-w. “Identification of the Early Steps in Herbicidin Biosynthesis Reveals an Atypical C-Glycosylation.” J. Am. Chem. Soc. 2022, 144, in press.